Uneven Distribution of Ventilation and Diffusing Capacity in Patients with Chronic Pulmonary Emphysema

2015 ◽  
pp. 67-70
Author(s):  
Takeo Kawashiro ◽  
Yuichi Ichinose ◽  
Tetsuro Yokoyama
Keyword(s):  
Pulmonary Emphysema ◽  
Uneven Distribution ◽  
Diffusing Capacity ◽  
Chronic Pulmonary Emphysema

Lung volume, alveolar ventilation and perfusion interrelationships in chronic pulmonary emphysema

1960 ◽  
Vol 15 (5) ◽  
pp. 785-795 ◽  
Author(s):  
W. A. Briscoe ◽  
E. M. Cree ◽  
J. Filler ◽  
H. E. J. Houssay ◽  
A. Cournand
Keyword(s):  
Lung Volume ◽  
Pulmonary Emphysema ◽  
Blood Perfusion ◽  
Mean Value ◽  
Alveolar Ventilation ◽  
Diffusing Capacity ◽  
Nitrogen Washout ◽  
Arterial Blood ◽  
Chronic Pulmonary Emphysema ◽  
Ventilation And Perfusion

In 10 patients with chronic pulmonary emphysema the distribution of ventilation within the lungs was assessed by a nitrogen washout and washin technique. Alveolar ventilation per minute per unit lung volume had a mean value of 5.0 in well ventilated alveoli and 0.19, or 1/26 as much, in poorly ventilated alveoli. Distribution of blood perfusion was estimated by a new method from these data and from O2 consumption and arterial O2 saturation. On the average, poorly ventilated alveoli which constituted 66% of lung volume were perfused by not more than 52% of the cardiac output. Thus poorly ventilated alveoli were underperfused by blood. Ventilation/perfusion ratios averaged 2.24 in well ventilated alveoli and 0.23 in poorly ventilated alveoli. Oxygen saturation averaged 85% in arterial blood and 97frac12% and 76%, respectively, in end-capillary blood leaving well and poorly ventilated alveoli. Inhomogeneity of this degree within the lung invalidates calculations of diffusing capacity based on any single mean PaOO2 and of alveolar ventilation based on identification of mean alveolar Pco2 with arterial blood Pco2. Submitted on March 25, 1960

Cerebral circulation and metabolism in chronic pulmonary emphysema

1952 ◽  
Vol 12 (4) ◽  
pp. 382-387 ◽  
Author(s):  
John L. Patterson ◽  
Albert Heyman ◽  
T.Whatley Duke
Keyword(s):  
Cerebral Circulation ◽  
Pulmonary Emphysema ◽  
Chronic Pulmonary Emphysema

PULMONARY EMPHYSEMA AND OTHER CARDIORESPIRATORY LESIONS AS PART OF THE MARFAN ABIOTROPHY

PEDIATRICS ◽  
1964 ◽  
Vol 33 (3) ◽  
pp. 356-366
Author(s):  
Robert P. Bolande ◽  
Arthur S. Tucker
Keyword(s):  
Connective Tissue ◽  
Left Atrium ◽  
Pulmonary Emphysema ◽  
Left Lung ◽  
Left Main ◽  
Main Stem Bronchus ◽  
Giant Left Atrium ◽  
Left Main Stem Bronchus ◽  
The Right ◽  
Chronic Pulmonary Emphysema

Seven cases of Marfan's syndrome are reviewed clinically, radiologically, and pathologically. Six of the seven cases showed evidence of pulmonary dysaeration: (a) Two of the cases showed compression of the left main-stem bronchus by a giant left atrium with atelectasis of the left lung and compensatory emphysema of the right lung. (b) Two of the cases showed evidence of diffuse chronic pulmonary emphysema. Three cases had bilateral apical bullae. (c) One of the cases developed pneumothorax. The lungs of the children with the Marfan syndrome show precocious maturation of the elastic stroma of the alveolar septae. The pathogenesis of emphysema is discussed in relationship to the Marfan abiotrophy of connective tissue.

Morphologic and Histochemical Evaluation of Muscle in Patients with Chronic Pulmonary Emphysema Manifesting Generalized Emaciation

1997 ◽  
Vol 37 (2) ◽  
pp. 116-121 ◽  
Author(s):  
Yoshihiro Sato ◽  
Takeshi Asoh ◽  
Yoshiaki Honda ◽  
Yukiko Fujimatsu ◽  
Itsuro Higuchi ◽  
...  
Keyword(s):  
Pulmonary Emphysema ◽  
Chronic Pulmonary Emphysema

Blood Ammonia in Chronic Pulmonary Emphysema

1959 ◽  
Vol 261 (27) ◽  
pp. 1369-1373 ◽  
Author(s):  
R. Dutton ◽  
W. Nicholas ◽  
C. J. Fisher ◽  
A. D. Renzetti
Keyword(s):  
Pulmonary Emphysema ◽  
Blood Ammonia ◽  
Chronic Pulmonary Emphysema

Ventilatory drive in chronic pulmonary emphysema

1955 ◽  
Vol 19 (4) ◽  
pp. 533-548 ◽  
Author(s):  
A.P. Fishman ◽  
P. Samet ◽  
André Cournand
Keyword(s):  
Pulmonary Emphysema ◽  
Ventilatory Drive ◽  
Chronic Pulmonary Emphysema
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