Drugs and the Prevention of Thrombosis in Shunts

2015 ◽  
pp. 138-146
Author(s):  
P. Didisheim ◽  
M. Pavlovsky ◽  
I. Kobayashi
Keyword(s):  
Prevention Of Thrombosis

Prevention of thrombosis after hip arthroplasty

1988 ◽  
Vol 59 (2) ◽  
pp. 139-143 ◽  
Author(s):  
Bart Swierstra ◽  
Jeanne Stibbe ◽  
Hubert Schouten
Keyword(s):  
Hip Arthroplasty ◽  
Prevention Of Thrombosis

scholarly journals Oral Squamous Cell Carcinoma Is Associated with a Low Thrombosis Risk Due to Storage Pool Deficiency in Platelets

Biomedicines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 228
Author(s):  
Pierre Haen ◽  
Lydie Crescence ◽  
Diane Mege ◽  
Alexandre Altié ◽  
Christophe Dubois ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Platelet Reactivity ◽  
Biological Features ◽  
Prevention Of Thrombosis ◽  
Paradoxical Situation ◽  
Thrombosis Risk ◽  
Tongue Tumor

Venous thrombo-embolism (VTE) disease is the second most common cause of mortality in cancer patients, and evaluation and prevention of thrombosis risk is essential. VTE-associated risk varies according to the type of tumor disease. Oral cancer is the most frequent type of head and neck cancer, and it represents approximately 2.1% of all cancers worldwide. Most tumors are squamous cell carcinomas and are mainly due to tobacco and alcohol abuse. VTE risk associated with oral squamous cell carcinoma (OSCC) is low. However, many studies have shown that OSCC has the following biological features of cancers associated with a high thrombosis risk: modified thrombosis and fibrinolysis mechanisms; strong expression of procoagulant proteins; secretion of procoagulant microparticles; and production of procoagulant cytokines. Using an original mouse model of tongue squamous cell carcinoma, our study aimed to clarify this paradoxical situation. First, we showed that OSCC tumors have a pro-aggregatory phenotype and a high local thrombosis risk. Second, we found that tongue tumor mice do not have an elevated systemic thrombosis risk (the risk of an “at distance” thrombosis event such as lower extremity deep venous thrombosis or pulmonary embolism) and even show a reduction in risk. Third, we demonstrated that tongue tumor mice show a reduction in platelet reactivity, which explains the low systemic thrombosis risk. Finally, we found that tongue tumor mice present granule pool deficiency, thereby explaining the reduction in platelet reactivity and systemic thrombosis risk.

PREVENTION OF THROMBOSIS

The Lancet ◽  
1964 ◽  
Vol 284 (7364) ◽  
pp. 864
Author(s):  
Sidney Shaw ◽  
GeoffreyD. Pegrum
Keyword(s):  
Prevention Of Thrombosis

scholarly journals Taurolock versus saline 5% on preventing infection and dysfunction of hemodialysis catheters; a randomized, double blind controlled clinical trial

2020 ◽  
Vol 10 (3) ◽  
pp. e25-e25
Author(s):  
Ali Ghorbani ◽  
Fatemeh Hayati ◽  
Mehrdad Dargahi-MalAmir ◽  
Maryam Afkane
Keyword(s):  
Central Venous Catheters ◽  
Controlled Clinical Trial ◽  
Organic Solution ◽  
Central Venous ◽  
Double Blind ◽  
Catheter Related Infection ◽  
Prevention Of Thrombosis ◽  
Catheter Dysfunction ◽  
Significant Difference ◽  
Prevention Of Infections

