Tiaprofenic Acid in Osteoarthritis of the Hip and Knee

2015 ◽  
pp. 20-22
Author(s):  
J. M. Poal Ballarin ◽  
P. Fernandez de Vallado ◽  
J. J. Molina Soto
Keyword(s):  
Tiaprofenic Acid ◽  
Osteoarthritis Of The Hip

Dual-Energy X-Ray Absorptiometric Densitometry in Osteoarthritis of the Hip

1997 ◽  
Vol 38 (4) ◽  
pp. 539-542
Author(s):  
Klaus Preidler ◽  
L. S. White ◽  
J. Tashkin ◽  
C. O. McDaniel ◽  
J. Brossmann ◽  
...  
Keyword(s):  
Dual Energy ◽  
Osteoarthritis Of The Hip ◽  
X Ray

Tiaprofenic acid

1994 ◽  
Vol &NA; (492) ◽  
pp. 12
Author(s):  
&NA;
Keyword(s):  
Tiaprofenic Acid

Total Hip Arthroplasty for Avascular Necrosis and Degenerative Osteoarthritis of the Hip

1997 ◽  
Vol 341 ◽  
pp. 62???68 ◽  
Author(s):  
Theodore A. Xenakis ◽  
Alexandros E. Beris ◽  
Konstantinos K. Malizos ◽  
Theodosios Koukoubis ◽  
John Gelalis ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Avascular Necrosis ◽  
Hip Arthroplasty ◽  
Osteoarthritis Of The Hip ◽  
Degenerative Osteoarthritis ◽  
Total Hip

scholarly journals Thiophene-Based Compounds with Potential Anti-Inflammatory Activity

2021 ◽  
Vol 14 (7) ◽  
pp. 692
Author(s):  
Ryldene Marques Duarte da Cruz ◽  
Francisco Jaime Bezerra Mendonça-Junior ◽  
Natália Barbosa de Mélo ◽  
Luciana Scotti ◽  
Rodrigo Santos Aquino de Araújo ◽  
...  
Keyword(s):  
Inflammatory Diseases ◽  
Structural Characteristics ◽  
Tiaprofenic Acid ◽  
Inflammatory Activity ◽  
Drug Candidates ◽  
Biological Target ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Privileged Structures

Rheumatoid arthritis, arthrosis and gout, among other chronic inflammatory diseases are public health problems and represent major therapeutic challenges. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most prescribed clinical treatments, despite their severe side effects and their exclusive action in improving symptoms, without effectively promoting the cure. However, recent advances in the fields of pharmacology, medicinal chemistry, and chemoinformatics have provided valuable information and opportunities for development of new anti-inflammatory drug candidates. For drug design and discovery, thiophene derivatives are privileged structures. Thiophene-based compounds, like the commercial drugs Tinoridine and Tiaprofenic acid, are known for their anti-inflammatory properties. The present review provides an update on the role of thiophene-based derivatives in inflammation. Studies on mechanisms of action, interactions with receptors (especially against cyclooxygenase (COX) and lipoxygenase (LOX)), and structure-activity relationships are also presented and discussed. The results demonstrate the importance of thiophene-based compounds as privileged structures for the design and discovery of novel anti-inflammatory agents. The studies reveal important structural characteristics. The presence of carboxylic acids, esters, amines, and amides, as well as methyl and methoxy groups, has been frequently described, and highlights the importance of these groups for anti-inflammatory activity and biological target recognition, especially for inhibition of COX and LOX enzymes.

scholarly journals Role of radiography in predicting progression of osteoarthritis of the hip: prospective cohort study

BMJ ◽  
2005 ◽  
Vol 330 (7501) ◽  
pp. 1183 ◽  
Author(s):  
Max Reijman ◽  
J M W Hazes ◽  
H.A.P Pols ◽  
R M D Bernsen ◽  
B W Koes ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Osteoarthritis Of The Hip

Intra-Articular Steroid Injection for Pain Relief in Osteoarthritis of the Hip

2001 ◽  
Vol 23 (3) ◽  
pp. 113-115 ◽  
Author(s):  
M.A. Wajid ◽  
R. Kumar ◽  
M.R.S. C M E Lennox
Keyword(s):  
Pain Relief ◽  
Steroid Injection ◽  
Osteoarthritis Of The Hip
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