Regulation of Serum-Derived Chemotactic Activity by the Leucotactic Binary Peptide System

2015 ◽  
pp. 442-463 ◽  
Author(s):  
J. H. Wissler ◽  
E. Sorkin ◽  
Vera J. Stecher
Keyword(s):  
Chemotactic Activity ◽  
Peptide System

Permeability Enhancing and Chemotactic Activities of Lower Molecular Weight Degradation Products of Human Fibrinogen

1981 ◽  
Vol 45 (01) ◽  
pp. 090-094 ◽  
Author(s):  
Katsuo Sueishi ◽  
Shigeru Nanno ◽  
Kenzo Tanaka
Keyword(s):  
Molecular Weight ◽  
Degradation Products ◽  
Electron Microscopic Observation ◽  
Chemotactic Activity ◽  
Lower Molecular Weight ◽  
Electron Microscopic ◽  
Human Fibrinogen ◽  
Rabbit Skin ◽  
Molecular Weights ◽  
Active Fragments

SummaryFibrinogen degradation products were investigated for leukocyte chemotactic activity and for enhancement of vascular permeability. Both activities increased progressively with plasmin digestion of fibrinogen. Active fragments were partially purified from 24 hr-plasmin digests. Molecular weights of the permeability increasing and chemotactic activity fractions were 25,000-15,000 and 25,000 respectively. Both fractions had much higher activities than the fragment X, Y, D or E. Electron microscopic observation of the small blood vessels in rabbit skin correlated increased permeability with the formation of characteristic gaps between adjoining endothelial cells and their contraction.These findings suggest that lower molecular weight degradation products of fibrinogen may be influential in contributing to granulocytic infiltration and enhanced permeability in lesions characterized by deposits of fibrin and/or fibrinogen.

Attenuation of Compensation of Endogenous Cardiac Natriuretic Peptide System in Chronic Heart Failure

Circulation ◽  
1997 ◽  
Vol 96 (2) ◽  
pp. 509-516 ◽  
Author(s):  
Takayoshi Tsutamoto ◽  
Atsuyuki Wada ◽  
Keiko Maeda ◽  
Tomoko Hisanaga ◽  
Yukiharu Maeda ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Natriuretic Peptide ◽  
Peptide System ◽  
Natriuretic Peptide System

scholarly journals Tibolone has anti-inflammatory effects in estrogen-deficient female rats on the natriuretic peptide system and TNF-alpha

2012 ◽  
Vol 179 (1-3) ◽  
pp. 55-60 ◽  
Author(s):  
Ana Raquel Santos de Medeiros ◽  
Aline Zandonadi Lamas ◽  
Izabela Facco Caliman ◽  
Polyana L. Meireles Dalpiaz ◽  
Luciana Barbosa Firmes ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Female Rats ◽  
Tnf Alpha ◽  
Peptide System ◽  
Anti Inflammatory ◽  
Natriuretic Peptide System
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