Maturation of Afferent Conduction Velocity as Studied by Sensory Nerve Potentials and by Cerebral Evoked Potentials1

2015 ◽  
pp. 52-63 ◽  
Author(s):  
J. E. Desmedt ◽  
P. No�l ◽  
J. Debecker ◽  
J. Nam�che
Keyword(s):  
Conduction Velocity ◽  
Sensory Nerve

Electrophysiological and Clinical Improvement in Non-Invasive Treatment of Carpal Tunnel Syndrome

2020 ◽  
Vol 20 ◽  
Author(s):  
Riccardo Marvulli ◽  
Giancarlo Ianieri ◽  
Grazia Devenuto ◽  
Marta Falcicchio ◽  
Giulia A. Gallo ◽  
...  
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Sleep Quality ◽  
Conduction Velocity ◽  
Carpal Tunnel ◽  
Nerve Conduction ◽  
Nerve Conduction Velocity ◽  
Pantothenic Acid ◽  
Sensory Nerve ◽  
Sensory Nerve Conduction Velocity ◽  
Tunnel Syndrome

Background and Objective: Carpal tunnel syndrome (CTS) is the most common form of nerve entrapment. Clinically, various signs and symptoms compare due to overexposure to mechanical vibrations transmitted to the wrist bones and cartilage, resulting in compression of the sensory and motor nerve fibers of median nerve. Early symptoms include nocturnal paresthesia and electromyography reveals reduced sensory nerve conduction velocity. Aim of this study was to evaluate the efficacy of a dietary integrator composed of acetyl-L-carnitine, α-lipoic acid,quercetin, bromelain, pantothenic acid, C and B1 and B2 and B6 and B12 vitamins in patients with early (minimal) carpal tunnel syndrome. Methods: 36 patients (28 female and 8 male) with early CTS characterized by sensory nerve demyelination and inflammation of the transverse carpal ligament. Patients were divided into two groups, group A (18 patients received physical therapy) and group B (18 patients, received physical therapy and an oral integrator). Clinical (sleep quality questionnaire to measure severity of paresthesia) and neurophysiological assessment (Sensory Nerve Conduction Velocity) performed at baseline, and then at 30 and 60 days after treatment. Results: Sleep quality and Sensory Nerve Conduction Velocity data analysis show improvement in both groups at 30 and 60 days, with statistically difference between them in both time of analysis. Conclusions: In the early CTS, with sensory fibers damage, use of dietary integrator, such as Micronil Dol®, composed composed of acetyl-L-carnitine, α-lipoic acid,quercetin, bromelain, pantothenic acid, C and B1 and B2 and B6 and B12 vitamins can be effective in quick recovery of median nerve sensory.

scholarly journals Associations of cells from both innate and adaptive immunity with lower nerve conduction velocity: the Maastricht Study

2021 ◽  
Vol 9 (1) ◽  
pp. e001698
Author(s):  
Haifa Maalmi ◽  
Kristiaan Wouters ◽  
Hans H C M Savelberg ◽  
Jeroen H P M van der Velde ◽  
Jos P H Reulen ◽  
...  
Keyword(s):  
T Cells ◽  
Adaptive Immunity ◽  
Conduction Velocity ◽  
Nerve Conduction ◽  
Nerve Conduction Velocity ◽  
Essential Feature ◽  
Sensory Nerve ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Innate And Adaptive Immunity

IntroductionDistal sensorimotor polyneuropathy (DSPN) is common in people with diabetes but is also found in pre-diabetes. Peripheral nerve myelin damage, which can be assessed by reduced nerve conduction velocity (NCV), is an essential feature of DSPN. Emerging evidence indicates that the development of DSPN may involve the activation of the immune system. However, available studies have mainly investigated circulating immune mediators, whereas the role of immune cells remains unclear. Therefore, we aimed to test whether leukocyte subsets are associated with NCV.Research design and methodsThis cross-sectional study analyzed data from 850 individuals (of whom 252 and 118 had type 2 diabetes and pre-diabetes, respectively) of the Maastricht Study. NCV was measured in the peroneal and tibial motor nerves and the sural sensory nerve and summed to calculate a standardized NCV sum score. Associations between percentages of leukocyte subsets and NCV sum scores were estimated using linear regression models adjusted for demographic, lifestyle, metabolic and clinical covariates.ResultsAfter adjustment for covariates, higher percentages of basophils and CD4+ T cells were associated with lower NCV (p=0.014 and p=0.005, respectively). The percentage of CD8+ T cells was positively associated with NCV (p=0.022). These associations were not modified by glucose metabolism status (all pinteraction >0.05). No associations were found for monocytes, eosinophils, neutrophils, lymphocytes, total T cells, Treg cells and B cells.ConclusionsThe associations of basophils, CD4+ and CD8+ T cells with NCV suggest that cell types from both innate and adaptive immunity may be implicated in the development of DSPN.

