Preliminary Observations on the Laboratory Markers of Cell-Mediated Immunity in Patients Transferring from Hemodialysis to Continuous Ambulatory Peritoneal Dialysis1

Author(s):  
Satwant Singh ◽  
Paul Hurtubise ◽  
Gabriel Michael ◽  
Amadeo Pesce ◽  
Victor Pollak
Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
Y Abe ◽  
M Futamura-Masuda ◽  
K Murata ◽  
H Matsuda

2019 ◽  
Vol 1 (4) ◽  
pp. 21-26 ◽  
Author(s):  
O. V. Bobko ◽  
O. V. Tikhomirova ◽  
N. N. Zybina ◽  
O. A. Klitsenko

The objective of the study is to show significance of desynchronosis laboratory markers in risk assessment of metabolic syndrome (MS) development. Materials and Methods. There were examined 98 men, aged 43-88, diagnosed with dyscirculatory encephalopathy showing one and more risk factors for development of cardiovascular diseases. They were divided into 2 groups according to the international guidelines of 2009: with MS (n = 61) and without MS (n = 37). Parameters of fats, glucose metabolism, inflammatory mediators, fat tissue metabolism markers, melatonin metabolite excretion (6-sulfatoxymelatonin) were defined in blood serum and urine. Results. The article presents data on changes in leptin, adiponectin, PAI-1, testosterone production and 6-sulfatoxymela-tonin excretion in patients with MS. There are calculated threshold values of these markers definitely increasing MS risk and logistic regression equation which allows assessing MS risk for an individual patient. Conclusion. Detected disorders of melatonin synthesis diurnal dynamics in patients with MS and interconnection between melatonin production and adiponectin, leptin, PAI-1, testosterone synthesis allow considering these parameters as desynchronosis markers significant for MS development.


2019 ◽  
Vol 98 (1) ◽  
pp. 186-192
Author(s):  
D.Yu. Ovsyannikov ◽  
◽  
L.G. Kuzmenko ◽  
T.I. Nazarova ◽  
M. Haled ◽  
...  

Author(s):  
Weam S Al-Hamadany

Ionizing radiation considered as an immunosuppressive factor upon over dose of exposure. Radiation field workers usually following a periodic checkup to monitor changes in their clinical status. Cell Mediated Immunity (CMI) has an important cytokines that regulate this specific immunological process. This study estimated the Interleukins (IL-2, IL-12 and IL-18) levels in serum samples using ELISA technique. Serum samples were collected from X-ray Technicians (Radiography, Fluoroscopy and Computed Tomography Scan Technicians) working in AL-Muthanna governorate hospitals. A total of (60) technicians and (30) control were involved in this research. Results showed significant decrease in IL-2 levels and increase in IL-18 levels in test groups (technicians) as compared with controls. While, IL-12 levels did not show a difference; all obtained values were within normal range. Overdose of X-ray exposure caused CMI suppression via disturbing the levels of critical cytokines (IL-2 and IL-18) leading to CMI loss regulation.


Sign in / Sign up

Export Citation Format

Share Document