Recent Findings on the Mechanism of Action of Sex Steroid Hormones

2015 ◽  
pp. 44-55
Author(s):  
E. -E. Baulieu
Keyword(s):  
Steroid Hormones ◽  
Mechanism Of Action ◽  
Sex Steroid Hormones ◽  
Sex Steroid

Mechanism of Action of the Sex Steroid Hormones

1976 ◽  
Vol 294 (26) ◽  
pp. 1430-1437 ◽  
Author(s):  
Lawrence Chan ◽  
Bert W. O'Malley
Keyword(s):  
Steroid Hormones ◽  
Mechanism Of Action ◽  
Sex Steroid Hormones ◽  
Sex Steroid

Mechanism of Action of the Sex Steroid Hormones

1976 ◽  
Vol 294 (24) ◽  
pp. 1322-1328 ◽  
Author(s):  
Lawrence Chan ◽  
Bert W. O'Malley
Keyword(s):  
Steroid Hormones ◽  
Mechanism Of Action ◽  
Sex Steroid Hormones ◽  
Sex Steroid

Mechanism of Action of the Sex Steroid Hormones

1976 ◽  
Vol 294 (25) ◽  
pp. 1372-1381 ◽  
Author(s):  
Lawrence Chan ◽  
Bert W. O'Malley
Keyword(s):  
Steroid Hormones ◽  
Mechanism Of Action ◽  
Sex Steroid Hormones ◽  
Sex Steroid

scholarly journals Associations between female lung cancer risk and sex steroid hormones: a systematic review and meta-analysis of the worldwide epidemiological evidence on endogenous and exogenous sex steroid hormones

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hui Zeng ◽  
Zhuoyu Yang ◽  
Jiang Li ◽  
Yan Wen ◽  
Zheng Wu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Steroid Hormones ◽  
Lung Cancer Risk ◽  
Meta Analysis ◽  
Sex Steroid Hormones ◽  
Sex Steroid ◽  
Sex Steroid Hormone ◽  
Hormone Exposure ◽  
Female Lung Cancer

Abstract Background Published findings suggest sex differences in lung cancer risk and a potential role for sex steroid hormones. Our aim was to perform a meta-analysis to investigate the effects of sex steroid hormone exposure specifically on the risk of lung cancer in women. Methods The PubMed, MEDLINE, Web of Science, and EMBASE databases were searched. The pooled odds ratios (ORs) and 95% confidence intervals (95% CIs) for female lung cancer risk associated with sex steroid hormones were calculated overall and by study design, publication year, population, and smoking status. Sensitivity analysis, publication bias, and subgroup analysis were performed. Results Forty-eight studies published between 1987 and 2019 were included in the study with a total of 31,592 female lung cancer cases and 1,416,320 subjects without lung cancer. Overall, higher levels of sex steroid hormones, both endogenous (OR: 0.92, 95% CI: 0.87–0.98) and exogenous (OR: 0.86, 95% CI: 0.80–0.93), significantly decreased the risk of female lung cancer by 10% (OR: 0.90, 95% CI: 0.86–0.95). The risk of lung cancer decreased more significantly with a higher level of sex steroid hormones in non-smoking women (OR: 0.88, 95% CI: 0.78–0.99) than in smoking women (OR: 0.98, 95% CI: 0.77–1.03), especially in Asia women (OR: 0.84, 95% CI: 0.74–0.96). Conclusions Our meta-analysis reveals an association between higher levels of sex steroid hormone exposure and the decreased risk of female lung cancer. Surveillance of sex steroid hormones might be used for identifying populations at high risk for lung cancer, especially among non-smoking women.

Circulating Levels of Sex Steroid Hormones and Gastric Cancer

2021 ◽  
Author(s):  
Yelda A. Leal ◽  
Minkyo Song ◽  
Jovanny Zabaleta ◽  
Gilberto Medina-Escobedo ◽  
Patrick Caron ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Steroid Hormones ◽  
Sex Steroid Hormones ◽  
Sex Steroid ◽  
Circulating Levels
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