Synchronization of Human Tissues and its Consequences for Cancer Therapy in ENT

Synthesis and Applications of Hydrogels in Cancer Therapy

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871521409666200120094048 ◽

2020 ◽

Vol 20 (12) ◽

pp. 1431-1446

Author(s):

Anchal Singhal ◽

Niharika Sinha ◽

Pratibha Kumari ◽

Manoushikha Purkayastha

Keyword(s):

Drug Delivery ◽

Tissue Engineering ◽

Cancer Therapy ◽

Mechanical Strength ◽

Biomedical Applications ◽

Three Dimensional ◽

Polymer Chains ◽

Human Tissues ◽

Methods Of Synthesis

: Hydrogels are water-insoluble, hydrophilic, cross-linked, three-dimensional networks of polymer chains having the ability to swell and absorb water but do not dissolve in it, that comprise the major difference between gels and hydrogels. The mechanical strength, physical integrity and solubility are offered by the crosslinks. The different applications of hydrogels can be derived based on the methods of their synthesis, response to different stimuli, and their different kinds. Hydrogels are highly biocompatible and have properties similar to human tissues that make it suitable to be used in various biomedical applications, including drug delivery and tissue engineering. The role of hydrogels in cancer therapy is highly emerging in recent years. In the present review, we highlighted different methods of synthesis of hydrogels and their classification based on different parameters. Distinctive applications of hydrogels in the treatment of cancer are also discussed.

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Microstructural comparison of synthetic bioceramics with natural bioceramics

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100084491 ◽

1991 ◽

Vol 49 ◽

pp. 38-39

Author(s):

Shulin Wen ◽

Jingwei Feng ◽

A. Krajewski ◽

A. Ravaglioli

Keyword(s):

Recent Work ◽

Human Body ◽

Human Tissues ◽

Main Constituent ◽

Laboratory Furnace ◽

Chinese Adult ◽

Human Enamel ◽

Biological Compatibility ◽

Synthetic Hydroxyapatite ◽

Synthetic Work

Hydroxyapatite bioceramics has attracted many material scientists as it is the main constituent of the bone and the teeth in human body. The synthesis of the bioceramics has been performed for years. Nowadays, the synthetic work is not only focused on the hydroapatite but also on the fluorapatite and chlorapatite bioceramics since later materials have also biological compatibility with human tissues; and they may also be very promising for clinic purpose. However, in comparison of the synthetic bioceramics with natural one on microstructure, a great differences were observed according to our previous results. We have investigated these differences further in this work since they are very important to appraise the synthetic bioceramics for their clinic application.The synthetic hydroxyapatite and chlorapatite were prepared according to A. Krajewski and A. Ravaglioli and their recent work. The briquettes from different hydroxyapatite or chlorapatite powders were fired in a laboratory furnace at the temperature of 900-1300°C. The samples of human enamel selected for the comparison with synthetic bioceramics were from Chinese adult teeth.

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Immunoelectron microscopic localization of elastic tissue in archival material using an improved method

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100161539 ◽

1990 ◽

Vol 48 (3) ◽

pp. 794-795

Author(s):

J. C. Fanning ◽

J. F. White ◽

R. Polewski ◽

E. G. Cleary

Keyword(s):

Normal Animal ◽

Animal Tissue ◽

Elastic Tissue ◽

Human Tissues ◽

Improved Method ◽

Tissue Samples ◽

Archival Material ◽

Immuno Electron Microscopy ◽

Arteries And Veins ◽

Biochemical Examination

Elastic tissue is an important component of the walls of arteries and veins, of skin, of the lungs and in lesser amounts, of many other tissues. It is responsible for the rubber-like properties of the arteries and for the normal texture of young skin. It undergoes changes in a number of important diseases such as atherosclerosis and emphysema and on exposure of skin to sunlight.We have recently described methods for the localizationof elastic tissue components in normal animal and human tissues. In the study of developing and diseased tissues it is often not possible to obtain samples which have been optimally prepared for immuno-electron microscopy. Sometimes there is also a need to examine retrospectively samples collected some years previously. We have therefore developed modifications to our published methods to allow examination of human and animal tissue samples obtained at surgery or during post mortem which have subsequently been: 1. stored frozen at -35° or -70°C for biochemical examination; 2.

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Multifunctional metal–organic framework heterostructures for enhanced cancer therapy

Chemical Society Reviews ◽

10.1039/d0cs00178c ◽

2021 ◽

Author(s):

Jintong Liu ◽

Jing Huang ◽

Lei Zhang ◽

Jianping Lei

Keyword(s):

Cancer Therapy ◽

General Principle ◽

Biomedical Applications ◽

Metal Organic Framework ◽

Metal Organic ◽

Functional Modulation ◽

Organic Framework

We review the general principle of the design and functional modulation of nanoscaled MOF heterostructures, and biomedical applications in enhanced therapy.

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