Clearance as a Quantitative Measure of Liver Function

2015 ◽  
pp. 144-155 ◽  
Author(s):  
K. Winkler ◽  
S. Keiding ◽  
N. Tygstrup
Keyword(s):  
Liver Function ◽  
Quantitative Measure

Model-derived assessment of urea appearance in response to alanine infusion: A quantitative measure of liver function in cirrhosis

1993 ◽  
Vol 8 (6) ◽  
pp. 550-556
Author(s):  
G. P. BIANCHI ◽  
G. MARCHESINI ◽  
R. BOLZANI ◽  
A. FABBRI ◽  
E. SARTI ◽  
...  
Keyword(s):  
Liver Function ◽  
Quantitative Measure

Acetaminophen: Macula densa hypersecretory activity by induced hepatotoxicity

1987 ◽  
Vol 45 ◽  
pp. 934-935
Author(s):  
S.S. Poolsawat ◽  
C.A. Huerta ◽  
S.TY. Lae ◽  
G.A. Miranda
Keyword(s):  
Cell Proliferation ◽  
Liver Function ◽  
Chronic Inflammation ◽  
Foam Cell ◽  
Term Effect ◽  
Short Term ◽  
Drug Induced ◽  
Experimental Induction ◽  
Tissue Alterations ◽  
Toxic Responses

Introduction. Experimental induction of altered histology by chemical toxins is of particular importance if its outcome resembles histopathological phenomena. Hepatotoxic drugs and chemicals are agents that can be converted by the liver into various metabolites which consequently evoke toxic responses. Very often, these drugs are intentionally administered to resolve an illness unrelated to liver function. Because of hepatic detoxification, the resulting metabolites are suggested to be integrated into the macromolecular processes of liver function and cause an array of cellular and tissue alterations, such as increased cytoplasmic lysis, centrilobular and localized necroses, chronic inflammation and “foam cell” proliferation of the hepatic sinusoids (1-4).Most experimentally drug-induced toxicity studies have concentrated primarily on the hepatic response, frequently overlooking other physiological phenomena which are directly related to liver function. Categorically, many studies have been short-term effect investigations which seldom have followed up the complications to other tissues and organs when the liver has failed to function normally.

Oral Glucose Tolerance as a Test of Liver Function

1953 ◽  
Vol 25 (4) ◽  
pp. 548-552 ◽  
Author(s):  
Thomas J. Rankin ◽  
Robert L. Jenson ◽  
Mahlon Delp
Keyword(s):  
Liver Function ◽  
Glucose Tolerance ◽  
Oral Glucose ◽  
Oral Glucose Tolerance

Abnormal liver function and synthetic estrogens

JAMA ◽  
1965 ◽  
Vol 194 (8) ◽  
pp. 933-933
Author(s):  
H. B. Eisenstadt
Keyword(s):  
Liver Function ◽  
Abnormal Liver Function ◽  
Synthetic Estrogens
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