Background Data on Tumor Incidence in Control Animals (Syrian Hamsters)

2015 ◽  
pp. 259-265 ◽  
Author(s):  
F. Homburger
Keyword(s):  
Tumor Incidence ◽  
Syrian Hamsters ◽  
Background Data

Postnatal growth rate and gonadal development in circadian tau mutant hamsters reared in constant dim red light

Reproduction ◽  
2000 ◽  
pp. 327-330 ◽  
Author(s):  
RJ Lucas ◽  
JA Stirland ◽  
YN Mohammad ◽  
AS Loudon
Keyword(s):  
Time Course ◽  
Red Light ◽  
Somatic Growth ◽  
Postnatal Growth ◽  
Gonadal Development ◽  
Testicular Development ◽  
Wild Type ◽  
Similar Time ◽  
Syrian Hamsters ◽  
Body Weights

The role of the circadian clock in the reproductive development of Syrian hamsters (Mesocricetus auratus was examined in wild type and circadian tau mutant hamsters reared from birth to 26 weeks of age under constant dim red light. Testis diameter and body weights were determined at weekly intervals in male hamsters from 4 weeks of age. In both genotypes, testicular development, subsequent regression and recrudescence exhibited a similar time course. The age at which animals displayed reproductive photosensitivity, as exhibited by testicular regression, was unrelated to circadian genotype (mean +/- SEM: 54 +/- 3 days for wild type and 59 +/- 5 days for tau mutants). In contrast, our studies revealed a significant impact of the mutation on somatic growth, such that tau mutants weighed 18% less than wild types at the end of the experiment. Our study reveals that the juvenile onset of reproductive photoperiodism in Syrian hamsters is not timed by the circadian system.

THE IMPORTANCE OF THE RED BOOK OF SOILS FOR MONITORING AND JUSTIFICATION OF CONSERVATION MEASURES

2020 ◽  
Author(s):  
O.S. Bezuglova ◽  
Keyword(s):  
Chemical Properties ◽  
Natural State ◽  
Soil Maps ◽  
Rostov Region ◽  
Conservation Measures ◽  
Background Data ◽  
The Russian Federation ◽  
Physical And Chemical ◽  
And Chemical Properties

Rostov Region belongs to the highly protected natural territories characterized by the continuous plowing. There territories are the only reserves with the soils preserved in their natural state. However, these areas often lack detailed information about the soils quality and composition. Surveying soils on these territories is crucial for determination of their basic physical and chemical properties. The resulted compilation of soil maps could lay a foundation for creating the Red Book of Soils and the formation of a section in the soil-geographical database of the Russian Federation. Subsequently, such information can be used as a background data for the main types of soils in the region. It will be also valuable during monitoring and justification of conservation measures.

INTERLEUKIN 6 AND CRP IN THE PREDICTION THE SEVERITY IN PATIENTS OF ACUTE PANCREATITIS

2015 ◽  
pp. 29-35
Author(s):  
Van Xung Nguyen ◽  
Van Huy Tran
Keyword(s):  
Acute Pancreatitis ◽  
Key Words ◽  
Interleukin 6 ◽  
Accuracy Rate ◽  
Background Data ◽  
Single Marker ◽  
Key Words Interleukin 6

Background: Data about the value of interleukin 6 and CRP in the prediction of severity of acute pancreatitis (AP) is still limited. This study is aimed at assessing the values of interleukin 6 and CRP in the prediction the severity of AP. Patients and methods: 55 patients with AP were enrolled. Interleukin was measured at 2 times: the 1st and the 3rd days. Results: IL-6 level day 1 in severe AP (168.86 ± 70.65 pg/ml) was significantly higher than in mild AP (89.54 ± 28.81 pg/ml) and IL-6 day 3 in severe AP (58.64 ± 20.77 pg/ml) significantly higher than mild AP (29.73 ± 14.88 pg/ml). concerning the prediction of severity of AP, IL-6 in day 1 (with cut-off 113.36 pg/ml) had the sensitivity 81.25% and the specificity 84.64%, PPV 68.4% and NPV 91.7%, accuracy rate 88.8%, AUC 0.888 and respectively in day 3 (with cut-off 41.38 pg/ml were 87.5%; 87.18%; 73.7%; 4.4%; 86.7%; 0.867. The values in prediction of severity were significantly higher when combining IL 6 and CRP in compare with the single marker. Conclusion: Combining Interleukin 6 and CRP may have a good value in the prediction of the severity of AP. Key words: Interleukin 6, CRP, acute pancreatitis, severity.

