Specific Hyposensitization in Allergic Asthma � Results of a Retrospective Study

2015 ◽  
pp. 285-289
Author(s):  
J. Nikolaus ◽  
R. Wettengel
Keyword(s):  
Retrospective Study ◽  
Allergic Asthma ◽  
Specific Hyposensitization

scholarly journals Classification of non-acute bronchial asthma according to allergy and eosinophil characteristics: a retrospective study

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Yi Jiang ◽  
Ruoli An ◽  
Li Cheng ◽  
Qianru Yue ◽  
Hanwei Zhang ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Lung Function ◽  
Allergic Asthma ◽  
Asthma Management ◽  
Effective Management ◽  
Sputum Cytology ◽  
Eosinophilic Asthma ◽  
Asthma Patients ◽  
Medical University

Abstract Background Investigating the endotypes of the different asthma phenotypes would help disease monitoring, prognosis determination, and improving asthma management standardization. This study aimed to classify asthma into four endotypes according to the allergic and eosinophilic characteristics and explore the phenotypes (clinical characteristics, pulmonary functions, and fractional expired nitric oxide (FeNO)) of each endotype. Methods This retrospective study included non-acute asthma patients treated at the First Hospital of Shanxi Medical University (05/2016–01/2018). The patients were classified into the eosinophilic allergic, eosinophilic non-allergic, non-eosinophilic allergic, and non-eosinophilic non-allergic asthma endotypes. Serum sIgE, lung function, FeNO, and induced sputum cytology were tested and compared among groups. Results Of the 171 included patients, 22 had eosinophilic allergic asthma, 17 had eosinophilic non-allergic asthma, 66 had non-eosinophilic allergic asthma, and 66 had non-eosinophilic non-allergic asthma. Lung function measurements (FEV1%, FEF25%, FEF50%, FEF75%, and FEF25–75%) showed that airway dysfunction was worse in eosinophilic non-allergic asthma than in the other three endotypes (all P < 0.001). In allergic asthma patients, eosinophilic asthma had worse airway dysfunction than non-eosinophilic asthma (all P < 0.05). Similar results were found in non-allergic asthma (all P < 0.01). The FeNO levels in eosinophilic allergic asthma were higher than in eosinophilic non-allergic and non-eosinophilic non-allergic asthma (both P = 0.001). Conclusions FeNO can objectively reflect eosinophilic airway inflammation in asthma. Endotypic classification of asthma patients regarding the allergic and eosinophilic characteristics is conducive to the effective management of patients with asthma.

Effectiveness of omalizumab in Canadian patients with allergic asthma: A retrospective study

2017 ◽  
Author(s):  
Sara Chehab ◽  
William Yang ◽  
Remi Gagnon ◽  
Eliofotisti Psaradellis ◽  
Emmanouil Rampakakis ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Allergic Asthma

scholarly journals Retrospective Study on the Association of Biomarkers With Real-world Outcomes of Omalizumab-treated Patients With Allergic Asthma

2019 ◽  
Vol 41 (10) ◽  
pp. 1956-1971
Author(s):  
Abhishek Kavati ◽  
Maryia Zhdanava ◽  
Benjamin Ortiz ◽  
Jason Lecocq ◽  
Bradd Schiffman ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Allergic Asthma ◽  
Real World

Effectiveness of omalizumab in patients with severe allergic asthma: A retrospective study in China

2021 ◽  
pp. 106522
Author(s):  
Min Zhang ◽  
Meiling Jin ◽  
Xin Zhou ◽  
Jiangtao Lin ◽  
Xiansheng Liu ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Allergic Asthma ◽  
Severe Allergic Asthma

Sequential degranulation of eosinophils induced by antigen or autocoids in allergic humans

1986 ◽  
Vol 44 ◽  
pp. 354-355
Author(s):  
Kate W. Sjoerdsma ◽  
W. James Metzger
Keyword(s):  
Allergic Rhinitis ◽  
Bronchoalveolar Lavage ◽  
Allergic Asthma ◽  
Skin Test ◽  
Positive Skin Test ◽  
Positive Skin ◽  
Human Eosinophil ◽  
Asthmatic Patients ◽  
Allergic Asthmatic ◽  
History Of

Eosinophils are important to the pathogenesis of allergic asthma, and are increased in bronchoalveolar lavage within four hours after bronchoprovocation of allergic asthmatic patients, and remain significantly increased up to 24 hours later. While the components of human eosinophil granules have been recently isolated and purified, the mechanisms of degranulation have yet to be elucidated.We obtained blood from two volunteers who had a history of allergic rhinitis and asthma and a positive skin test (5x5mm wheal) to Alternaria and Ragweed. Eosinophils were obtained using a modification of the method described by Roberts and Gallin.

Postoperative hyperthermia in cats treated with Simbadol or morphine: a retrospective study

2020 ◽  
Vol 47 (6) ◽  
pp. 855.e3
Author(s):  
C. Cannarozzo ◽  
P. Kirch ◽  
L. Campoy ◽  
R. Gleed ◽  
M. Martin-Flores
Keyword(s):  
Retrospective Study

Abstract #1059 Prognostic Factors of Metastatic Thyroid Carcinoma: A Single Center Retrospective Study

2018 ◽  
Vol 24 ◽  
pp. 249
Author(s):  
David Broome ◽  
Gauri Bhuchar ◽  
Ehsan Fayazzadeh ◽  
James Bena ◽  
Christian Nasr
Keyword(s):  
Prognostic Factors ◽  
Retrospective Study ◽  
Thyroid Carcinoma ◽  
Single Center

Abstract #316: Reproductive Life Following Spinal Cord Injury: A Retrospective Study

2006 ◽  
Vol 12 ◽  
pp. 65
Author(s):  
Ghasak Mahmood ◽  
Sylvia J. Shaw ◽  
Yaga Szlachick ◽  
Rod Atkins ◽  
Stefan Bughi
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Retrospective Study ◽  
Cord Injury ◽  
Reproductive Life
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