Investigative Aspects of Preoperative Irradiation for Advanced Carcinoma of the Larynx and Laryngopharynx

2015 ◽  
pp. 58-71
Author(s):  
J. L. Goldman ◽  
W. H. Friedman
Keyword(s):  
Preoperative Irradiation ◽  
Advanced Carcinoma ◽  
Carcinoma Of The Larynx

scholarly journals Conservative Treatment for Locally Advanced Carcinoma of the Larynx Using Alpha-Crystalline B as a Prognostic Molecular Marker

2021 ◽  
Vol 5 (4) ◽  
pp. 317-322
Author(s):  
Rajab Alzahrani ◽  
◽  
AbdulRahman N Alghamdi ◽  
Ashjan Shami ◽  
Wael H Elsawy ◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Molecular Marker ◽  
Locally Advanced ◽  
Advanced Carcinoma ◽  
Carcinoma Of The Larynx

Early oral feeding following total laryngectomy

2008 ◽  
Vol 123 (3) ◽  
pp. 333-338 ◽  
Author(s):  
J Aswani ◽  
M Thandar ◽  
J Otiti ◽  
J Fagan
Keyword(s):  
Total Laryngectomy ◽  
Cost Effective ◽  
Oral Feeding ◽  
Early Feeding ◽  
Myocutaneous Flaps ◽  
Advanced Carcinoma ◽  
Early Oral Feeding ◽  
Carcinoma Of The Larynx ◽  
A Prospective Study ◽  
Pharyngocutaneous Fistulae

AbstractObjectives:To determine whether, in a developing world context, early oral feeding after laryngectomy is safe, cost-effective and appropriate.Study design:A prospective study of early oral feeding after laryngectomy, compared with retrospective, historical delayed feeding controls.Method:Forty patients underwent total laryngectomy for advanced carcinoma of the larynx with or without hypopharyngeal involvement, not requiring tongue base resection or myocutaneous flaps, and were commenced on oral feeding on the second post-operative day. Thirty-nine laryngectomy patients previously managed in the same unit who had received conventional, delayed oral feeding served as controls.Results:Pharyngocutaneous fistulae developed in 20 per cent of the early feeding patients, compared with 15.4 per cent of the delayed oral feeding controls (p = 0.592). For patients who did not develop fistulae, hospitalisation was shorter in the early oral feeding group (p = 0.007).Conclusion:Early oral feeding for laryngectomy patients is recommended, both in developed and developing countries.

scholarly journals The Incidence of Thyroid Gland Invasion in Patients with Carcinoma of the Larynx who Underwent Total Laryngectomy

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Mawaddah A ◽  
See-Sze S ◽  
Marina MB ◽  
Pua KC ◽  
Abdullah-Sani M
Keyword(s):  
Thyroid Gland ◽  
Total Laryngectomy ◽  
Total Duration ◽  
Study Data ◽  
Adjuvant Radiation ◽  
Advanced Carcinoma ◽  
Carcinoma Of The Larynx ◽  
Case Documentation ◽  
Central Lymph ◽  
Operative Notes

Introduction: Total thyroidectomy or at least hemithyroidectomy is routinely performed alongside total laryngectomy in patients with advanced carcinoma of the larynx. Life-threatening hypocalcaemia and hypothyroidism are common sequelae especially with adjuvant radiation. The study aims to determine the incidence of microscopic thyroid gland invasion and challenge the idea of routine thyroidectomy in advanced carcinoma of the larynx. Materials and Methods: This study was a retrospective observational study. It was done in two tertiary centres in Malaysia between 2003 and 2013 for a total duration of 11 years. A total of 72 patients were included in this study. Data from medical records, operative notes, and histopathological reports were collected and analysed. Results: Three patients (4.2%) had the presence of microscopic thyroid gland invasion. There were no significant associations between microscopic thyroid gland invasion and tumour subsites, histological types of a tumour nor T staging (p>0.05) Conclusion: The incidence of microscopic thyroid gland invasion in advance carcinoma of the larynx is low, disavowing routine thyroidectomy. Limitations: Some factors such as cartilage invasion on CT imaging and central lymph node treatment were not considered due to limitations in case documentation.

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