Role of Diet, Alcohol and Tobacco in Oesophageal Cancer, as Illustrated by Two Contrasting High-Incidence Areas in the North of Iran and West of France

2015 ◽  
pp. 101-110 ◽  
Author(s):  
A. J. Tuyns ◽  
G. P�quignot ◽  
D. M. Jensen
Keyword(s):  
Oesophageal Cancer ◽  
The North ◽  
High Incidence ◽  
North Of Iran

scholarly journals Role of Aminoglycoside-Modifying Enzymes (AMEs) in Resistance to Aminoglycosides among Clinical Isolates of Pseudomonas aeruginosa in the North of Iran

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Leila Ahmadian ◽  
Zahra Norouzi Bazgir ◽  
Mohammad Ahanjan ◽  
Reza Valadan ◽  
Hamid Reza Goli
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Multidrug Resistant ◽  
Clinical Isolates ◽  
Resistance Pattern ◽  
Dilution Method ◽  
The North ◽  
Agar Diffusion Test ◽  
North Of Iran ◽  
Encoding Genes

In recent years, the prevalence of resistance to aminoglycosides among clinical isolates of Pseudomonas aeruginosa is increasing. The aim of this study was to investigate the role of aminoglycoside-modifying enzymes (AMEs) in resistance to aminoglycosides in clinical isolates of P. aeruginosa. The clinical isolates were collected from different hospitals. Disk agar diffusion test was used to determine the antimicrobial resistance pattern of the clinical isolates, and the minimum inhibitory concentration of aminoglycosides was detected by microbroth dilution method. The PCR was performed for discovery of aminoglycoside-modifying enzyme-encoding genes. Among 100 screened isolates, 43 (43%) isolates were resistant to at least one tested aminoglycosides. However, 13 (13%) isolates were resistant to all tested aminoglycosides and 37 isolates were detected as multidrug resistant (MDR). The resistance rates of P. aeruginosa isolates against tested antibiotics were as follows: ciprofloxacin (41%), piperacillin-tazobactam (12%), cefepime (32%), piperacillin (26%), and imipenem (31%). However, according to the MIC method, 13%, 32%, 33%, and 37% of the isolates were resistant to amikacin, gentamicin, tobramycin, and netilmicin, respectively. The PCR results showed that AAC(6 ′ )-Ib was the most commonly (26/43, 60.4%) identified AME-encoding gene followed by AAC(6 ′ )-IIa (41.86%), APH(3 ′ )-IIb (34.8%), ANT(3 ″ )-Ia (18.6), ANT(2 ″ )-Ia (13.95%), and APH(3 ″ )-Ib (2.32%). However, APH(3 ′ )-Ib was not found in any of the studied isolates. The high prevalence of AME-encoding genes among aminoglycoside-resistant P. aeruginosa isolates in this area indicated the important role of AMEs in resistance to these antibiotics similar to most studies worldwide. Due to the transmission possibility of these genes between the Gram-negative bacteria, we need to control the prescription of aminoglycosides in hospitals.

scholarly journals Morphine does no promote esophageal carcinogenesis in rats exposed to diethylnitrosamine

2008 ◽  
Vol 45 (1) ◽  
pp. 87-92 ◽  
Author(s):  
Carlos Frota Dillenburg ◽  
Cleber Dario Pinto Kruel ◽  
Carlos Thadeu Cerski ◽  
Maria Isabel Edelweiss ◽  
Tiago Luís Dedavid e Silva ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Hepatic Metabolism ◽  
The North ◽  
Experimental Cancer ◽  
High Incidence ◽  
First Pass ◽  
North Of Iran ◽  
Hepatic Neoplasia ◽  
Esophageal Carcinogenesis ◽  
Different Doses

