Spiral Ganglion Virus-Like Particles of Guinea Pigs

2015 ◽  
pp. 178-190
Author(s):  
J. L. Craft ◽  
D. A. Hilding ◽  
P. N. Bhatt ◽  
A. M. Jonas
Keyword(s):  
Guinea Pigs ◽  
Spiral Ganglion ◽  
Virus Like Particles

scholarly journals Effects of delayed treatment with combined GDNF and continuous electrical stimulation on spiral ganglion cell survival in deafened guinea pigs

2009 ◽  
Vol 87 (6) ◽  
pp. 1389-1399 ◽  
Author(s):  
Verena Scheper ◽  
Gerrit Paasche ◽  
Josef M. Miller ◽  
Athanasia Warnecke ◽  
Nurdanat Berkingali ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Ganglion Cell ◽  
Cell Survival ◽  
Guinea Pigs ◽  
Spiral Ganglion ◽  
Delayed Treatment ◽  
Spiral Ganglion Cell

Virus Particles in the Cochlear Spiral Ganglion of Guinea Pigs

1982 ◽  
Vol 94 (1-6) ◽  
pp. 233-239 ◽  
Author(s):  
E. Löhle ◽  
G. S. Kistler ◽  
U. N. Riede ◽  
W. Merck
Keyword(s):  
Guinea Pigs ◽  
Spiral Ganglion ◽  
Virus Particles ◽  
Cochlear Spiral Ganglion

scholarly journals Auditory responses evoked by optical stimulation on the optogenetic-infected cochlear neurons in the guinea pigs

2020 ◽  
Author(s):  
Chen Liu ◽  
Shu Fang ◽  
Da-xiong Ding ◽  
Han-dai Qin ◽  
Shuo-long Yuan ◽  
...  
Keyword(s):  
Cochlear Implants ◽  
Guinea Pigs ◽  
Spiral Ganglion ◽  
Acoustic Stimulation ◽  
Electrophysiological Recording ◽  
Gene Encoding ◽  
Auditory Responses ◽  
Sensorineural Hearing Impairment ◽  
Cochlear Neurons ◽  
Ganglion Neurons

AbstractCochlear implants (CIs) are by far the optimal option to partially restore hearing for the patients of sensorineural hearing impairment (HI) by electrically stimulating spiral ganglion neurons (SGNs). However, wide current spread from each electrode constitute an interface which restricts precision and quality of the electrical CIs. Recently, optogenetic stimulation of the cochlea has been proved as a more optimized approach via adeno-associated virus (AAV) carrying the gene encoding the light-sensitive channelrhodopsin-2. Here, we focus on summarizing recent work on stable and accurate ChR2 expression and compare the electrophysiological recording of optogenetic and acoustic stimulation in adult guinea pigs. Light stimulation generated auditory responses that was similar to that of acoustic stimulation. Moreover, normal hearing adult guinea pigs responded with a rise in amplitudes with increasing light intensity. In conclusion, optogenetic cochlear stimulation achieved good spectral selectivity of artificial sound encoding in a new adult rodent model, suggesting that the capabilities of optogenetics might be applied to improve cochlear implants in the future.

The Peripheral Processes of Spiral Ganglion Cells After Intracochlear Application of Brain-Derived Neurotrophic Factor in Deafened Guinea Pigs

2013 ◽  
Vol 34 (3) ◽  
pp. 570-578 ◽  
Author(s):  
Laurien Waaijer ◽  
Sjaak F. L. Klis ◽  
Dyan Ramekers ◽  
Martinus H. W. Van Deurzen ◽  
Ferry G. J. Hendriksen ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Guinea Pigs ◽  
Ganglion Cells ◽  
Spiral Ganglion ◽  
Brain Derived Neurotrophic Factor

Chronic electrical stimulation does not prevent spiral ganglion cell degeneration in deafened guinea pigs

2010 ◽  
Vol 269 (1-2) ◽  
pp. 169-179 ◽  
Author(s):  
Martijn J.H. Agterberg ◽  
Huib Versnel ◽  
John C.M.J. de Groot ◽  
Marloes van den Broek ◽  
Sjaak F.L. Klis
Keyword(s):  
Electrical Stimulation ◽  
Ganglion Cell ◽  
Guinea Pigs ◽  
Spiral Ganglion ◽  
Cell Degeneration ◽  
Spiral Ganglion Cell ◽  
Chronic Electrical Stimulation

Spiral ganglion cell morphology in guinea pigs after deafening and neurotrophic treatment

2013 ◽  
Vol 298 ◽  
pp. 17-26 ◽  
Author(s):  
Maarten C. van Loon ◽  
Dyan Ramekers ◽  
Martijn J.H. Agterberg ◽  
John C.M.J. de Groot ◽  
Wilko Grolman ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Cell Morphology ◽  
Guinea Pigs ◽  
Spiral Ganglion ◽  
Spiral Ganglion Cell

Detection of Virus-Like Particles in Germinal Centers of Normal Guinea Pigs

1969 ◽  
Vol 130 (2) ◽  
pp. 586-590 ◽  
Author(s):  
B. I. Ma ◽  
D. C. Swartzendruber ◽  
W. H. Murphy
Keyword(s):  
Guinea Pigs ◽  
Germinal Centers ◽  
Virus Like Particles
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