Tyrosine Prevents the Diminished Male Copulatory Behavior in Prenatally Stressed Male Rats

Author(s):  
Tomi Ohkawa ◽  
Kiyoshi Arai ◽  
Shouichi Okinaga ◽  
Franziska G�tz ◽  
Fritz Stahl ◽  
...  
1998 ◽  
Vol 274 (1) ◽  
pp. R243-R247 ◽  
Author(s):  
Yoshikazu Sato ◽  
Hiroki Horita ◽  
Toshie Kurohata ◽  
Hideki Adachi ◽  
Taiji Tsukamoto

We investigated the influence of the extracellular nitric oxide (NO) level on male copulatory behavior. We confirmed the changes of nitrite ([Formula: see text]) and nitrate ([Formula: see text]) in the medial preoptic area (MPOA) by administration of the NO precursorl-arginine (l-Arg, 10 mM) or the NO synthase inhibitor N G-monomethyl-l-arginine (l-NMMA, 10 mM) via a dialysis probe. [Formula: see text] and[Formula: see text] were measured simultaneously by an in vivo microdialysis method coupled with the Griess reaction.l-Arg induced significant elevations of extracellular [Formula: see text]and [Formula: see text].l-NMMA significantly reduced[Formula: see text] and[Formula: see text] levels. We observed male copulatory behavior during infusion ofl-Arg orl-NMMA. The mount rate of male rats significantly increased during infusion ofl-Arg in the MPOA. Administration of l-NMMA reduced the mount rate. These findings suggested that the elevation of extracellular NO in the MPOA facilitates male copulatory behavior of rats, whereas the decrease of NO reduces their copulatory behavior.


1988 ◽  
Vol 43 (3) ◽  
pp. 351-357 ◽  
Author(s):  
George J. Bloch ◽  
Alex M. Babcock ◽  
Roger A. Gorski ◽  
P.E. Micevych

1973 ◽  
Vol 2 (4) ◽  
pp. 237-239 ◽  
Author(s):  
Deirdre V. Lovecky ◽  
Donald A. Dewsbury

1994 ◽  
Vol 43 (3) ◽  
pp. 427-431 ◽  
Author(s):  
Atsushi TOHEI ◽  
Toru R. SAITO ◽  
Ryoji HOKAO ◽  
Sen-ichi FURUDATE ◽  
Kazuaki W. TAKAHASHI

1999 ◽  
Vol 50 (3) ◽  
pp. 193-199 ◽  
Author(s):  
Reuben W Rhees ◽  
Hamid N Al-Saleh ◽  
Edward W Kinghorn ◽  
Donovan E Fleming ◽  
Edwin D Lephart

Sign in / Sign up

Export Citation Format

Share Document