Indications and Contraindications of Isovolemic Hemodilution in Clinical Angiology1

2015 ◽  
pp. 149-156
Author(s):  
H. Rieger
Keyword(s):  
Isovolemic Hemodilution

Right and left ventricular O2 uptake during hemodilution and beta-adrenergic stimulation

1993 ◽  
Vol 265 (5) ◽  
pp. H1769-H1777 ◽  
Author(s):  
G. J. Crystal ◽  
S. J. Kim ◽  
M. R. Salem
Keyword(s):  
Blood Flow ◽  
Blood Cells ◽  
Left Ventricular ◽  
Adrenergic Stimulation ◽  
O2 Uptake ◽  
Isovolemic Hemodilution ◽  
Content Difference ◽  
O2 Extraction ◽  
In Series ◽  
O2 Delivery

Myocardial O2 uptake (MVO2) and related variables were compared in right and left ventricles (RV and LV, respectively) during isovolemic hemodilution (HD) alone and combined with isoproterenol (Iso) infusion in 13 isoflurane-anesthetized open-chest dogs. Measurements of myocardial blood flow (MBF) obtained with radioactive microspheres were used to calculate MVO2. Lactate extraction (Lacext) was determined. The study consisted of two experimental series: 1) graded HD (dextran) to hematocrit (Hct) of 10% and 2) Iso (0.1 microgram.kg-1.min-1 iv) during moderate HD (Hct = 18 +/- 1%). In series 1, arteriovenous O2 content difference in both ventricles decreased in parallel with reduced arterial O2 content caused by HD, i.e., percent O2 extraction was constant; MVO2 was maintained by proportional increases in MBF. In series 2, Iso during moderate HD raised MVO2 (RV, +156%; LV, +80%). Higher MVO2 was satisfied by combination of increased MBF and O2 extraction in RV and by increased MBF alone in LV. Lacext remained consistent with adequate myocardial O2 delivery throughout study. Conclusions were that 1) both RV and LV tolerated extreme HD (Hct = 10%) because blood flow reserves were sufficient to fully compensate for reduced arterial O2 content; 2) significant cardiac reserve was evident during HD, which could be recruited Iso; and 3) because increase in MVO2 in RV caused by Iso in presence of HD was partially satisfied by increased O2 extraction, the absence of augmented O2 extraction during HD alone was not due to impaired release of O2 from diluted red blood cells.(ABSTRACT TRUNCATED AT 250 WORDS)

Cardiovascular and Coronary Physiology of Acute Isovolemic Hemodilution

1994 ◽  
Vol 78 (5) ◽  
pp. 1000???1021 ◽  
Author(s):  
Donat R. Spahn ◽  
Bruce J. Leone ◽  
J. G. Reves ◽  
Thomas Pasch
Keyword(s):  
Isovolemic Hemodilution ◽  
Coronary Physiology

DECREASED SPLANCHNIC DO2 AND VO2, AND GASTRIC MUCOSAL ACIDOSIS AFTER SEVERE ISOVOLEMIC HEMODILUTION.

Shock ◽  
2003 ◽  
Vol 19 (Supplement) ◽  
pp. 4
Author(s):  
D Perin ◽  
Poli LF de Figueiredo ◽  
R J Cruz ◽  
E Silva ◽  
M Rocha e Silva
Keyword(s):  
Isovolemic Hemodilution
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