The Incidence and Aetiology of Low Serum Vitamin B12 After Partial Gastrectomy

2015 ◽  
pp. 512-516
Author(s):  
C. T. Jones ◽  
J. A. Williams ◽  
E. V. Cox ◽  
W. T. Cooke
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Partial Gastrectomy ◽  
Low Serum

scholarly journals Clinical relevance of low serum vitamin B12 concentrations in older people: the Banbury B12 study

2006 ◽  
Vol 35 (4) ◽  
pp. 416-422 ◽  
Author(s):  
Harold Hin ◽  
Robert Clarke ◽  
Paul Sherliker ◽  
Wale Atoyebi ◽  
Kathleen Emmens ◽  
...  
Keyword(s):  
Older People ◽  
Vitamin B12 ◽  
Clinical Relevance ◽  
Serum Vitamin ◽  
Low Serum

High prevalence of low serum vitamin B12 in a multi-ethnic Israeli population

2001 ◽  
Vol 115 (3) ◽  
pp. 707-709 ◽  
Author(s):  
Y. Gielchinsky ◽  
D. Elstein ◽  
R. Green ◽  
J. W. Miller ◽  
Y. Elstein ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Israeli Population ◽  
High Prevalence ◽  
Low Serum

FALSE LOW SERUM VITAMIN B12 VALUES WITH RADIODILUTION ASSAYS USING BLOCKED R-BINDERS

The Lancet ◽  
1983 ◽  
Vol 321 (8333) ◽  
pp. 1104-1105 ◽  
Author(s):  
Jørn Brynskov ◽  
Kjeld Andersen ◽  
Peter Gimsing ◽  
Erik Hippe
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Low Serum

Low Serum Vitamin B12 With Supplement In Pernicious Anemia

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 4722-4722
Author(s):  
Ahmad Jajeh
Keyword(s):  
Vitamin B12 ◽  
Pernicious Anemia ◽  
Serum Vitamin ◽  
White Female ◽  
Iron Supplement ◽  
Cell Counts ◽  
History Of ◽  
Iv Iron ◽  
Oral Supplement ◽  
Low Serum

Pernicious anemia is commonly associated with autoimmune disorders. This abstract will describe three cases with low serum Vitamin B12 even with 2 weeks Vitamin B12 inrtamuscular injection of 1000 micrograms. First patient is thirty nine 39 years old white male with known history of pernicious anemia and Alopecia Totalis with prior history of Methotrexate and cyclosporin treatment. The patient had low serum iron and low iron saturation at initial presentation. He was given IV Iron supplement to saturate iron stores with good result. However, his serum vitamin B12 remain border line low normal below 300 pg/ml ( patient’s level is 210, normal range 180-941 pg/ml), even with every two weeks IM injection for more than six months. Patient was also given oral supplement with no increase in the serum vitamin B12 level. The second patient is sixty eight 68 years old white female with history of colon cancer that underwent resection and history of Hashimoto’s Thyroiditis who was on Thyroid hormonal supplement. Her serum Vitamin B12 level remain borderline low below 300. The third patient is forty 40 years old white female with history of Hypothyroidism and breast cancer that had received adjuvant chemotherapy post Lumpectoy and radiation therapy. This patient was treated with IV intravenous iron supplement for iron deficency with good result. All three patients had blocking antibodies to intrinsic factor and presented with various degree of iron deficency and treated with oral as well as IV iron supplement. Peripheral blood smear were reviewed on all the three patients. Hypersegmentation of neutrophils was seen with normocytic normochromic red cell morphology. One patient had low plateletes count. All patients had white blood cell counts below ten thousands. Two patients showed excess of apoptotic neutrophils. None of the patients had enlarged spleen or adenopathy or evidence of bone marrow hypofunction. All of the above patients improved clinically interm of sense of well being and increased level of energy with vitamin B12 supplement. None of the above patients had abnormal liver or kidney function. All patients had low serum vitamin B12 with one monthly dose IM injection plus oral supplement. All patients had normal LDH level and normal Folic acid level. In conclusion The low serum vitamin B12 levels with adequate supplement that should saturate the liver reserve open an interesting question about the possiblility of Transcobalamine receptor abnormality interm of abnormal function or deficency. Antibodies blocking the receptors or rapid neutrophils turn over is another possibility. Further study needed to solve this delema. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Low serum vitamin B12 in older people: the role of alcohol and thyroid status