EFFICACY OF TENOFOVIR IN PATIENTS OF HBV-RELATED CIRRHOSIS

2016 ◽  
pp. 25-29
Author(s):  
Van Huy Tran ◽  
Thi Huyen Thuong Nguyen
Keyword(s):  
Side Effects ◽  
Serum Creatinine ◽  
Key Words ◽  
Tenofovir Disoproxil Fumarate ◽  
Hbv Dna ◽  
Treatment Side Effects ◽  
Background Data ◽  
Key Words Cirrhosis

Background: Data about efficacy of Tenofovir in patients of HBV –related cirrhosis in Vietnam was still limited. This study is aimed at: - evaluating the clinical, biochemical, virological and Child-Pugh score responses 3,6,9 months after Tenofovir therapy; - assessing possible side effects of tenofovir. Patients and methods: 40 patients with HBV-related cirrhosis were enrolled. All has received Tenofovir disoproxil fumarate 300mg/day. Follow-up after 3,6 and 9 months. Results: Anorexia, oedema and ascites were significantly improved after treatment. HBV DNA became undetectable in 92.5%, 94.55 and 100% after 3,6 and 9 months, respectively. Child- Pugh score was improved after treatment (5.94±0.22 after treatment vs 7.47±0.28 before treatment). Side effects were minors (nausea, vomiting). No case of increase in serum creatinine was found. Conclusion: Tenofovir showed effective and safe in patients of HBV-related cirrhosis. Key words: Cirrhosis, tenofovir, HBV. Key words: cirrhosis, tenofovir, HBV

Flaxseed and Vitamin E Exert Synergic Antioxidant Action on Diabetic Nephropathy in Experimental Diabetes

2017 ◽  
Vol 68 (7) ◽  
pp. 1449-1452 ◽  
Author(s):  
Raluca Ecaterina Haliga ◽  
Doina Butcovan ◽  
Teodor Oboroceanu ◽  
Alin Constantin Pinzariu ◽  
Victor Vlad Costan ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Vitamin E ◽  
Intraperitoneal Injection ◽  
Experimental Diabetes ◽  
Histological Evaluation ◽  
Standard Diet ◽  
Antioxidant Action ◽  
Syrian Hamsters

This study investigated the effects of flaxseed and vitamin E on diabetic nephropathy lesions in an experimental-induced model of diabetes in hamsters. Diabetes was induced by intraperitoneal injection of streptozotocin (STZ) in male Golden Syrian hamsters, and diabetic animals were fed either standard diet, or standard diet supplemented with flaxseed (150 g/kg diet), vitamin E (400 mg a-tocopherol/kg diet) or combination of flaxseed and vitamin E in the same dosages, for 20 weeks. Kidney histological evaluation of the diabetic hamsters revealed histological lesions characteristic for diabetic nephropathy, while supplementation of the diet with flaxseed and/or vitamin E improved histological aspects of diabetic nephropathy.

Background Data Measures for Predicting Security Risks: A Construct Approach

1992 ◽  
Author(s):  
Michael D. Mumford ◽  
Theodore L. Gessner ◽  
Jennifer O'Connor ◽  
Mary S. Connelly ◽  
Timothy C. Clifton
Keyword(s):  
Security Risks ◽  
Background Data
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