Renal Metabolism and Excretion of Ammonia1

Physiology ◽  
2015 ◽  
pp. 123-135 ◽  
Author(s):  
R. F. Pitts ◽  
W. J. Stone
Keyword(s):  
Renal Metabolism

scholarly journals Predicting changes in renal metabolism after compound exposure with a genome-scale metabolic model

2021 ◽  
Vol 412 ◽  
pp. 115390
Author(s):  
Kristopher D. Rawls ◽  
Bonnie V. Dougherty ◽  
Kalyan C. Vinnakota ◽  
Venkat R. Pannala ◽  
Anders Wallqvist ◽  
...  
Keyword(s):  
Metabolic Model ◽  
Renal Metabolism ◽  
A Genome ◽  
Compound Exposure ◽  
Genome Scale

scholarly journals In Vivo Assessment of Metabolic Abnormality in Alport Syndrome Using Hyperpolarized [1-13C] Pyruvate MR Spectroscopic Imaging

Metabolites ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 222
Author(s):  
Nguyen-Trong Nguyen ◽  
Eun-Hui Bae ◽  
Luu-Ngoc Do ◽  
Tien-Anh Nguyen ◽  
Ilwoo Park ◽  
...  
Keyword(s):  
Disease Progression ◽  
Alport Syndrome ◽  
Genetic Disorder ◽  
Lactate Production ◽  
Clinical Importance ◽  
Metabolic Imaging ◽  
Renal Metabolism ◽  
Hyperpolarized 13C ◽  
And Control

Alport Syndrome (AS) is a genetic disorder characterized by impaired kidney function. The development of a noninvasive tool for early diagnosis and monitoring of renal function during disease progression is of clinical importance. Hyperpolarized 13C MRI is an emerging technique that enables non-invasive, real-time measurement of in vivo metabolism. This study aimed to investigate the feasibility of using this technique for assessing changes in renal metabolism in the mouse model of AS. Mice with AS demonstrated a significant reduction in the level of lactate from 4- to 7-week-old, while the levels of lactate were unchanged in the control mice over time. This reduction in lactate production in the AS group accompanied a significant increase of PEPCK expression levels, indicating that the disease progression in AS triggered the gluconeogenic pathway and might have resulted in a decreased lactate pool size and a subsequent reduction in pyruvate-to-lactate conversion. Additional metabolic imaging parameters, including the level of lactate and pyruvate, were found to be different between the AS and control groups. These preliminary results suggest that hyperpolarized 13C MRI might provide a potential noninvasive tool for the characterization of disease progression in AS.

scholarly journals Renal metabolism and urinary excretion of platelet-activating factor in the rat.

1990 ◽  
Vol 265 (32) ◽  
pp. 19414-19419
Author(s):  
M Noris ◽  
N Perico ◽  
D Macconi ◽  
V Nanni ◽  
J Dadan ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Platelet Activating Factor ◽  
Renal Metabolism

Renal Metabolism of theβ-Subunit of Human Choriogonadotropin in the Rat

Endocrinology ◽  
1986 ◽  
Vol 119 (2) ◽  
pp. 924-931 ◽  
Author(s):  
GUY P. LEFORT ◽  
JON M. STOLK ◽  
BRUCE C. NISULA
Keyword(s):  
Renal Metabolism ◽  
Human Choriogonadotropin

Fate of glutamine carbon in renal metabolism

1978 ◽  
Vol 234 (2) ◽  
pp. F123-F129 ◽  
Author(s):  
P. Vinay ◽  
J. P. Mapes ◽  
H. A. Krebs
Keyword(s):  
Renal Metabolism

Effects of Adenine Nucleotides on Renal Metabolism

Nephron ◽  
1969 ◽  
Vol 6 (3) ◽  
pp. 282-296 ◽  
Author(s):  
M.J. Weidemann ◽  
D.A. Hems ◽  
H.A. Krebs
Keyword(s):  
Adenine Nucleotides ◽  
Renal Metabolism

Renal Metabolism

1987 ◽  
pp. 79-132 ◽  
Author(s):  
Charles O. Watlington ◽  
Russell C. Scaduto ◽  
Anton C. Schoolwerth
Keyword(s):  
Renal Metabolism
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