Carbon Tetrachloride-Induced Block of Hepatic Lipoprotein Secretion: Studies of the Pathogenesis Using Isolated Rat Hepatocytes

Author(s):  
M. U. Dianzani ◽  
G. Poli
1979 ◽  
Vol 178 (2) ◽  
pp. 509-512 ◽  
Author(s):  
E Gravela ◽  
E Albano ◽  
M U Dianzani ◽  
G Poli ◽  
T F Slater

The effects of carbon tetrachloride on protein and lipoprotein secretion, and on lipid peroxidation, have been investigated in isolated rat hepatocytes. It was found that although the free-radical scavenger promethazine completely suppressed the increased peroxidation produced by carbon tetrachloride, it had no effect on the inhibitory action of carbon tetrachloride on lipoprotein secretion. In consequence, the latter effect of carbon tetrachloride does not appear to be mediated through a peroxidative stage.


1988 ◽  
Vol 153 (2) ◽  
pp. 591-597 ◽  
Author(s):  
Giuseppe Poli ◽  
Emanuele Albano ◽  
Mario U. Dianzani ◽  
Edon Melloni ◽  
Sandro Pontremoli ◽  
...  

1997 ◽  
Vol 103 (3) ◽  
pp. 213-224 ◽  
Author(s):  
Chen Wua ◽  
Chika Miyagawaa ◽  
David Opare Kennedya ◽  
Yoshihisa Yanob ◽  
Shuzo Otanib ◽  
...  

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