Sperm Transport from the Vagina to the Fallopian Tubes in Women

2015 ◽  
pp. 74-82
Author(s):  
Diane S. F. Settlage ◽  
Masanobu Motoshima ◽  
Donald Tredway
1967 ◽  
Vol 18 (5) ◽  
pp. 755 ◽  
Author(s):  
RJ Lightfoot ◽  
KP Croker ◽  
HG Neil

Sixteen ewes were drawn from each of two ewe flocks, one of which had grazed on oestrogenic pastures for annual periods over the previous 5 years ("clover" treatment) while the other grazed on green oats ("oats" treatment). Fertility of ewes on the clover treatment had decreased progressively, whereas in those on the oats treatment it had remained high. Oestrous ewes were allocated alternately to receive either two or eight services then killed 24 hr post coitus and the numbers of sperm in the cervix, uterus, and fallopian tubes determined. There was no difference in ovarian activity between the two groups; however, highly significant differences were found in the numbers of sperm recovered from the cervix, uterus, and fallopian tubes. Average sperm numbers per fallopian tube were 17,160 and 350 for ewes on the oats and clover treatments respectively. In addition to the reduction in sperm numbers, both the percentage of motile sperm flushed from the cervix and the proportion of recovered ova with sperm attached to the zona pellucida were lower in ewes on the clover treatment. The results suggest that primary failure of sperm transport in ewes on the clover treatment occurred when sperm did not enter the cervix in adequate numbers following service. The significance of these observations in relation to possible causal mechanisms is discussed.


Zygote ◽  
1994 ◽  
Vol 2 (4) ◽  
pp. 363-366 ◽  
Author(s):  
R. H. F. Hunter

Successful liberation and apposition of gametes are essential components of fertility. Normal fertilisation depends upon the establishment of a pre-ovulatory sperm gradient in the female tract between the site of semen deposition and the site of fertilisation in the Fallopian tubes. As a consequence, sperm: egg ratios may be close to unity at the time of activation of most secondary oocytes under conditions of spontaneous mating. In the absence of a sufficient sperm gradient, newly ovulated eggs would be confronted by an excess of spermatozoa resulting in polyspermic fertilisation. Penetration of the vitellus by more than one spermatozoon is pathological in mammals (Beatty, 1957; Austin, 1963). Accordingly, systems that act to regulate sperm progression and competence before the time of ovulation assume a particular importance. During the 1950s, 1960s and 1970s, there was much controversy as to the rate of sperm transport into the Fallopian tubes. Because observations failed to focus on those spermatozoa that could fertilise eggs, the controversy was largely sterile. Nor were the disagreements well founded since some experiments employed artificial insemination whilst others used natural mating. These two quite distinct approaches to introducing a sperm suspension into the female tract could not reasonably form the basis of disagreements on the physiological events of cellular progression. More recent studies have been set in perspective by Overstreet (1983), Harper (1988), Yanagimachi (1988), Hunter (1988, 1991, 1995) and Drobnis & Overstreet (1992)After mating at the onset of oestrus, ram and bull spermatozoa require a minimum of 6–8 h to reach the Fallopian tubes in sufficient numbers to promote suc.cessful fertilisation (Hunter et al., 1980; Hunter & Wilmut, 1982). Spermatozoa displaced to the tubes in a small number of minutes are moribund or dead, not.


1973 ◽  
Vol 24 (9) ◽  
pp. 655-661 ◽  
Author(s):  
Diane S. Fordney Settlage ◽  
Masanobu Motoshima ◽  
Donald R. Tredway

1996 ◽  
Vol 5 (1) ◽  
pp. 37-49 ◽  
Author(s):  
Erica A Bakkum ◽  
J Baptist Trimbos ◽  
Trudy CM Trimbos-Kemper

The formation of adhesions is a significant clinical problem. Complications like bowel obstruction and chronic pelvic pain are known to be related to adhesion formation. Besides these complications, adhesions do play an additional role in the gynaecological patient. Interference with the functioning of the fallopian tubes and ovaries disturbs ovum pickup and sperm transport and may compromise the fertility of patients.


Author(s):  
A. Toledo ◽  
G. Stoelk ◽  
M. Yussman ◽  
R.P. Apkarian

Today it is estimated that one of every three women in the U.S. will have problems achieving pregnancy. 20-30% of these women will have some form of oviductal problems as the etiology of their infertility. Chronically damaged oviducts present problems with loss of both ciliary and microvillar epithelial cell surfaces. Estradiol is known to influence cyclic patterns in secretory cell microvilli and tubal ciliogenesis, The purpose of this study was to assess whether estrogen therapy could stimulate ciliogenesis in chronically damaged human fallopian tubes.Tissues from large hydrosalpinges were obtained from six women undergoing tuboplastic repair while in the early proliferative phase of fheir menstrual cycle. In each case the damaged tissue was rinsed in heparinized Ringers-lactate and quartered.