2007 ◽  
Vol 36 (2) ◽  
pp. 231-232 ◽  
Author(s):  
A. I. Varghese ◽  
G. I. Varughese
Keyword(s):  
Older People ◽  
Vitamin B12 ◽  
Serum Vitamin ◽  
Thyroid Status ◽  
Low Serum

scholarly journals Association between Food Behaviour of Pregnant Women and Status of Serum Vitamin B12 and Neonatal Outcome – A Cross-Sectional Study

2019 ◽  
Vol 7 (1-2) ◽  
pp. 84-91
Author(s):  
Rowshan Afrooz ◽  
Lipika Ghosh ◽  
Abul Kalam Md Faruq ◽  
Mitheel Ibna Islam
Keyword(s):  
Birth Weight ◽  
Vitamin B12 ◽  
Pregnant Women ◽  
Serum Vitamin ◽  
Cross Sectional Study ◽  
Normal Serum ◽  
Urban Resident ◽  
Sectional Study ◽  
Cross Sectional ◽  
Low Serum

Background & objective: To find the association between serum vitamin B12 and food behavior of the pregnant women and its influence on perinatal outcome. Methods: This cross-sectional study was conducted in the Department of Obstetrics & Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka between June 2012 to July 2013. A total of 102 uncomplicated pregnant women attending at the Obstetrics & Gynaecology Department of BSMMU, Dhaka were the study population. Plasma vitamin B12 was measured by Abbott Axsym System using a Enzyme Immuno Assay Technique with the blood collected in a plain test tube. A serum vitamin B12 level of < 200 pg/mL was considered as low serum vitamin B12 level. The outcome variables were birth weight, small-for-date, neural tube defects and other congenital malformations. Result: The selected pregnant women were housewife (74.5%) from low socioeconomic strata. They were generally urban resident (90.2%) with mean age being 26.4 years. In terms of education 17.6% were primary level, 30.4% SSC level, 31.4% HSC level and 20.6% graduate and higher level educated. Majority (90.2%) was urban resident with average monthly family income being Taka 29460. One-third (33.3%) was overweight and 6.9% obese. Two-thirds (66.7%) were at 37-39 weeks of gestation and nullipara. More than 60% received ANC (antenatal care) aregularly. Over one-third (35.3%) had low serum vitamin B12 (< 200 pg/mL). The food behaviour of the women was found to be associated with vitamin B12 deficiency. The pregnant women with low serum vitamin B12 (< 200 pg/ml) had significantly lower weekly consumption of fishes and eggs which are the rich source of vitamin B12. The weekly fish, eggs and amount of milk consumed by the pregnant women with low serum vitamin B12 were much lower than those consumed by the pregnant women with normal serum vitamin B12. The pregnant women with low serum vitamin B12 were more likely to carry a higher risk of adverse perinatal outcome. The incidences of low-birth weight and small-for-dates were staggeringly higher in women with low serum vitamin B12 (33.3% and 27.8% respectively) compared to those in women with normal serum vitamin B12. Conclusion: The study concluded that pregnant women with low serum vitamin B12 are accustomed to taking low fish and eggs in their daily diet compared to those who have normal serum vitamin B12. The incidence of low birth weight and small-for-date babies are more prevalent in the pregnant women with subclinical deficiency of vitamin B12. Ibrahim Card Med J 2017; 7 (1&2): 84-91

scholarly journals Di Guglielmo's Syndrome with Low Serum Vitamin B12

1963 ◽  
Vol 39 (452) ◽  
pp. 354-356 ◽  
Author(s):  
I. I. J. M. Gibson ◽  
A. Pollock ◽  
L. Stankler
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Low Serum

APPARENT LOW SERUM-VITAMIN-B12 LEVELS ASSOCIATED WITH CHLORPROMAZINE

The Lancet ◽  
1965 ◽  
Vol 286 (7421) ◽  
pp. 1052-1053 ◽  
Author(s):  
Victor Herbert ◽  
ChesterW. Gottlieb ◽  
MarkD. Altschule
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Low Serum
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