Differentiation and Anaplasia in Central Neuroepithelial Tumors

2015 ◽  
pp. 32-48 ◽  
Author(s):  
Lucien J. Rubinstein ◽  
Mary M. Herman ◽  
Scott R. VandenBerg
Keyword(s):  
Neuroepithelial Tumors

Ganglioside patterns in neuroepithelial tumors of childhood

2000 ◽  
Vol 22 (3) ◽  
pp. 196-198 ◽  
Author(s):  
Xiao Li Pan ◽  
Tatsuro Izumi ◽  
Hiroshi Yamada ◽  
Kensuke Akiyoshi ◽  
Souichi Suenobu ◽  
...  
Keyword(s):  
Neuroepithelial Tumors

Two Cases of Dysembryoplastic Neuroepithelial Tumors With Intractable Complex Partial Seizures

1997 ◽  
Vol 12 (1) ◽  
pp. 67-70 ◽  
Author(s):  
Masayuki Itoh ◽  
Takehito Morita ◽  
Sadataka Houdou ◽  
Shinsuke Kato ◽  
Eisaku Ohama ◽  
...  
Keyword(s):  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Neuroepithelial Tumors ◽  
Dysembryoplastic Neuroepithelial Tumors

scholarly journals Dysembryoplastic neuroepithelial tumors and cognitive outcome

Cancer ◽  
2010 ◽  
Vol 116 (23) ◽  
pp. 5461-5469 ◽  
Author(s):  
Ibrahim Qaddoumi ◽  
David W. Ellison ◽  
E. Brannon Morris ◽  
Alberto Broniscer ◽  
Frederick Boop ◽  
...  
Keyword(s):  
Cognitive Outcome ◽  
Neuroepithelial Tumors ◽  
Dysembryoplastic Neuroepithelial Tumors

484 Sex steroid receptors in 53 human CNS neuroepithelial tumors

1983 ◽  
Vol 19 ◽  
pp. 166
Author(s):  
J. Hassoun ◽  
P.M. Martin ◽  
R.P. Vigouroux ◽  
M. Toga ◽  
M. Moguilewsky ◽  
...  
Keyword(s):  
Steroid Receptors ◽  
Sex Steroid ◽  
Neuroepithelial Tumors ◽  
Sex Steroid Receptors

scholarly journals Construction and Clinical Verification of Cytoplasm Protein GFAP as Circulating Tumor Cell Separation target for Pediatric Neuroepithelial Tumors

2020 ◽  
Author(s):  
Yang Zhao ◽  
Feng Jiang ◽  
Qinhua Wang ◽  
Baocheng Wang ◽  
Yipeng Han ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Detection System ◽  
Invasive Procedure ◽  
Circulating Tumor Cell ◽  
Immunofluorescence Assay ◽  
Good Choice ◽  
Neuroepithelial Tumors ◽  
Prediction Function

Abstract BACKGROUND: Pediatric Neuroepithelial Tumors (NT) are one of the most prevalent diseases among children. Developing a highly efficient cerebrospinal fluid (CSF) detection system with diagnosis and prediction function is very important. Circulating tumor cell (CTC) in CSF is a good choice. In contrast to the past use of epithelial EpCAM as CTC separation target, an cytoplasm protein of GFAP antibody was first selected to construct highly-sensitive immunomagnetic liposomes (IMLs). The validation and efficiency of this system in capturing CTCs for NT were measured both in vitro and in vivo. The associations between the numbers of CTCs in patients with their clinical characteristics were further analyzed. RESULTS: Our data show that CTCs can be successfully isolated from CSF and blood samples from 29 children with NT. The numbers of CTCs in CSF were significantly higher than those in blood. The level of CTCs in CSF was related to the type and location of the tumor rather than its stage. Genetic testing in GFAP CTC-DNA by sanger sequencing, q-PCR and NGS methods indicated that the isolated CTCs (GFAP+/EGFR+) are the related tumor cell. For example, the high expression of NPR3 gene in CSF CTC was consistant with tumor tissue. CONCLUSIONS: GFAP-IML isolation of CTCs, combined with an EGFR immunofluorescence assay of antitumor marker, can serve as a brand-new method for the identification of CTCs for brain tumors. Via lumbar puncture, a minimally invasive procedure, this technique can be clinically significant in diagnosis and efficacy assessments of pediatric NT.

Dysembryoplastic Neuroepithelial Tumors 1

2021 ◽  
Author(s):  
Jai Patel ◽  
Daniel Gewolb, MD ◽  
Joseph Giampa
Keyword(s):  
Neuroepithelial Tumors ◽  
Dysembryoplastic Neuroepithelial Tumors
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