The Relationship of Dietary Calcium to Zinc Metabolism in Pigs

1958 ◽  
Vol 17 (3) ◽  
pp. 886-892 ◽  
Author(s):  
H. W. Newland ◽  
D. E. Ullrey ◽  
J. A. Hoefer ◽  
R. W. Luecke
Keyword(s):  
Dietary Calcium ◽  
Zinc Metabolism ◽  
Relationship Of ◽  
The Relationship

scholarly journals Nitrogen, Iron and Zinc Acquisition: Key Nutrients to Aspergillus fumigatus Virulence

2021 ◽  
Vol 7 (7) ◽  
pp. 518
Author(s):  
Uxue Perez-Cuesta ◽  
Xabier Guruceaga ◽  
Saioa Cendon-Sanchez ◽  
Eduardo Pelegri-Martinez ◽  
Fernando L. Hernando ◽  
...  
Keyword(s):  
Aspergillus Fumigatus ◽  
Opportunistic Pathogen ◽  
Zinc Metabolism ◽  
Wide Field ◽  
Regulation Process ◽  
Number Of Genes ◽  
Iron And Zinc ◽  
Fungal Nutrition

Aspergillus fumigatus is a ubiquitous soil decomposer and an opportunistic pathogen that is characterized by its large metabolic machinery for acquiring nutrients from media. Lately, an ever-increasing number of genes involved in fungal nutrition has been associated with its virulence. Of these, nitrogen, iron, and zinc metabolism-related genes are particularly noteworthy, since 78% of them have a direct implication in virulence. In this review, we describe the sensing, uptake and regulation process of the acquisition of these nutrients, the connections between pathways and the virulence-implicated genes. Nevertheless, only 40% of the genes mentioned in this review have been assayed for roles in virulence, leaving a wide field of knowledge that remains uncertain and might offer new therapeutic and diagnostic targets.

scholarly journals Zinc Metabolism and Requirements

2001 ◽  
Vol 22 (2) ◽  
pp. 126-132 ◽  
Author(s):  
Michael Hambidge ◽  
Nancy F. Krebs
Keyword(s):  
Zinc Metabolism

Zinc Metabolism in Non-insulin Dependent Diabetes Mellitus

1997 ◽  
Vol 11 (2) ◽  
pp. 65-70 ◽  
Author(s):  
A.M. Rauscher ◽  
S.J. Fairweather-Tait ◽  
P.D.G. Wilson ◽  
S. Gorrick ◽  
R. Greenwood
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Dependent Diabetes Mellitus ◽  
Insulin Dependent Diabetes ◽  
Dependent Diabetes Mellitus ◽  
Zinc Metabolism ◽  
Insulin Dependent

EFFECT OF RENAL TRANSPLANTATION ON ZINC METABOLISM AND TASTE ACUITY IN UREMIA

1984 ◽  
Vol 38 (6) ◽  
pp. 599-602 ◽  
Author(s):  
A Prospective Study ◽  
Sudesh K. Mahajan ◽  
Judith Abraham ◽  
Stephen D. Migdal ◽  
Daoud K. Abu-Hamdan ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Zinc Metabolism

The interplay between iron and zinc metabolism in Aspergillus fumigatus

2009 ◽  
Vol 46 (9) ◽  
pp. 707-713 ◽  
Author(s):  
Sabiha Yasmin ◽  
Beate Abt ◽  
Markus Schrettl ◽  
Tarek A.A. Moussa ◽  
Ernst R. Werner ◽  
...  
Keyword(s):  
Aspergillus Fumigatus ◽  
Zinc Metabolism ◽  
Iron And Zinc

Enteropathic acrodermatitis in children

2021 ◽  
Vol 11 (2) ◽  
pp. 21-28
Author(s):  
V.P. Novikova ◽  
◽  
A.A. Pokhlebkina ◽  
D.V. Zaslavsky ◽  
A.I. Khavkin ◽  
...  
Keyword(s):  
Zinc Deficiency ◽  
Topical Therapy ◽  
Clinical Manifestations ◽  
Skin Lesions ◽  
Knee Joints ◽  
Zinc Metabolism ◽  
Plasma Zinc ◽  
Significant Treatment ◽  
Zinc Concentrations ◽  
Erythematous Plaques