Conduction Velocities and Their Temperature Coefficients in Sensory Nerve Fibres of Cockroach Legs

1967 ◽  
Vol 46 (1) ◽  
pp. 63-84
Author(s):  
K. M. CHAPMAN ◽  
J. H. PANKHURST
Keyword(s):  
Conduction Velocity ◽  
Periplaneta Americana ◽  
Sensory Nerve ◽  
Point Of View ◽  
Conduction Delay ◽  
Nerve Fibres ◽  
Impulse Frequency ◽  
Temperature Coefficients ◽  
Conduction Velocities ◽  
Sensory Encoding

1. Conduction velocities of individual afferent nerve fibres from tactile spines and proprioceptive campaniform sensilla have been measured in situ over the temperature range 5-42° C., in leg preparations of the cockroach Periplaneta americana. 2. Conduction velocities at 20° C. (u20) averaged 3.3±1.4 m./sec., ranging from 1.6 to 11.0 m./sec. 3. Temperature coefficients, expressed as Q10 for the interval 20-30° C., averaged 1.7±0.24, ranging from 1.3 to 2.6. 4. The length of the propagated disturbance is about 2-3 mm., and is nearly temperature-independent. 5. Fibre diameters, estimated from conduction velocity, must be about 10 µ. 6. There is no correlation between conduction velocity and distance from the sensillum to the thoracic ganglion. Conduction delays in fibres conducting within one standard deviation of mean u20 range from about 2 to 15 msec., from the most proximal to the most distal tactile spines. 7. The effect of conduction delay on temporal and spatial sensory encoding is probably unimportant from a behavioural point of view. It contributes a factor of the form exp(-sd/u) to the sensory transfer function, and may be appreciable at upper physiological frequencies of impulse frequency modulation.

scholarly journals Normal neurophysiologic parameters of the median nerve among adult healthy Sudanese population

2020 ◽  
Vol 10 (4) ◽  
pp. 136-141
Author(s):  
Mohammed Salah Elmagzoub ◽  
Ahmed Hassan Ahmed ◽  
Hussam M A Hameed
Keyword(s):  
Action Potential ◽  
Median Nerve ◽  
Conduction Velocity ◽  
Nerve Conduction ◽  
Compound Muscle Action Potential ◽  
Motor Nerve ◽  
Sensory Nerve ◽  
Peak Latency ◽  
Muscle Action Potential ◽  
Sensory Nerve Action

Background: Nerve conduction studies (NCSs) help in delineating the extent distribution of neural lesion, and the diagnosis of peripheral nerve disorders. Because normative nerve conduction parameters were not yet established in Sudan EMG laboratories, this study aims towards having our own reference values, as we are using the American and British parameters. This will allow avoiding the discrepancies that might be induced by many factors. Methods: NCSs were performed in 200 Median nerves of 100 adult healthy Sudanese subjects using standardized techniques. Results: The median SNAP (sensory nerve action potential) values were as follows: distal latency, 2.6±3 ms with a range of (2.3-2.9); peak latency, 3.5±0.5 ms (3.0-4.0); amplitude, 47.7±18.0μV (29.7-65.7); conduction velocity, 53.0±7.8 m/s (45.2-60.8). The following values were obtained for the Median nerve CMAP (compound muscle action potential) at wrist stimulation: distal latency, 3.5±0.5 ms with a range of (3.0-4.0); peak latency, 9.4± 1.0 ms (8.4-10.4); duration, 5.9±0.9 ms (5.0-6.8); amplitude, 12.3±2.5 mV (9.8-14.8); area, 43.0±10.4 mVms (32.6-53.4); conduction velocity, 63.6±6.2 m/s (57.4-69.8). The F wave was 28.4±1.8 ms (26.6-30.2). Conclusion: The overall mean sensory and motor nerve conduction parameters for the tested nerve compared favorably with the existing literature with some discrepancies that were justified.

Conduction velocity is inversely related to axonal length in the median sensory nerve

1998 ◽  
Vol 21 (2) ◽  
pp. 262-263
Author(s):  
Peter B.J. Wu ◽  
John Neff ◽  
Wade S. Kingery ◽  
Elaine S. Date
Keyword(s):  
Conduction Velocity ◽  
Sensory Nerve

scholarly journals Vascular and Neural Dysfunctions in Obese Zucker Rats: Effect of AVE7688

2009 ◽  
Vol 2009 ◽  
pp. 1-8 ◽  
Author(s):  
Eric P. Davidson ◽  
Lawrence J. Coppey ◽  
Travis L. Kleinschmidt ◽  
Christine L. Oltman ◽  
Mark A. Yorek
Keyword(s):  
Conduction Velocity ◽  
Nerve Conduction ◽  
Nerve Conduction Velocity ◽  
Sensory Nerve ◽  
Neutral Endopeptidase ◽  
Zucker Rats ◽  
Thermal Stimulus ◽  
Obese Zucker Rats ◽  
Neural Dysfunctions ◽  
Tactile Response

The purpose of this study was to determine whether AVE7688 a drug that inhibits both angiotensin converting enzyme and neutral endopeptidase activity protects vascular and nerve functions in an animal model of metabolic syndrome. Obese Zucker rats at 20 weeks of age were treated for 12 weeks with AVE7688. Vasodilation in epineurial arterioles was measured by videomicroscopy and nerve conduction velocity was measured following electrical stimulation. Treatment with AVE7688 improved vascular relaxation in response to acetylcholine and motor and sensory nerve conduction velocity. In obese Zucker rats superoxide levels and nitrotyrosine staining were elevated in the aorta and treatment corrected both conditions. Obese Zucker rats were hypoalgesic in response to a thermal stimulus and demonstrated signs of impaired tactile response and both conditions were significantly improved with treatment. Even though obese Zucker rats are normoglycemic vascular and neural dysfunctions develop with age and can be improved by treatment with AVE7688.

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