scholarly journals Herpes Viral Origin of the Parsonage-Turner Syndrome: Highlighting of Serological Immune Anti-Herpes Deficiency Cured by Anti-Herpes Therapy

2015 ◽  
Vol 7 (2) ◽  
pp. 110-114
Author(s):  
Jacqueline Le Goaster ◽  
Patrice Bourée ◽  
Charles Ifergan ◽  
Frederic Tangy ◽  
René Olivier ◽  
...  
Keyword(s):  
Turner Syndrome ◽  
Normal Values ◽  
Respiratory Function Tests ◽  
Herpes Viruses ◽  
Chemotherapy Treatment ◽  
Viral Origin ◽  
The Family ◽  
Genetic Deficiency ◽  
First Time

In 2012, a 50 year-old athletic male presented with weakness, pain and unilateral phrenic paralysis, followed by bilateral phrenic paralysis with deep dyspnea. In 2013, the Parsonage-Turner syndrome was diagnosed. When the patient was seen in September 2014 for the first time, he was facing phrenic neuromuscular failure, which led to the hypothesis of neurotropic herpes viruses. A control of the global serological anti-Herpes immunity to analyze his antibody (Ab) levels confirmed herpes immune genetic deficiency. An appropriate herpes chemotherapy treatment was proposed. Immediately, a spectacular recovery of the patient was observed, and after a few weeks, the respiratory function tests showed normal values. The hypothesis of the inductive role of viruses of the herpes family in the Parsonage-Turner syndrome was thus substantiated. The patient's immune deficiency covers the HSV2, HHV3, HHV4, HHV5 and HHV6 Ab levels. This led to the control of herpes in the family lineage: indeed, his daughter presented alterations of her serological herpes Ab levels.

scholarly journals PLOT ELEMENTS AND MOTIVES OF THE NOVEL “CHEVENGUR” IN PLATONOV’S SHORT STORY “POTUDAN RIVER”

2021 ◽  
Vol 26 (1) ◽  
pp. 44-55
Author(s):  
N. Mikhaylovna Malygina ◽  
Keyword(s):  
Short Story ◽  
The Novel ◽  
Love Story ◽  
Planetary Scale ◽  
The Family ◽  
Analytical Review ◽  
Eugene Onegin ◽  
Intertextual Connections ◽  
First Time

The relevance of the article is determined by the researcher of the semantic poetics of Platonov’s story “Potudan River”. We carry out an analytical review of the lifetime criticism and articles of modern researchers about the story, on the basis of which we formulate the purpose of the study, due to the need for a new approach to the interpretation of the work and the identification of the principles of its poetics. The novelty of the article is determined by the identification of the multilayered symbolism of the title of the story, which allows to establish the insufficiency of the conclusions that the content of the “Potudan River” is limited to the family theme. At the level of micropoetics we reveal symbolic details that connect the content of the story with the motive of love for the distant, medical and construction subjects and revealing the planetary scale of the author’s thinking. For the first time, it was established that Platonov’s story “Potudan River” was written based on part of the plot of the novel “Chevengur” – the love story of Alexander Dvanov and Sonya Mandrova. We show that the heroes of the story “Potudan River” Nikita Firsov, Lyuba Kuznetsova and Nikita’s father are doubles of the characters in the novel “Chevengur” by Sasha Dvanov, Sonya Mandrova, and Zakhar Pavlovich. The connection of the image of Lyuba with the archetype of the bride is considered. The paper reveals for the first time the intertextual connections of the story “Potudan River” with the poem “The Bronze Horseman” and the novel in verse “Eugene Onegin” by A. Pushkin, in the texts of which the writer found material for modeling the ordinary fate of the hero. Multi-level connections of the content of the story “Potudan River” with Platonov’s artistic world, which is a complete metatext, are found, which opens up new opportunities for determining the role of the editing technique and the principles of returning to the plots and motives of the works of the 1920s, as well as their transformation in the writer’s work of the 1930s.

