Quantitative EMG Analysis in Myogenic and Neurogenic Muscle Diseases

2015 ◽  
pp. 469-476
Author(s):  
K. Kunze
Keyword(s):  
Muscle Diseases ◽  
Quantitative Emg

Z-line degradation and phagocytosis of sarcomeric fragments in myonecrosis

1983 ◽  
Vol 41 ◽  
pp. 790-791
Author(s):  
Melinda L. Estes ◽  
Samuel M. Chou
Keyword(s):  
Vastus Lateralis ◽  
Inflammatory Myopathy ◽  
Muscle Disease ◽  
White Female ◽  
Inflammatory Cell Infiltrate ◽  
Limb Weakness ◽  
Muscle Diseases ◽  
History Of ◽  
The Right ◽  
Mononuclear Inflammatory Cell

Many muscle diseases show common pathological features although their etiology is different. In primary muscle diseases a characteristic finding is myofiber necrosis. The mechanism of myonecrosis is unknown. Polymyositis is a primary muscle disease characterized by acute and subacute degeneration as well as regeneration of muscle fibers coupled with an inflammatory infiltrate. We present a case of polymyositis with unusual ultrastructural features indicative of the basic pathogenetic process involved in myonecrosis.The patient is a 63-year-old white female with a one history of proximal limb weakness, weight loss and fatigue. Examination revealed mild proximal weakness and diminished deep tendon reflexes. Her creatine kinase was 1800 mU/ml (normal < 140 mU/ml) and electromyography was consistent with an inflammatory myopathy which was verified by light microscopy on biopsy muscle. Ultrastructural study of necrotizing myofiber, from the right vastus lateralis, showed: (1) degradation of the Z-lines with preservation of the adjacent Abands including M-lines and H-bands, (Fig. 1), (2) fracture of the sarcomeres at the I-bands with disappearance of the Z-lines, (Fig. 2), (3) fragmented sarcomeres without I-bands, engulfed by invading phagocytes, (Fig. 3, a & b ), and (4) mononuclear inflammatory cell infiltrate in the endomysium.

Muscle Diseases (Blue Books of Practical Neurology, vol 24)

2000 ◽  
Vol 57 (7) ◽  
pp. 1082-a-1083
Author(s):  
S. T. Iannaccone
Keyword(s):  
Muscle Diseases

Tropomyosin mutations responsible for muscle weakness in inherited skeletal muscle diseases

2008 ◽  
pp. 20-21
Author(s):  
Julien Ochala ◽  
Anders Oldfors ◽  
Lars Larsson
Keyword(s):  
Skeletal Muscle ◽  
Muscle Weakness ◽  
Muscle Diseases

scholarly journals Title: Gene transfer by pyro-drive jet injector is a novel therapeutic approach for muscle diseases

Gene ◽  
2021 ◽  
Vol 788 ◽  
pp. 145664
Author(s):  
Takafumi Nakae ◽  
Masanori Obana ◽  
Takahiro Maeda ◽  
Akari Ikeda ◽  
Hiroshi Miyazaki ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Therapeutic Approach ◽  
Muscle Diseases ◽  
Novel Therapeutic

127. A quantitative EMG analysis of the external urethral sphincter in continent males with prostatic pathology

2013 ◽  
Vol 124 (11) ◽  
pp. e217
Author(s):  
F. Bianchi ◽  
M. Ferrari ◽  
M. Cursi ◽  
A. Salonia ◽  
U. Capitanio ◽  
...  
Keyword(s):  
Urethral Sphincter ◽  
External Urethral Sphincter ◽  
Quantitative Emg

Dact1 is expressed during chicken and mouse skeletal myogenesis and modulated in human muscle diseases

2021 ◽  
pp. 110645
Author(s):  
Renata Erbert Contriciani ◽  
Fernanda Cristina da Veiga ◽  
Mariana Juliani do Amaral ◽  
Bianca Gazieri Castelucci ◽  
Lizandra Maia de Sousa ◽  
...  
Keyword(s):  
Human Muscle ◽  
Skeletal Myogenesis ◽  
Muscle Diseases
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