Uric Acid Lithiasis Associated with Excessive Purine Production Due to Mutant Phosphoribosylpyrophosphate Synthetase

2015 ◽  
pp. 96-100
Author(s):  
O. Sperling ◽  
S. Persky-Brosh ◽  
P. Boer ◽  
A. de Vries
Keyword(s):  
Uric Acid ◽  
Phosphoribosylpyrophosphate Synthetase

Inherited superactivity of phosphoribosylpyrophosphate synthetase: Association of uric acid overproduction and sensorineural deafness

1988 ◽  
Vol 85 (3) ◽  
pp. 383-390 ◽  
Author(s):  
Michael A. Becker ◽  
Juan G. Puig ◽  
Felicitas A. Mateos ◽  
Manuel L. Jimenez ◽  
Mitchel Kim ◽  
...  
Keyword(s):  
Uric Acid ◽  
Sensorineural Deafness ◽  
Phosphoribosylpyrophosphate Synthetase

Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman

2003 ◽  
Vol 48 (7) ◽  
pp. 2036-2041 ◽  
Author(s):  
Pablo García-Pavía ◽  
Rosa J. Torres ◽  
Manuel Rivero ◽  
Maqbool Ahmed ◽  
Juan García-Puig ◽  
...  
Keyword(s):  
Uric Acid ◽  
Young Woman ◽  
Phosphoribosylpyrophosphate Synthetase

391 Uric acid blood levels are associated with clinical and echocardiographic parameters of chronic heart failure

2003 ◽  
Vol 2 (1) ◽  
pp. 79
Author(s):  
P PAVLIDIS ◽  
J PARISSIS ◽  
S ANTONOPOULOS ◽  
D POLLATOS ◽  
P KIRIAZOPOULOS ◽  
...  
Keyword(s):  
Heart Failure ◽  
Uric Acid ◽  
Chronic Heart Failure ◽  
Blood Levels ◽  
Echocardiographic Parameters

Serum uric acid and obesity in Hawaiians

JAMA ◽  
1966 ◽  
Vol 196 (4) ◽  
pp. 364-365 ◽  
Author(s):  
L. A. Healey
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid

Increased monocyte to HDL cholesterol ratio in vitamin B12 deficiency: is it related to cardiometabolic risk?

2020 ◽  
pp. 1-8
Author(s):  
Sanem Kayhan ◽  
Nazli Gulsoy Kirnap ◽  
Mercan Tastemur
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Uric Acid ◽  
Vitamin B12 ◽  
Cardiometabolic Risk ◽  
Vitamin B12 Deficiency ◽  
Left Ventricular ◽  
Cardiometabolic Risk Factors ◽  
B12 Deficiency ◽  
Deficiency Group

Abstract. Vitamin B12 deficiency may have indirect cardiovascular effects in addition to hematological and neuropsychiatric symptoms. It was shown that the monocyte count-to-high density lipoprotein cholesterol (HDL-C) ratio (MHR) is a novel cardiovascular marker. In this study, the aim was to evaluate whether MHR was high in patients with vitamin B12 deficiency and its relationship with cardiometabolic risk factors. The study included 128 patients diagnosed with vitamin B12 deficiency and 93 healthy controls. Patients with vitamin B12 deficiency had significantly higher systolic blood pressure (SBP), diastolic blood pressure (DBP), MHR, C-reactive protein (CRP) and uric acid levels compared with the controls (median 139 vs 115 mmHg, p < 0.001; 80 vs 70 mmHg, p < 0.001; 14.2 vs 9.5, p < 0.001; 10.2 vs 4 mg/dl p < 0.001; 6.68 vs 4.8 mg/dl, p < 0.001 respectively). The prevalence of left ventricular hypertrophy was higher in vitamin B12 deficiency group (43.8%) than the control group (8.6%) (p < 0.001). In vitamin B12 deficiency group, a positive correlation was detected between MHR and SBP, CRP and uric acid (p < 0.001 r:0.34, p < 0.001 r:0.30, p < 0.001 r:0.5, respectively) and a significant negative correlation was detected between MHR and T-CHOL, LDL, HDL and B12 (p < 0.001 r: −0.39, p < 0.001 r: −0.34, p < 0.001 r: −0.57, p < 0.04 r: −0.17, respectively). MHR was high in vitamin B12 deficiency group, and correlated with the cardiometabolic risk factors in this group, which were SBP, CRP, uric acid and HDL. In conclusion, MRH, which can be easily calculated in clinical practice, can be a useful marker to assess cardiovascular risk in patients with vitamin B12 deficiency.

Renal excretion of uric acid: Alterations during stressful underwater demolition team training.

1971 ◽  
Author(s):  
Leonard M. Zir ◽  
Robert T. Rubin ◽  
Richard H. Rahe ◽  
Ransom J. Arthur
Keyword(s):  
Uric Acid ◽  
Renal Excretion ◽  
Team Training

Serum uric acid, cholesterol, and cortisol levels: Interrelationships in normal men under stress.

1970 ◽  
Author(s):  
Robert T. Rubin ◽  
Richard H. Rahe ◽  
Brian R. Clark ◽  
Ransom J. Arthur
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Cortisol Levels ◽  
Normal Men
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