The Joint Center for Radiation Therapy

Author(s):  
S. Hellman
1985 ◽  
Vol 3 (4) ◽  
pp. 490-494 ◽  
Author(s):  
J S Loeffler ◽  
T J Ervin ◽  
P Mauch ◽  
A Skarin ◽  
H J Weinstein ◽  
...  

Primary lymphomas of the CNS are rare tumors accounting for less than 2% of all extranodal non-Hodgkin's lymphomas. The treatment for this disease has been disappointing. Radiation therapy and surgery have produced consistently poor control of this disease, with a median survival of 15 months. We have reviewed ten cases of primary lymphoma of the CNS treated at the Joint Center for Radiation Therapy or Dana-Farber Cancer Institute (Boston) from 1968 to 1981. All patients had biopsy-proven CNS lymphomas without systemic disease at presentation. In our series, control of CNS lymphoma was seen only in patients receiving craniospinal radiation or CNS-penetrating chemotherapy.


1981 ◽  
Vol 7 (11) ◽  
pp. 1549-1552 ◽  
Author(s):  
Jay R. Harris ◽  
Leslie Botnick ◽  
William D. Bloomer ◽  
John T. Chaffey ◽  
Samuel Hellman

2007 ◽  
Vol 68 (1) ◽  
pp. 183-186 ◽  
Author(s):  
Tracy A. Balboni ◽  
Ming-Hui Chen ◽  
Jay R. Harris ◽  
Abram Recht ◽  
Mary Ann Stevenson ◽  
...  

1989 ◽  
Vol 14 (3) ◽  
pp. 203-208 ◽  
Author(s):  
Gilbert S. Lederman ◽  
Terence S. Herman ◽  
Maxine Jochelson ◽  
Barbara J. Silver ◽  
John T. Chaffey ◽  
...  

Cancer ◽  
1988 ◽  
Vol 61 (10) ◽  
pp. 1992-1998 ◽  
Author(s):  
Edward N. Hughes ◽  
John Shillito ◽  
Stephen E. Sallan ◽  
Jay S. Loeffler ◽  
J. Robert Cassady ◽  
...  

1984 ◽  
Vol 2 (7) ◽  
pp. 719-732 ◽  
Author(s):  
E M Rosen ◽  
J R Cassady ◽  
C N Frantz ◽  
C Kretschmar ◽  
R Levey ◽  
...  

The treatment results for 118 patients with neuroblastoma seen at the Joint Center for Radiation Therapy/Dana-Farber Cancer Institute/Children's Hospital from 1970 to 1980 were analyzed. Patients were treated with a combination of surgery, radiation therapy, and chemotherapy depending on stage and age. Disease-free survival was excellent in all patient groups except those over one year of age with stage IV disease, a group for which currently available therapy cures only a small proportion of patients. Patients with stage III disease and older patients with stage II disease did extremely well (survival of 81% and 89%, respectively) and may have benefited from intensive treatment with all three modalities. Survival for infants (under one year) with stage IV neuroblastoma (90%) has clearly improved with intensive combination chemotherapy. With combination approaches and newer, more effective systemic regimens, a real impact on survival appears to have been made in the last decade. Better approaches will be necessary to cure more than an occasional older patient with stage IV disease.


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