Is Brain Asymmetry the Rule or the Exception? Morphological Considerations on Lower Vertebrates

2015 ◽  
pp. 20-29 ◽  
Author(s):  
Milena Kemali
Keyword(s):  
Brain Asymmetry ◽  
Lower Vertebrates

Relationships between Frontal Brain Asymmetry and Immune Function

1999 ◽  
Author(s):  
Ted Robles ◽  
Jessica Malmstadt ◽  
Jon Kabat-Zinn ◽  
Daniel Muller ◽  
Richard Davidson
Keyword(s):  
Immune Function ◽  
Brain Asymmetry ◽  
Frontal Brain

ACTION OF ENZYME DIGESTED PITUITARY GLANDS OF THE SKIPPER-FROG ON THE OVULATION OF THE SAME

1960 ◽  
Vol XXXIII (II) ◽  
pp. 255-260 ◽  
Author(s):  
L. S. Ramaswami ◽  
A. B. Lakshman
Keyword(s):  
Pituitary Gland ◽  
Constant Temperature ◽  
Constant Temperature Bath ◽  
Predominant Role ◽  
Lower Vertebrates ◽  
Pituitary Glands ◽  
Stimulating Factor

ABSTRACT By using enzymes, the gonadotrophic factors in the skipper-frog pituitary glands have been selectively inactivated or destroyed. By incubating a known number of pituitary gland homogenate with ptyalin in a constant temperature bath for 5–6 h the follicle-stimulating factor is inactivated; with trypsin or pepsin, the luteinizing factor is inactivated. Bioassay on gravid skipper-frogs indicate that the ptyalin digested homogenate brings about profuse spawning while the trypsin or pepsin digested homogenates do not. When a combination of ptyalin digested and trypsin digested homogenates is injected into fresh gravid skipper-frogs, poor spawning is brought about. These experiments show that the luteinizing factor alone brings about more profuse spawning than when it is combined with the follicle-stimulating factor. It is likely, therefore, that in the lower vertebrates the luteinizing factor of the pituitary gland plays a more predominant role. The exact proportions in which the different dosages for the control and test animals are administered are also tabulated.

scholarly journals Cardiac regeneration: epicardial mediated repair

2015 ◽  
Vol 282 (1821) ◽  
pp. 20152147 ◽  
Author(s):  
Teresa Kennedy-Lydon ◽  
Nadia Rosenthal
Keyword(s):  
Stem Cells ◽  
Endothelial Cells ◽  
Cardiac Fibroblasts ◽  
Cardiac Regeneration ◽  
Repair Process ◽  
Regenerative Process ◽  
Cardiac Stem Cell ◽  
Cardiomyocyte Proliferation ◽  
Lower Vertebrates

The hearts of lower vertebrates such as fish and salamanders display scarless regeneration following injury, although this feature is lost in adult mammals. The remarkable capacity of the neonatal mammalian heart to regenerate suggests that the underlying machinery required for the regenerative process is evolutionarily retained. Recent studies highlight the epicardial covering of the heart as an important source of the signalling factors required for the repair process. The developing epicardium is also a major source of cardiac fibroblasts, smooth muscle, endothelial cells and stem cells. Here, we examine animal models that are capable of scarless regeneration, the role of the epicardium as a source of cells, signalling mechanisms implicated in the regenerative process and how these mechanisms influence cardiomyocyte proliferation. We also discuss recent advances in cardiac stem cell research and potential therapeutic targets arising from these studies.

Biological Sciences: N-Terminal Sequences of Immunoglobulin Heavy and Light Chains from Three Species of Lower Vertebrates

Nature ◽  
1970 ◽  
Vol 228 (5275) ◽  
pp. 991-992 ◽  
Author(s):  
RONALD T. ACTON ◽  
PETER F. WEINHEIMER ◽  
MICHAEL WOLCOTT ◽  
E. EDWARD EVANS ◽  
J. C. BENNETT
Keyword(s):  
Biological Sciences ◽  
Light Chains ◽  
Lower Vertebrates

scholarly journals The genetic architecture of structural left–right asymmetry of the human brain

2021 ◽  
Author(s):  
Zhiqiang Sha ◽  
Dick Schijven ◽  
Amaia Carrion-Castillo ◽  
Marc Joliot ◽  
Bernard Mazoyer ◽  
...  
Keyword(s):  
Brain Asymmetry ◽  
Functional Enrichment ◽  
Brain Organization ◽  
Genome Wide ◽  
Brain Expression ◽  
Using Data ◽  
Left Right Asymmetry ◽  
The Uk ◽  
Subcortical Volume

AbstractLeft–right hemispheric asymmetry is an important aspect of healthy brain organization for many functions including language, and it can be altered in cognitive and psychiatric disorders. No mechanism has yet been identified for establishing the human brain’s left–right axis. We performed multivariate genome-wide association scanning of cortical regional surface area and thickness asymmetries, and subcortical volume asymmetries, using data from 32,256 participants from the UK Biobank. There were 21 significant loci associated with different aspects of brain asymmetry, with functional enrichment involving microtubule-related genes and embryonic brain expression. These findings are consistent with a known role of the cytoskeleton in left–right axis determination in other organs of invertebrates and frogs. Genetic variants associated with brain asymmetry overlapped with those associated with autism, educational attainment and schizophrenia. Comparably large datasets will likely be required in future studies, to replicate and further clarify the associations of microtubule-related genes with variation in brain asymmetry, behavioural and psychiatric traits.

IODINE METABOLISM IN LOWER VERTEBRATES

2006 ◽  
Vol 86 (2) ◽  
pp. 316-353 ◽  
Author(s):  
J. Leloup ◽  
M. Fontaine
Keyword(s):  
Lower Vertebrates ◽  
Iodine Metabolism

scholarly journals Low‐molecular‐weight phosphotyrosyl protein phosphatase expression in brain of chicken and some lower vertebrates

2002 ◽  
Vol 69 (2) ◽  
pp. 97-102
Author(s):  
Livia Lucentini ◽  
Antonella Angiolillo ◽  
Emanuela Varasano ◽  
Fausto Panara
Keyword(s):  
Molecular Weight ◽  
Protein Phosphatase ◽  
Low Molecular Weight ◽  
Lower Vertebrates
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