Hepatic Sinusoidal Cells in Iron Overload

2015 ◽  
pp. 91-102
Author(s):  
T. C. Iancu ◽  
L. Lichterman ◽  
H. B. Neustein
Keyword(s):  
Iron Overload ◽  
Sinusoidal Cells

Sinusoidal Cells in Bone Marrow Take Up BSA-Au Conjugates in the Presence of an Artificial Blood Substitute

1985 ◽  
Vol 43 ◽  
pp. 700-701
Author(s):  
J.S. Geoffroy ◽  
R.P. Becker
Keyword(s):  
Bone Marrow ◽  
Los Angeles ◽  
Iliac Artery ◽  
Blood Substitute ◽  
Sprague Dawley ◽  
Coated Pits ◽  
Sinusoidal Cells ◽  
Artificial Blood ◽  
Left Common Iliac Artery

The pattern of BSA-Au uptake in vivo by endothelial cells of the venous sinuses (sinusoidal cells) of rat bone marrow has been described previously. BSA-Au conjugates are taken up exclusively in coated pits and vesicles, enter and pass through an “endosomal” compartment comprised of smooth-membraned tubules and vacuoles and cup-like bodies, and subsequently reside in multivesicular and dense bodies. The process is very rapid, with BSA-Au reaching secondary lysosmes one minute after presentation. (Figure 1)In further investigations of this process an isolated limb perfusion method using an artificial blood substitute, Oxypherol-ET (O-ET; Alpha Therapeutics, Los Angeles, CA) was developed. Under nembutal anesthesia, male Sprague-Dawley rats were laparotomized. The left common iliac artery and vein were ligated and the right iliac artery was cannulated via the aorta with a small vein catheter. Pump tubing, preprimed with oxygenated 0-ET at 37°C, was connected to the cannula.

HFE genotype and the insulin resistance syndrome among subjects with iron overload

2001 ◽  
Vol 120 (5) ◽  
pp. A565-A565
Author(s):  
J TALWALKAR ◽  
H TORGERSON ◽  
D BRANDHAGEN
Keyword(s):  
Insulin Resistance ◽  
Iron Overload ◽  
Insulin Resistance Syndrome

Abstract #914: Polyglandular Autoimmune Syndrome in a Patient with Sickle Cell Anemia and Iron Overload

2005 ◽  
Vol 11 ◽  
pp. 85
Author(s):  
Allison Elise Kerr ◽  
Wolali Odonkor ◽  
Gail Nunlee-Bland ◽  
Juanita Archer ◽  
Anitha Kolukula ◽  
...  
Keyword(s):  
Iron Overload ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Polyglandular Autoimmune Syndrome ◽  
Autoimmune Syndrome

Iron overload in cutaneous porphyria

1969 ◽  
Vol 124 (2) ◽  
pp. 190-196 ◽  
Author(s):  
G. F. Sauer
Keyword(s):  
Iron Overload

Transferrin Saturation Defines Distinct Subtypes of Dysmetabolic Iron Overload Syndrome

2016 ◽  
Vol 54 (05) ◽  
Author(s):  
A Viveiros ◽  
A Finkenstedt ◽  
B Schäfer ◽  
B Henninger ◽  
W Vogel ◽  
...  
Keyword(s):  
Iron Overload ◽  
Transferrin Saturation
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