BACKGROUND: The high incidence of esophageal cancer in the north of Iran has been associated to the consumption of opium and exposure to nitrosamines. Diethylnitrosamine has an established potential of producing experimental cancer in the esophagus and liver. AIM: To evaluate by histopathology the effect of oral administration of morphine and diethylnitrosamine during 23 weeks on the hepatic and esophageal carcinogenesis on 176 rats. METHODS: We divided the rats into the following groups: Morph: morphine; Den: diethylnitrosamine; Den+morph: Den and morphine in the same solution; Den/morph: Den and morphine in different solutions and days. RESULTS: Morphine did not promote neoplasias. The highest neoplastic incidents were found: a) in the esophagus, Den in relation to Den/morph and Den+morph (71.1%, 55.8%, and 50.0%); b) in the liver, Den and Den/morph in relation to Den+morph (73.8%, 81.4%, and 40.9%); c) higher incident of hepatic neoplasia than esophageal in Den/morph (81.4% and 55.8%). Different doses of diethylnitrosamine were ingested among the groups Den, Den/morph, and Den+morph, respectively 2.9, 2.8, and 2.3 mg/kg/day. CONCLUSIONS: These results show that the morphine did not promote esophageal carcinogenesis and may have stimulated the hepatic metabolism of the first pass of the carcinogen.

The role of genetic and environmental factors in the development of inhibitors in patients with hemophilia A in the north of Iran

2020 ◽  
Vol 45 (4) ◽  
pp. 197
Author(s):  
Azam Rashidbaghan ◽  
Nargesbeigom Mirbehbahani ◽  
Ayyoob Khosravi ◽  
Sedigheh Livani ◽  
Azam Jahazi ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Hemophilia A ◽  
The North ◽  
North Of Iran ◽  
Genetic And Environmental Factors

The Inherited Past of the Broch: On Antiquarian Discourse and Contemporary Archaeology

2002 ◽  
Vol 24 (1) ◽  
pp. 1-20 ◽  
Author(s):  
ANDREW BAINES
Keyword(s):  
Material Culture ◽  
19Th Century ◽  
Academic Language ◽  
Contemporary Archaeology ◽  
The North

In reading archaeological texts, we expect to be engaged in a characteristically archaeological discourse, with a specific and recognisable structure and vocabulary. In evaluating the published work of 19th Century antiquarians, we will inevitably look for points of contact between their academic language and our own; success or failure in the identification of such points of contact may prompt us to recognise a nascent archaeology in some writings, while dismissing others as naïve or absurd. With this point in mind, this paper discusses the written and material legacies of three 19th Century antiquarians in the north of Scotland who worked on a particular monument type, the broch. The paper explores the degree to which each has been admitted as an influence on the development of the broch as a type. It then proceeds to compare this established typology with the author's experiences, in the field, of the sites it describes. In doing so, the paper addresses wider issues concerning the role of earlier forms of archaeological discourse in the development of present day archaeological classifications of, and of the problems of reconciling such classifications with our experiences of material culture.

Training of Village Teachers in Vilna Educational District in the 1860s and 1870s

2020 ◽  
Vol 58 ◽  
pp. 181-192
Author(s):  
Anna A. Komzolova
Keyword(s):  
Educational Reform ◽  
Rural Teachers ◽  
Cultural Brokers ◽  
The North ◽  
Central Russia ◽  
Russian Intelligentsia ◽  
Trained Teachers ◽  
The Village ◽  
North Western

One of the results of the educational reform of the 1860s was the formation of the regular personnel of village teachers. In Vilna educational district the goal was not to invite teachers from central Russia, but to train them on the spot by establishing special seminaries. Trained teachers were supposed to perform the role of «cultural brokers» – the intermediaries between local peasants and the outside world, between the culture of Russian intelligentsia and the culture of the Belarusian people. The article examines how officials and teachers of Vilna educational district saw the role of rural teachers as «cultural brokers» in the context of the linguistic and cultural diversity of the North-Western Provinces. According to them, the graduates of the pedagogical seminaries had to remain within the peasant estate and to keep in touch with their folk «roots». The special «mission» of the village teachers was in promoting the ideas of «Russian elements» and historical proximity to Russia among Belarusian peasants.