Enteropathic acrodermatitis is a rare hereditary form of zinc deficiency, characterized by periorial and acral dermatitis, alopecia and diarrhea. Refers to congenital disorders of zinc metabolism, inherited as an autosomal recessive disease resulting from mutations in the gene for the zinc transporter SLC39A4. The prevalence ranges from 1 to 9:1,000,000, with an overall incidence of 1:500,000 newborns. The disease usually manifests itself in infancy, within a few weeks of stopping breastfeeding and switching the baby to a cow's milk-based formula, or in the first days of life if artificially fed from birth. The classical clinical manifestations of acrodermatitis enteropathic are characterized by the triad: acral and periofital dermatitis, alopecia and diarrhea, but all three signs together occur only in 20% of cases. Diarrhea may develop concurrently with skin symptoms, may precede or occur later. Characteristic signs of skin lesions include sharply demarcated, dry, scaly erythematous plaques or edematous foci with vesicles and pustules on the skin of the elbow and knee joints, distal extremities, genitals, in the inguinal folds, which are usually symmetrically distributed, have sharp boundaries and irregular outlines. The course of the skin syndrome is long, as it progresses, non-healing erosive and ulcerative areas appear. Plasma zinc deficiency is the gold standard for diagnosis. Most infants with AE have low plasma zinc concentrations (<500 mcg/L or <50 mcg/dl), but a level of less than 70 mcg/L on an empty stomach or less than 65 mcg/dl in older non-dieting children is considered diagnostically significant. Treatment for this disease usually includes enteral or parenteral zinc administration, at a dose of 1-3 mg/kg/day. for elemental zinc. A clinical response is observed within 5–10 days. Supportive zinc therapy is necessary throughout the patient's life, although periods of remission have been reported. Topical therapy is also used: Dexpanthenol in the form of a cream, applied 3 times a day in the area of dermatitis, can enhance re-epithelialization. There is no significant evidence of improvement with topical zinc application. No activity restrictions are required for patients with acrodermatitis enteropathic. Key words: zinc deficiency, enteropathic acrodermatitis, children

scholarly journals A comparison of the short-term kinetics of zinc metabolism in women during fasting and following a breakfast meal

1998 ◽  
Vol 80 (4) ◽  
pp. 363-370 ◽  
Author(s):  
Nicola M. Lowe ◽  
Leslie R. Woodhouse ◽  
Janet C. King
Keyword(s):  
Energy Content ◽  
Compartment Model ◽  
Zinc Metabolism ◽  
Short Term ◽  
Compartment System ◽  
Breakfast Meal ◽  
Physiological Importance ◽  
Two Compartment Model ◽  
Zn Concentration ◽  
Kinetics Of

The physiological importance and mechanism of the postprandial fall in plasma Zn concentration is not well understood. In order to gain further information on this apparent redistribution of plasma Zn, a stable isotope, 70Zn, was used to study the effect of a breakfast meal on plasma Zn kinetics. Nine women participated in two trials, a fasting trial and a breakfast-meal trial; five of the women participated in a third trial in which the energy content of the breakfast meal was doubled. At each trial, 0.1mg of 70Zn was infused intravenously, and the plasma disappearance of the isotope was analysed using a two-compartment model of Zn kinetics. Plasma Zn concentration fell significantly following the two trials in which the subjects were given meals, reaching low points that were 13 and 19 %, respectively, below concentrations at comparable times during the fasting trial. Kinetic analysis revealed that after the doubled breakfast meal there was a significant fall (P < 0.007) in the size of the most rapidly turning over Zn pool (pool (a)) from 2.90 (se 0.13)mg in the fasting state to 2.47 (se 0.14) mg postprandially. The fractional turnover rate of pool (a) to other extravascular Zn pools, i.e. outside the two-compartment system, was also significantly elevated after the doubled breakfast meal (P < 0.05). These results suggest that the decline in plasma Zn concentration following a meal is due to a redistribution of Zn from the plasma to other more slowly turning over extravascular pools that may be involved in the assimilation and metabolism of fuels following food intake.

Sign in / Sign up

Export Citation Format

Share Document