1986 ◽  
Vol 113 (4) ◽  
pp. 570-575 ◽  
Author(s):  
Firyal S. Khan-Dawood

Abstract. Immunoreactive oxytocin is detectable in the corpora lutea of women and cynomolgus monkeys by radioimmunoassay. To localize the presence of oxytocin and neurophysin I in ovarian tissues of subhuman primates, three corpora lutea and ovarian stromal tissues and two Fallopian tubes obtained during the menstrual cycle of the baboon and decidua from two pregnant baboons were examined using highly specific antisera against either oxytocin or neurophysin I and preoxidase-antiperoxidase light microscopy immunohistochemistry. Oxytocin-like as well as neurophysin I-like immunoreactivities were found in some cells of all the corpora lutea only, but could not be demonstrated in ovarian stromal tissues, Fallopian tubes and decidua. Specificity of the immunocytochemical reaction was further confirmed by immunoabsorption of the antiserum with excess oxytocin or neurophysin, after which the immunoreactivities for both oxytocin and neurophysin in the luteal tissue were negative. Similar controls using normal rabbit serum gave no positive staining for either oxytocin or neurophysin. Counterstaining of the positive immunoreactivities for oxytocin and neurophysin I with Mayer's haematoxylin and eosin demonstrated clearly that the oxytocin and neurophysin I appeared as granular material mainly within the cytoplasm of the luteal cells. The localization of immunoreactive oxytocin and neurophysin I in the corpus luteum of the baboon demonstrates directly the presence of these two neurohypophysial peptides within primate luteal cells and suggests their local production.


2019 ◽  
pp. 92-95
Author(s):  
D.G. Sumtsov ◽  
◽  
M.L. Kusyomenska ◽  
G.A. Sumtsov ◽  
◽  
...  

In the literature review the authors present an analysis of the current stateproblem of ovarian cancer and ways of its possible solution. According to clinicalobservations and conducted in recent decades by morphological,immunohistochemical and molecular genetic studies it is fairly proved that theprimary cause of serous ovarian cancer is the pathology of the mucous layer offallopian tube. In the fallopian tube as a result of ciculation of inflammation andcarcinogens elements arises dysplasia of the mucosa with the development of thepreinvasive and initial invasive carcinoma with subsequent damage of the ovariesand pelvic peritoneum. Retrospective studies of a significant number of women’shealth status who had a deligation or removal of fallopian tubes in previous years showed a decrease in the disease incidence of serous ovarian cancer from 30 to 90%. The conclusions about the possibility of preventive measures of ovariancancer by opportunistic salpingectomy at post-productive age are made. In many world countries (Canada, China, France, Italy, Austria) the introduction of such a method of prevention has been started. We believe that in Ukraine there is an urgent need and all possibilities to solve this problem. Key words: ovarian cancer, preventive measures, opportunistic salpingectomy.


Author(s):  
Sonalika Hiremath ◽  
Santhosh Kumar S. ◽  
Sridevi Swamy

Infertility primarily refers to the biological inability of a person to contribute to conception. In women, it may also refer to the state when she is not able to carry a pregnancy to its full term. Female infertility is caused due to structural problems like blocked Fallopian tubes, defect in cervical canal, uterine fibroid or polyps. Hormonal imbalance leading .ovulation problems too can cause infertility. From Ayurvedic perspectives, Shukra Dhatu can get affected by various physical, mental causes and even by serious diseases. Poor quality Shukra Dhatu can cause infertility in males and females.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tsuyoshi Murata ◽  
Yuta Endo ◽  
Shigenori Furukawa ◽  
Atsushi Ono ◽  
Yuichiroh Kiko ◽  
...  

Abstract Background Ovarian abscesses, which occur mostly in sexually active women via recurrent salpingitis, occur rarely in virginal adolescent girls. Here, we present a case of an ovarian abscess in a virginal adolescent girl who was diagnosed and treated by laparoscopy. Case presentation A 13-year-old healthy girl presented with fever lasting for a month without abdominal pain. Computed tomography scan and magnetic resonance imaging indicated a right ovarian abscess. Laparoscopic surgery revealed a right ovarian abscess with intact uterus and fallopian tubes. The abscess was caused by Staphylococcus aureus. The patient recovered completely after excision of the abscess, followed by antibiotic treatment. Conclusions Ovarian abscess may occur in virginal adolescent girls; Staphylococcus aureus, an uncommon species causing ovarian abscess, may cause the infection.


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