Scalp and Forehead Sebum Production in Male Patterned Alopecia1

2015 ◽  
pp. 171-176 ◽  
Author(s):  
H. I. Maibach ◽  
R. Feldmann ◽  
B. Payne ◽  
T. Hutshell
Keyword(s):  
Sebum Production

Molecular Interactions of Different Steroids Contributing to Sebum Production. Review

2018 ◽  
Vol 19 (15) ◽  
pp. 1855-1865 ◽  
Author(s):  
Marisa Cabeza ◽  
Lucero Bautista ◽  
Marisol G. Bravo ◽  
Yvonne Heuze
Keyword(s):  
Molecular Interactions ◽  
Sebum Production

Inhibitory Effects of Chitosan on Sebum Production on Facial Skin

2021 ◽  
Author(s):  
Chinathip Theerawattanawit ◽  
Punnawich Phaiyarin ◽  
Supason Wanichwecharungruang ◽  
Nopadon Noppakun ◽  
Pravit Asawanonda ◽  
...  
Keyword(s):  
Facial Skin ◽  
Inhibitory Effects ◽  
Sebum Production

THE ACTION OF AN ANTI-ANDROGENIC STEROID, 17α-METHYL-B-NORTESTOSTERONE, ON SEBUM SECRETION IN RATS TREATED WITH TESTOSTERONE

1967 ◽  
Vol 38 (2) ◽  
pp. 181-185 ◽  
Author(s):  
F. J. EBLING
Keyword(s):  
Female Rats ◽  
Sebaceous Glands ◽  
Androgenic Steroid ◽  
Sebum Production ◽  
Sebum Secretion ◽  
Do So

SUMMARY An anti-androgenic steroid, 17α-methyl-B-nortestosterone was shown to reduce sebum production in spayed female rats treated simultaneously with testosterone. The sebum production was assessed by measuring the increase in the amount of ether-extractable hair fat over a period of 8 days immediately after washing the rats. Testosterone increased the secretion of sebum mainly by stimulating mitosis in the sebaceous glands and it was shown that the anti-androgenic steroid acted at this site, i.e. by suppressing mitosis. These effects were in contrast to the action of oestradiol which also depressed sebaceous activity, but appeared to do so by interfering with synthesis in the sebaceous cells.

Plasma Testosterone and Estrogen Levels, Urine Testosterone Excretion, and Sebum Production in Males with Acne Vulgaris

1965 ◽  
Vol 25 (12) ◽  
pp. 1660-1664 ◽  
Author(s):  
PETER E. POCHI ◽  
JOHN S. STRAUSS ◽  
GOVIND S. RAO ◽  
INDER R. SARDA ◽  
ENRICO FORCHIELLI ◽  
...  
Keyword(s):  
Acne Vulgaris ◽  
Plasma Testosterone ◽  
Sebum Production

scholarly journals In vitro Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Mark A. T. Blaskovich ◽  
Alysha G. Elliott ◽  
Angela M. Kavanagh ◽  
Soumya Ramu ◽  
Matthew A. Cooper
Keyword(s):  
Antimicrobial Activity ◽  
Resistant Bacteria ◽  
Microbial Infection ◽  
Antibiotic Resistant ◽  
Drug Resistant Bacteria ◽  
Cutibacterium Acnes ◽  
Common Skin ◽  
Sebum Production ◽  
Resistant Strains

Abstract Acne is a common skin affliction that involves excess sebum production and modified lipid composition, duct blockage, colonization by bacteria, and inflammation. Acne drugs target one or more of these steps, with antibiotics commonly used to treat the microbial infection for moderate to severe cases. Whilst a number of other acne therapies are purported to possess antimicrobial activity, this has been poorly documented in many cases. We conducted a comparative analysis of the activity of common topical acne drugs against the principal etiological agent associated with acne: the aerotolerant anaerobic Gram-positive organism Propionibacterium acnes (recently renamed as Cutibacterium acnes). We also assessed their impact on other bacteria that could also be affected by topical treatments, including both antibiotic-sensitive and antibiotic-resistant strains, using broth microdilution assay conditions. Drugs designated specifically as antibiotics had the greatest potency, but lost activity against resistant strains. The non-antibiotic acne agents did possess widespread antimicrobial activity, including against resistant strains, but at substantially higher concentrations. Hence, the antimicrobial activity of non-antibiotic acne agents may provide protection against a background of increased drug-resistant bacteria.

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