Peranan Ombudsman Republik Indonesia Perwakilan Sumatera Utara Dalam Pengawasan Pelayanan Dinas Kependudukan dan Catatan Sipil Kota Medan

2019 ◽  
Vol 1 (1) ◽  
pp. 1-12
Author(s):  
Putri Ananda Sari ◽  
Abdul Kadir ◽  
Beby Mashito Batu Bara
Keyword(s):  
Service Provider ◽  
Qualitative Approach ◽  
First Report ◽  
The North ◽  
Supervision Process ◽  
The Republic ◽  
North Sumatra

This study aims to determine the role of the Ombudsman of the Republic of Indonesia in North Sumatra Representative in the Supervision of Population and Civil Registry Service in Medan City. This study uses a qualitative approach with descriptive methods describing information about the data obtained from the field in the form of written and oral data from the parties studied. Data is collected based on interviews and documentation. The results of this study indicate that the role of the Ombudsman of the Republic of Indonesia in North Sumatra was carried out in the form of external supervision. External supervision is supervision carried out by the Ombudsman of the Republic of Indonesia Representative of North Sumatra to the Medan Population and Civil Registry Service. Actions taken in the supervision process are incoming reports, follow-up of the first report and follow-up of the report. Based on the research that has been carried out, it has been concluded that the role of the Ombudsman of the Republic of Indonesia in the North Sumatra Representative in supervising the service provider of the Population and Civil Registry services is carried out in the form of external supervision. In supervising the handling of public reports of alleged poor service in the area of population administration, it has been effective, with several efforts to handle reports such as: (1) Clarification; (2) Investigation; (3) Recommendations; (4) Monitoring.

Gender Indeterminacy in Translation: the Case of R. L. Stine’s Give Yourself Goosebumps Gamebooks via Portuguese Translation

2018 ◽  
pp. 329-345
Author(s):  
Ana Brígida Paiva
Keyword(s):  
North American ◽  
Grammatical Gender ◽  
Second Person ◽  
The North ◽  
Person Perspective ◽  
Gender Neutral ◽  
Literary Systems ◽  
Second Person Perspective ◽  
Neutral Language

As works of fction, gamebooks offer narrative-bound choices – the reader generally takes on the role of a character inserted in the narrative itself, with gamebooks consequently tending towards being a story told in the second-person perspective. In pursuance of this aim, they can, in some cases, adopt gender-neutral language as regards grammatical gender, which in turn poses a translation challenge when rendering the texts into Portuguese, a language strongly marked by grammatical gender. Stemming from an analysis of a number of gamebooks in R. L. Stine’s popular Give Yourself Goosebumps series, this article seeks to understand how gender indeterminacy (when present) is kept in translation, while examining the strategies used to this effect by Portuguese translators – and particularly how ideas of implied readership come into play in the dialogue between the North-American and Portuguese literary systems.

Colchicum autumnale (Colchicaceae) w okolicach Krakowa – dawne i obecne rozmieszczenie

2019 ◽  
pp. 15-27
Author(s):  
Magdalena Zarzyka-Ryszka
Keyword(s):  
Adjacent Area ◽  
Colchicum Autumnale ◽  
The Past ◽  
The North ◽  
North Eastern ◽  
New Localities ◽  
Present Distribution ◽  
The 19Th Century ◽  
North Eastern Part

The paper describes the past and present distribution of Colchicum autumnale in the vicinity of Cracow, highlights the role of Stanisław Dembosz (who published the first locality of C. autumnale near Igołomia in 1841). Gives information about the occurrence of C. autumnale in Krzeszowice in the 19th century (reported by Bronisław Gustawicz), presents new localities noted in 2012–2014 in meadows in the north-eastern part of the Puszcza Niepołomicka forest and adjacent area (between the Vistula and Raba rivers), and gives a locality found in Cracow in 2005 (no longer extant).

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