Nutritional Control of Brain Neurotransmitter Synthesis and Its Implications

2015 ◽  
pp. 39-53
Author(s):  
David V. M. Ashley
Keyword(s):  
Brain Neurotransmitter ◽  
Neurotransmitter Synthesis

scholarly journals High-fat diet-induced obesity and impairment of brain neurotransmitter pool

2020 ◽  
Vol 11 (1) ◽  
pp. 147-160
Author(s):  
Ranyah Shaker M. Labban ◽  
Hanan Alfawaz ◽  
Ahmed T. Almnaizel ◽  
Wail M. Hassan ◽  
Ramesa Shafi Bhat ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Brain Tissue ◽  
High Fat Diet ◽  
Density Lipoprotein ◽  
Obese Group ◽  
Control Group ◽  
High Fat ◽  
Brain Neurotransmitter ◽  
The Brain ◽  
Lean Group

AbstractObesity and the brain are linked since the brain can control the weight of the body through its neurotransmitters. The aim of the present study was to investigate the effect of high-fat diet (HFD)-induced obesity on brain functioning through the measurement of brain glutamate, dopamine, and serotonin metabolic pools. In the present study, two groups of rats served as subjects. Group 1 was fed a normal diet and named as the lean group. Group 2 was fed an HFD for 4 weeks and named as the obese group. Markers of oxidative stress (malondialdehyde, glutathione, glutathione-s-transferase, and vitamin C), inflammatory cytokines (interleukin [IL]-6 and IL-12), and leptin along with a lipid profile (cholesterol, triglycerides, high-density lipoprotein, and low-density lipoprotein levels) were measured in the serum. Neurotransmitters dopamine, serotonin, and glutamate were measured in brain tissue. Fecal samples were collected for observing changes in gut flora. In brain tissue, significantly high levels of dopamine and glutamate as well as significantly low levels of serotonin were found in the obese group compared to those in the lean group (P > 0.001) and were discussed in relation to the biochemical profile in the serum. It was also noted that the HFD affected bacterial gut composition in comparison to the control group with gram-positive cocci dominance in the control group compared to obese. The results of the present study confirm that obesity is linked to inflammation, oxidative stress, dyslipidemic processes, and altered brain neurotransmitter levels that can cause obesity-related neuropsychiatric complications.

scholarly journals Housing and road transport modify the brain neurotransmitter systems of pigs: Do pigs raised in different conditions cope differently with unknown environments?

PLoS ONE ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. e0210406 ◽  
Author(s):  
Laura Arroyo ◽  
Daniel Valent ◽  
Ricard Carreras ◽  
Raquel Peña ◽  
Josefa Sabrià ◽  
...  
Keyword(s):  
Road Transport ◽  
Neurotransmitter Systems ◽  
Unknown Environments ◽  
Brain Neurotransmitter ◽  
The Brain

Room E, 10/16/2000 2: 00 PM - 4: 00 PM (PS) Effect of Dexmedetomidine on Brain Neurotransmitter-Concentration during Cerebral Ischemia in the Rat 

2000 ◽  
Vol 93 (3A) ◽  
pp. A-719
Author(s):  
Kristin Engelhard ◽  
Christian Werner ◽  
Oliver Mollenberg ◽  
Hilkea Rosenbrock ◽  
Eberhard Kochs
Keyword(s):  
Cerebral Ischemia ◽  
Brain Neurotransmitter

Regulation of enzymes responsible for neurotransmitter synthesis and degradation in cultured rat sympathetic neurons

1983 ◽  
Vol 100 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Jean-Paul Swerts ◽  
Agathe Le Van Thai ◽  
Annette Vigny ◽  
Michel J. Weber
Keyword(s):  
Sympathetic Neurons ◽  
Neurotransmitter Synthesis ◽  
Synthesis And Degradation
Sign in / Sign up

Export Citation Format

Share Document