Central Hemodynamic Changes after Induced Incomplete Muscle Ischemia during Aortic Reconstructive Surgery

2015 ◽  
pp. 161-172
Author(s):  
P. Negl�n ◽  
B. Ekl�f ◽  
D. Thomson
1999 ◽  
Vol 31 (1) ◽  
pp. 9-18 ◽  
Author(s):  
M. Rawlins ◽  
E. Gullichsen ◽  
K. Kuttila ◽  
O. Peltola ◽  
J. Niinikoski

2021 ◽  
Vol 17 (3) ◽  
pp. 32-41
Author(s):  
D. S. Shilin ◽  
K. G. Shapovalov

Aim of the study. To examine the effect of prone positioning on hemodynamics in patients with COVID-19.Materials and methods. The study enrolled 84 patients of both sexes with community-acquired multisegmental viral and bacterial pneumonia associated with COVID-19, who were divided into groups according to the type of respiratory support. The tests were performed using the integrated hardware and software system for noninvasive central hemodynamic assessment by volumetric compression oscillometry.Results. We found that the pulse blood pressure velocity decreased from 281 [242.0; 314.0] to 252 [209; 304] mm Hg/s in patients with severe COVID-19 on oxygen support (p=0.005); volume ejection rate decreased from 251 [200; 294] to 226 [186; 260] ml/s (P=0.03); actual/estimated normalized vascular resistance ratio dropped from 0.549 [0.400; 0.700] to 0.450 [0.300; 0.600] (P=0.002), while the arterial wall compliance increased from 1.37 [1.28; 1.67] to 1.45[1.10; 1.60] ml/mm Hg (P=0.009). Prone positioning of patients on noninvasive lung ventilation associated with a reduction of linear blood flow rate from 40.0 [34.0; 42.0] to 42.5 [42.5; 47.25] cm/s (7=0.04) and arterial wall compliance from 1.4 [1.24; 1.50] to 1.32 [1.14; 1.49] ml/mm Hg (7=0.03). Prone positioning of patients on invasive lung ventilation did not result in significant hemodynamic changes.Conclusion. The greatest hemodynamic changes during prone positioning were found in patients on oxygen respiratory support, whereas the least significant alterations were seen in patients on invasive ventilatory support.


2013 ◽  
Vol 305 (9) ◽  
pp. H1387-H1396 ◽  
Author(s):  
Elisabetta Marongiu ◽  
Massimo Piepoli ◽  
Raffaele Milia ◽  
Luca Angius ◽  
Marco Pinna ◽  
...  

The aim of the present study was to test the contribution of stroke volume (SV) in hemodynamic response to muscle metaboreflex activation in healthy individuals. We hypothesized that an acute decrease in cardiac afterload and preload due to the administration of a vasodilating agent could reduce postexercise muscle ischemia (PEMI)-induced SV response. Ten healthy males (age 33.6 ± 1.3 yr) were enrolled and randomly assigned to the following study protocol: 1) PEMI session, 2) control exercise recovery (CER) session, 3) PEMI after sublingual administration of 5 mg of isosorbide dinitrate (ISDN), and 4) CER after ISDN. Central hemodynamics were evaluated by means of impedance cardiography. The main findings were a blunted SV response during metaboreflex following acute arterial and venous vasodilation, associated with a reduction in cardiac diastolic time and filling, and a decrement of systemic vascular resistance. These hemodynamic changes restrain blood pressure response during metaboreflex activation. Our results indicate that hemodynamic response to metaboreflex activation is a highly integrated phenomenon encompassing complex interplay between heart rate, cardiac performance, preload, and afterload and that impairment of one or more of these parameters leads to altered hemodynamic response to metaboreflex.


2015 ◽  
Vol 20 (3) ◽  
pp. 222-229 ◽  
Author(s):  
Wesley K Lefferts ◽  
Kevin S Heffernan ◽  
Eric M Hultquist ◽  
Patricia C Fehling ◽  
Denise L Smith

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