The Importance of Bone Marrow Biopsy in Myelodysplastic Disorders

2015 ◽  
pp. 31-40
Author(s):  
G. Tricot ◽  
C. De Wolf-Peelers ◽  
R. Vlietinck ◽  
R. L. Verwilghen
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Biopsy

Bone marrow biopsy in children: A study of 111 patients

1979 ◽  
Vol 6 (1) ◽  
pp. 57-64 ◽  
Author(s):  
C. Cozzutto ◽  
B. de Bernardi ◽  
A. Comelli ◽  
M. Guarino
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Biopsy

A new model to predict remission status in AML patients based on day 14 bone marrow biopsy

2016 ◽  
Vol 46 ◽  
pp. 69-73 ◽  
Author(s):  
Maxim Norkin ◽  
Myron Chang ◽  
Qi An ◽  
Helen Leather ◽  
Lakshmikanth Katragadda ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Biopsy ◽  
New Model ◽  
Remission Status

scholarly journals Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Yuta Inagawa ◽  
Yukiko Komeno ◽  
Satoshi Saito ◽  
Yuji Maenohara ◽  
Tetsuro Yamagishi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Promyelocytic Leukemia ◽  
Bone Marrow Biopsy ◽  
Gastric Fluid ◽  
Promyelocytic Leukemia ◽  
Consolidation Therapy ◽  
Bone Marrow Fibrosis ◽  
All Trans Retinoic Acid ◽  
Phlegmonous Gastritis ◽  
Marrow Fibrosis

A 34-year-old woman was diagnosed with acute promyelocytic leukemia. Chemotherapy was administered following the JALSG APL204 protocol. Induction therapy with all-trans retinoic acid resulted in complete remission on day 49. She developed coccygeal pain from day 18, which spread to the spine and cheekbones and lasted 5 weeks. She had similar bone pain on days 7–10 of the first consolidation therapy and on days 4–12 of the second consolidation therapy. Oral loxoprofen was prescribed for pain relief. On day 33 of the third consolidation, white blood cell and neutrophil counts were 320/μL and 20/μL, respectively. After she developed epigastralgia and hematemesis, she developed septic shock. Gastroendoscopy revealed markedly thickened folds and diffusely damaged mucosa with blood oozing. Computed tomography revealed thickened walls of the antrum and the pylorus. Despite emergency treatments, she died. Bacterial culture of the gastric fluid yielded Enterobacter cloacae and enterococci growth. Collectively, she was diagnosed with phlegmonous gastritis. Retrospective examination of serial bone marrow biopsy specimens demonstrated progressive bone marrow fibrosis, which may have caused prolonged myelosuppression. Thus, evaluation of bone marrow fibrosis by bone marrow biopsy after each treatment cycle might serve as a predictor of persistent myelosuppression induced by chemotherapy.

scholarly journals Inadvertent arterial & venous injury by bone marrow biopsy needle: case report on rescue embolization techniques

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Chris Siu-Chun Tsai ◽  
Simon Chun-Ho Yu
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Biopsy ◽  
Vascular Injury ◽  
Iliac Artery ◽  
Morbidity And Mortality ◽  
Biopsy Needle ◽  
Venous Injury ◽  
Patient Morbidity ◽  
Internal Iliac ◽  
Life Threatening

Abstract Background Bone marrow biopsy is a common medical procedure for diagnosis and characterization of haematological diseases. It is generally regarded as a safe procedure with low rate of major complications. Inadvertent vascular injury is however an uncommon but important complication of bone marrow biopsy procedure. The knowledge of a safe and effective embolization method is crucial for interventional radiologists to reduce significant patient morbidity and mortality, shall such inadvertent vascular injury occurs. Case presentation Bedside bone marrow biopsy was performed for an elderly gentleman to evaluate for his underlying acute leukaemia. Biopsy needle inadvertently injured the internal iliac artery and vein during the procedure. Coil embolization was carefully performed across injured arterial segment via the culprit biopsy needle until contrast cessation. Concomitant venous injury was subsequently confirmed on angiography when the needle was withdrawn for a short distance from the iliac artery. This venous injury was tackled by further withdrawing the biopsy needle to distal end of the bone marrow tract for tract embolization with coils and gelatin sponges. High caution was made to avoid coil dislodgement into the iliac vein, to prevent pulmonary embolism. Patient was clinically stable throughout the procedure. Post-procedure contrast CT shows no pelvic haematoma or contrast extravasation. Conclusions This case illustrates rescue embolization techniques for rare life-threatening concomitant internal iliac arterial and venous injuries by a bone marrow biopsy needle. Interventional radiologists can play an important role in carrying out precise embolization to avoid significant patient morbidity and mortality in the case of life-threatening haemorrhage.

scholarly journals Safe and successful bone marrow biopsy: An anatomical and CT-based cadaver study

2014 ◽  
Vol 89 (10) ◽  
pp. 943-946 ◽  
Author(s):  
Bhavana Konda ◽  
Swati Pathak ◽  
Inga Edwin ◽  
Priti Mishall ◽  
Sherry A. Downie ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Biopsy ◽  
Cadaver Study

Histopathological and immunohistochemical evaluation of bone marrow biopsy in myelodysplastic syndromes

2013 ◽  
Vol 2 (3) ◽  
pp. 219-228
Author(s):  
Emanuela Boveri ◽  
Giorgio Croci ◽  
Umberto Gianelli ◽  
Marcello Gambacorta ◽  
Giuseppe Isimbaldi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Biopsy ◽  
Myelodysplastic Syndromes

Traumatic superior gluteal artery pseudoaneurysm following a bone marrow biopsy

2016 ◽  
Vol 46 (3) ◽  
pp. 374-375 ◽  
Author(s):  
I. R. Caldwell ◽  
B. T. Buckley ◽  
R. Rajagopal ◽  
R. Doocey ◽  
L. Pemberton
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Biopsy ◽  
Superior Gluteal Artery ◽  
Artery Pseudoaneurysm
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