Effects of Parathyroid Hormone on Glomerular Function

2015 ◽  
pp. 38-45 ◽  
Author(s):  
Iekuni Ichikawa ◽  
Barry M. Brenner
Keyword(s):  
Parathyroid Hormone ◽  
Glomerular Function

Localization of parathyroid hormone/parathyroid hormone-related peptide receptor mRNA in kidney

1996 ◽  
Vol 270 (1) ◽  
pp. F186-F191 ◽  
Author(s):  
K. Lee ◽  
D. Brown ◽  
P. Urena ◽  
N. Ardaillou ◽  
R. Ardaillou ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Rat Kidney ◽  
Glomerular Function ◽  
Receptor Mrna ◽  
Related Peptide ◽  
Collecting Ducts ◽  
The Common ◽  
Pthrp Receptor ◽  
Convoluted Tubules

In kidney, parathyroid hormone (PTH) exerts differential distal effects along the nephron. To define cells expressing receptors for PTH in kidney, we localized PTH/ PTH-related peptide (PTH/PTHrP) receptor mRNA in rat kidney by in situ hybridization. PTH/PTHrP receptor mRNA is localized to glomerular podocytes, convoluted and straight proximal tubules, the cortical portion of thick ascending limbs, and distal convoluted tubules, but was not detected in the thin limb of Henle's loop or in collecting ducts. Northern blot analysis showed that cultured human glomerular podocytes express a unique 4.0-kb PTH/PTHrP receptor transcript but do not express detectable levels of the common approximately 2.4-kb transcript found in whole kidney and in many other tissues. Whereas the tubular localization of PTH/PTHrP receptor mRNA coincides well with previously known sites of PTH action, the intense expression and the unique size of the PTH/PTHrP receptor transcript in glomerular podocytes suggest that PTH and/or PTHrP may play a role(s) in glomerular function.

1361: Acute Changes in Renal Glomerular Function following PCNL in Patients

2007 ◽  
Vol 177 (4S) ◽  
pp. 449-449 ◽  
Author(s):  
Nicole L. Miller ◽  
Rajash K. Handa ◽  
Lynn R. Willis ◽  
Andrew P. Evan ◽  
Ryan F. Paterson ◽  
...  
Keyword(s):  
Glomerular Function ◽  
Acute Changes

Abstract #191 Hallucinations and Paranoia in the Setting of an Intrathyroid Parathyroid Hormone Secreting Nodule

2019 ◽  
Vol 25 ◽  
pp. 56-57
Author(s):  
Robert Gaffey ◽  
Eric Pagan ◽  
Briette Karanfillian ◽  
Sahil Parikh ◽  
Ankit Shah
Keyword(s):  
Parathyroid Hormone

Abstract #615: Hypocalcemia Secondary to Parathyroid Hormone Resistance

2016 ◽  
Vol 22 ◽  
pp. 135
Author(s):  
Mitali Talsania ◽  
Ammara Aziz ◽  
Lauren LaBryer ◽  
Jonea Lim
Keyword(s):  
Parathyroid Hormone ◽  
Hormone Resistance
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