13 Estimation of Fetal Lung Maturity by the �Shake Test�

2015 ◽  
pp. 73-74
Keyword(s):  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Shake Test ◽  
Lung Maturity

Prediction of fetal lung maturity by use of the Lumadex-FSI test.

1986 ◽  
Vol 32 (2) ◽  
pp. 361-363 ◽  
Author(s):  
G Lockitch ◽  
B K Wittmann ◽  
B E Snow ◽  
D J Campbell
Keyword(s):  
Foam Stability ◽  
Stability Index ◽  
Fetal Lung ◽  
Hyaline Membrane Disease ◽  
Predictive Values ◽  
Fetal Lung Maturity ◽  
Shake Test ◽  
Hyaline Membrane ◽  
Age Range ◽  
Lung Maturity

Abstract We analyzed amniotic fluid from 91 pregnancies (estimated gestational age range 31 to 41 weeks), using the Lumadex-FSI Fetal Lung Maturity test (Beckman Instruments), and also determining phosphatidylglycerol content, the lecithin/sphingomyelin ratio, and foam stability index by the "shake test," and compared results with newborn outcome. Five of 64 babies born within 72 h of testing developed hyaline membrane disease. Except for the lecithin/sphingomyelin ratio, the predictive value of a negative test was 100% but that of a positive test was less than 50%. Use of all four tests did not offer diagnostic advantage over the use of Lumadex-FSI alone. For the laboratory that infrequently assesses fetal lung maturity, we believe the sealed cassette format of the Lumadex-FSI will permit better quality assurance than the shake test. The Lumadex-FSI test is intended to provide a graded estimate of positive risk for hyaline membrane disease, but more data from different centers and patient populations are needed to establish reliable predictive values.

Evaluation of the Amniostat-FLM assay for assessment of fetal lung maturity.

1984 ◽  
Vol 30 (7) ◽  
pp. 1233-1237 ◽  
Author(s):  
G Lockitch ◽  
B K Wittmann ◽  
S M Mura ◽  
L C Hawkley
Keyword(s):  
Thin Layer ◽  
Amniotic Fluid ◽  
Screening Method ◽  
Fetal Lung ◽  
Hyaline Membrane Disease ◽  
Rapid Screening ◽  
Fetal Lung Maturity ◽  
Shake Test ◽  
Hyaline Membrane ◽  
Lung Maturity

Abstract Results of the "Amniostat-FLM" assay, a rapid semiquantitative test for phosphatidylglycerol, were compared with determinations of the lecithin/sphingomyelin (L/S) ratio, with phosphatidylglycerol measured by two-dimensional thin-layer chromatography, and with results of the "shake test" for 94 specimens of amniotic fluid. Correlation between results with the Amniostat and the other tests was excellent. All four tests are very accurate when predicting lung maturity. The predictive value of a negative test, i.e., that hyaline membrane disease would not occur, was between 92 and 100%. However, the accuracy of predicted lung immaturity is poor. For all four tests, predictions of lung immaturity were incorrect in more than 50% of the cases. Of the 49 infants born within 72 h of testing, none developed hyaline membrane disease when phosphatidylglycerol was detectable by either method or when the shake test indicated fetal lung maturity, but three infants with L/S ratio greater than 2/1 did develop the disease. The Amniostat provides a rapid screening method for detecting phosphatidylglycerol in amniotic fluid, which could well replace the thin-layer chromatographic method for measuring phosphatidylglycerol in the panel of diagnostic tests for fetal lung maturity.

scholarly journals Determination of fetal lung maturity by L/S ratio, “shake test” and phosphatidylglycerol in amniotic fluid.

1979 ◽  
Vol 7 (2) ◽  
pp. 78-84 ◽  
Author(s):  
R. Bustos ◽  
G. Giussi ◽  
J. Vinacur ◽  
P. Duhagón ◽  
R. Magri ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Shake Test ◽  
Lung Maturity

A comparison of the shake test, optical density, L/S ratio (planimetric and stechiometric) and PG for the assessment of fetal lung maturity

1996 ◽  
Vol 24 (4) ◽  
pp. 355-362 ◽  
Author(s):  
Maurizio M. Anceschi ◽  
Juan J. Piazze Garnica ◽  
Vittorio Unfer ◽  
Maria R. Di Benedetto ◽  
Ermelando V. Cosmi
Keyword(s):  
Optical Density ◽  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Shake Test ◽  
Lung Maturity

Improved thin-layer chromatography of disaturated phosphatidylcholine in amniotic fluid.

1981 ◽  
Vol 27 (2) ◽  
pp. 239-242 ◽  
Author(s):  
M Y Tsai ◽  
M Cain ◽  
M W Josephson
Keyword(s):  
Respiratory Distress ◽  
Thin Layer ◽  
Amniotic Fluid ◽  
Thin Layer Chromatography ◽  
Fetal Lung ◽  
Dipalmitoyl Phosphatidylcholine ◽  
Fetal Lung Maturity ◽  
Coefficients Of Variation ◽  
Layer Chromatography ◽  
Lung Maturity

Abstract We describe an indirect test of fetal lung maturity: the quantitation of disaturated phosphatidylcholine in amniotic fluid. The lipids in samples of amniotic fluid from 172 patients were reacted with osmium tetroxide, and disaturated phosphatidylcholine was then isolated by thin-layer chromatography. Interfering substances were retained by a pre-adsorbent layer. The charred disaturated phosphatidylcholine, quantitated by densitometry, was compared to standard dipalmitoyl phosphatidylcholine. Both within-run and between-run coefficients of variation were about 10%. Blood and meconium do not interfere. Six infants developed respiratory distress when disaturated phosphatidylcholine concentrations of amniotic fluid drawn within 72 h of delivery were less than 5.5 mg/L. A concurrently determined lecithin/sphingomyelin ratio falsely predicted lung maturity in one of these. In seven other samples for which lecithin/sphingomyelin ratios suggested lung immaturity but disaturated phosphatidyl-choline predicted maturity, none of the infants developed respiratory distress. In normal pregnancies, measurement of disaturated phosphatidylcholine in amniotic fluid appears to be a better predictor of fetal lung maturity than is measurement of the lecithin/sphingomyelin ratio. Further studies are needed to determine if this analysis is a better predictor in diabetic pregnancies.

58: Elective delivery with known fetal lung maturity prior to 39 wks is still associated with increased neonatal morbidity

2011 ◽  
Vol 204 (1) ◽  
pp. S33-S34 ◽  
Author(s):  
Yu Ming Victor Fang ◽  
Peter Guirguis ◽  
Adam Borgida ◽  
Deborah Feldman ◽  
Charles Ingardia ◽  
...  
Keyword(s):  
Neonatal Morbidity ◽  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Elective Delivery ◽  
Lung Maturity

725: PPROM: outcomes of delivery at 32-336/7 weeks after confirmed fetal lung maturity (FLM) versus expectant management until 34 weeks

2014 ◽  
Vol 210 (1) ◽  
pp. S355-S356
Author(s):  
Akila Subramaniam ◽  
Suzanne Cliver ◽  
Stephanie Smeltzer ◽  
Alan Tita ◽  
Luisa Wetta
Keyword(s):  
Expectant Management ◽  
Fetal Lung ◽  
Fetal Lung Maturity ◽  
Lung Maturity
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