Myocardial Membrane Lipids in Relation to Cardiovascular Disease

2015 ◽  
pp. 130-144 ◽  
Author(s):  
S. Gudbjarnason ◽  
G. �skarsd�ttir ◽  
B. Doell ◽  
J. Hallgr�msson
Keyword(s):  
Cardiovascular Disease ◽  
Membrane Lipids ◽  
Myocardial Membrane

THE ROLE OF MYOCARDIAL MEMBRANE LIPIDS IN THE DEVELOPMENT OF CARDIAC NECROSIS

2009 ◽  
Vol 199 (S587) ◽  
pp. 17-27 ◽  
Author(s):  
Sigmundur Gudbjarnason ◽  
Jonas Hallgrimsson
Keyword(s):  
Membrane Lipids ◽  
Myocardial Membrane ◽  
Cardiac Necrosis

The organization of cell surface membrane domains

1989 ◽  
Vol 47 ◽  
pp. 804-805
Author(s):  
Michael Edidin
Keyword(s):  
Cell Surface ◽  
Membrane Lipids ◽  
Surface Membrane ◽  
Lateral Diffusion ◽  
Cell Types ◽  
Membrane Domains ◽  
Membrane Biology ◽  
Morphological Polarity ◽  
Discrete Domains ◽  
Membrane Components

Cell surface membranes are based on a fluid lipid bilayer and models of the membranes' organization have emphasised the possibilities for lateral motion of membrane lipids and proteins within the bilayer. Two recent trends in cell and membrane biology make us consider ways in which membrane organization works against its inherent fluidity, localizing both lipids and proteins into discrete domains. There is evidence for such domains, even in cells without obvious morphological polarity and organization [Table 1]. Cells that are morphologically polarised, for example epithelial cells, raise the issue of membrane domains in an accute form.The technique of fluorescence photobleaching and recovery, FPR, was developed to measure lateral diffusion of membrane components. It has also proven to be a powerful tool for the analysis of constraints to lateral mobility. FPR resolves several sorts of membrane domains, all on the micrometer scale, in several different cell types.

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