Portal-Systemic Encephalopathy in Dogs: Changes in Brain GABA Receptors and Neurochemical Correlates

Author(s):  
M. Baraldi ◽  
M. L. Zeneroli ◽  
E. Ventura ◽  
G. Pinelli ◽  
P. Ricci ◽  
...  
2021 ◽  
Vol 206 (Supplement 3) ◽  
Author(s):  
Masaki Yamamoto ◽  
Takahiro Shimizu ◽  
Suo Zou ◽  
Shogo Shimizu ◽  
Youichirou Higashi ◽  
...  

2000 ◽  
Vol 38 (2) ◽  
pp. 193-198 ◽  
Author(s):  
Martin L Kram ◽  
Gerald L Kramer ◽  
Mark Steciuk ◽  
Patrick J Ronan ◽  
Frederick Petty

Nitric Oxide ◽  
2020 ◽  
Vol 104-105 ◽  
pp. 44-50
Author(s):  
Masaki Yamamoto ◽  
Takahiro Shimizu ◽  
Suo Zou ◽  
Shogo Shimizu ◽  
Youichirou Higashi ◽  
...  

Author(s):  
Erwan Sallard ◽  
Diane Letourneur ◽  
Pascal Legendre

AbstractGABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and diverse roles GABAA receptors play in the regulation of neuronal communication and the functioning of the brain. GABAA receptors have complex electrophysiological properties that enable them to mediate different types of currents such as phasic and tonic inhibitory currents. Their activity is finely regulated by membrane voltage, phosphorylation and several ions. GABAA receptors are pentameric and are assembled from a diverse set of subunits. They are subdivided into numerous subtypes, which differ widely in expression patterns, distribution and electrical activity. Substantial variations in macroscopic neural behavior can emerge from minor differences in structure and molecular activity between subtypes. Therefore, the diversity of GABAA receptors widens the neuronal repertoire of responses to external signals and contributes to shaping the electrical activity of neurons and other cell types.


2020 ◽  
Vol 177 (17) ◽  
pp. 3924-3940
Author(s):  
Christopher Henry ◽  
Thierry Cens ◽  
Pierre Charnet ◽  
Catherine Cohen‐Solal ◽  
Claude Collet ◽  
...  

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