Introduction: Despite the higher rate of morbidity and mortality, the use of central venous catheters has increased significantly compared to arteriovenous fistula. So far, no ideal organic solution has been identified for the prevention of thrombosis and catheter-related infection in patients undergoing hemodialysis. Objectives: This study aimed to evaluate the efficacy of Taurolock versus saline 5% on the prevention of catheter dysfunction and catheter-related infections. Patients and Methods: Seventy patients with chronic kidney disease, who requiring hemodialysis or those with permanent hemodialysis catheters referring to hemodialysis centers of Ahvaz, were selected and randomly divided into two groups, while 68 patients remained until the end of the study. In the first group, saline 5% was inserted into the lumen of catheter after each hemodialysis, and then catheter was blocked. In the second group, Taurolock solution (TauroLock™ -Hep 500®: Taurolidine; antimicrobial agent), citrate 4% and heparin (UI/mL) were used as antibiotics. Results: No significant difference between the catheter-related infection and positive blood culture in both saline and Taurolock groups was detected (2.94% versus 2.94%; P >0.05). Moreover, the catheter-related dysfunction in the saline 5% group was 5% less than the Taurolock group (2.94% versus 11.76%, P = 0.365). Conclusion: The results showed that saline 5% is at least as effective as a Taurolock solution for prevention of infections and catheter dysfunction. Saline is an effective, inexpensive, safe and readily available in various settings. Therefore, it could be considered as a proper alternative solution for reduction of dialysis-related side effects and costs. Trial Registration: Registration of trial protocol has been approved in Iranian registry of controlled trials (identifier: IRCT20190304042918N1; https://en.irct.ir/trial/38055, ethical code# IR.AJUMS.REC.1397.412).

scholarly journals A systematic review and meta-analysis of elastic stockings for prevention of thrombosis after orthopedic surgery

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Bo Tan ◽  
Chengwei Xiao ◽  
Ming Cheng ◽  
Zongdong Zhu ◽  
Feng Liao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Orthopedic Surgery ◽  
Meta Analysis ◽  
Prevention Of Thrombosis ◽  
Elastic Stockings

scholarly journals Frey. Thrombosis and embolism; their prevention and treatment. (Ther. Gegenwart, 1937, I, 22-23)

1937 ◽  
Vol 33 (10) ◽  
pp. 1287-1287
Author(s):  
B. Ivanov
Keyword(s):  
Old Age ◽  
Indications For Surgery ◽  
Prevention Of Thrombosis ◽  
Prevention And Treatment

Prevention of thrombosis and embolism begins with the establishment of indications for surgery; in old age, only vital interventions should be performed; during menstruation, you should avoid any operations, except for urgent ones.

scholarly journals Nitric Oxide-Producing Cardiovascular Stent Coatings for Prevention of Thrombosis and Restenosis

2020 ◽  
Vol 8 ◽  
Author(s):  
Jingdong Rao ◽  
Ho Pan Bei ◽  
Yuhe Yang ◽  
Yu Liu ◽  
Haodong Lin ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular Stent ◽  
Prevention Of Thrombosis

scholarly journals Causes and Management of Non-cirrhotic Portal Hypertension​

2020 ◽  
Vol 22 (12) ◽  
Author(s):  
Stefania Gioia ◽  
Silvia Nardelli ◽  
Lorenzo Ridola ◽  
Oliviero Riggio
Keyword(s):  
Liver Transplantation ◽  
Portal Hypertension ◽  
Natural History ◽  
Portal Vein ◽  
Liver Failure ◽  
Western World ◽  
Vein Thrombosis ◽  
Prevention Of Thrombosis ◽  
Portal Cavernoma ◽  
History Of

Abstract Purpose of the Review Non-cirrhotic portal hypertension (NCPH) includes a heterogeneous group of conditions. The aim of this paper is to make an overview on the denominations, diagnostical features and management of porto-sinusoidal vascular disease (PSVD) and chronic portal vein thrombosis (PVT) being the main causes of NCPH in the Western world. Recent Findings The management of NCPH consists in the treatment of associated diseases and of portal hypertension (PH). PH due to PSVD or PVT is managed similarly to PH due to cirrhosis. TIPS placement and liver transplantation are considerable options in patients with refractory variceal bleeding/ascites and with progressive liver failure. Anticoagulation is a cornerstone both in the treatment of thrombosis in PSVD and in the prevention of thrombosis recurrence in patients with portal cavernoma. Summary Physicians should be aware of the existence of PSVD and chronic PVT and actively search them in particular settings. To now, the management of portal hypertension-related complications in NCPH is the same of those of cirrhosis. Large cooperative studies on the natural history of NCPH are necessary to better define its management.

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