Colleters in the vegetative axis of Aechmea blanchetiana (Bromeliaceae): anatomical, ultrastructural and functional aspects

2018 ◽  
Vol 66 (5) ◽  
pp. 379 ◽  
Author(s):  
Igor Ballego-Campos ◽  
Elder Antônio Sousa Paiva
Keyword(s):  
Developmental Stages ◽  
Light And Electron Microscopy ◽  
Secretory Activity ◽  
Functional Roles ◽  
Reproductive Axis ◽  
Functional Aspects ◽  
The Family ◽  
Marginal Cells ◽  
First Time

Colleters are common among eudicotyledons, but few records exist for monocotyledons and other groups of plants. For Bromeliaceae, mucilage secretions that protect the young portions of the plant have been observed only in the reproductive axis, and little is known about the secretory systems behind this or even other kind of secretions in the family. We aimed to describe, for the first time, the occurrence of colleters associated with the vegetative shoot of Aechmea blanchetiana (Baker) L.B.Sm., and elucidate aspects of their structure, ultrastructure and secretory activity. Samples of various portions of the stem axis were prepared according to standard methods for light and electron microscopy. Colleters were found compressed in the axillary portion of leaves and in all leaf developmental stages. Secretory activity, however, was found to be restricted to young and unexpanded leaves. The colleters displayed a flattened hand-like shape formed by a multiseriate stalk and an expanded secretory portion bearing elongated marginal cells. Ultrastructural data confirmed that the secretory role of the colleters is consistent with mucilaginous secretion. The functional roles of the colleters are discussed with regard to environmental context and intrinsic features of the plant, such as the presence of a water-impounding tank.

scholarly journals Fine Structure of Maxillary Palps in Adults of Hermetia illucens (Diptera: Stratiomyidae)

2020 ◽  
Author(s):  
M Pezzi ◽  
C Scapoli ◽  
M Bharti ◽  
M J Faucheux ◽  
M Chicca ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Sexual Dimorphism ◽  
Hermetia Illucens ◽  
The Family ◽  
Sensory Structures ◽  
First Time ◽  
Maxillary Palps ◽  
Scanning Electron

Abstract A relevant species in waste management but also in forensic, medical, and veterinary sciences is the black soldier fly, Hermetia illucens (Linnaeus; Diptera: Stratiomyidae). An ultrastructural study by scanning electron microscopy (SEM) was conducted for the first time on maxillary palps of both sexes, describing in detail the morphology and distribution of sensilla and microtrichia. The maxillary palps, composed of two segments, show sexual dimorphism in length and shape. In both sexes, the first segment is covered only by microtrichia, but the second one is divided into two parts: the proximal one, covered only by microtrichia, and the distal one containing both microtrichia and sensory structures. These structures include two types of sensory pits and one of chaetic sensilla. Due to sexual dimorphism in palp size, females have a higher number of sensory pits. The sexual dimorphism of palps and the presence and role of sensilla in H. illucens was discussed in comparison to other species of the family Stratiomyidae and of other Diptera. This study may represent a base for further investigations on mouthpart structures of this species, involved in key physiological activities, such as feeding, mating and oviposition.

Familial Support for the Elderly in the Past: the Case of London's Working Class in the Early 1930s

1988 ◽  
Vol 8 (3) ◽  
pp. 287-320 ◽  
Author(s):  
Chris Gordon
Keyword(s):  
Working Class ◽  
The Elderly ◽  
Original Data ◽  
Household Composition ◽  
Kinship Networks ◽  
Familial Support ◽  
Starting Point ◽  
The Family ◽  
First Time

ABSTRACTThis paper takes as its starting point the historical debate about the respective roles of family and state in providing, where necessary, for the elderly population. Using the original data cards from the New Survey of London it is possible to consider this in the light of the experience of the working class in London in the early 1930s by analysing data on household composition and income. This is the first time that data on household composition have been assembled for the period after 1881 and before the Census authorities themselves began systematically publishing results from 1951. The picture which emerges, supported by analyses of the income of the elderly, suggests that in this period the role of the family was small, though important no doubt in certain critical situations. It is recognised however that analyses of household structure go only part of the way in illuminating the very complex patterns of assistance which existed. We go on therefore to consider the limitations of this approach and speculate briefly on wider kinship networks, and their potential for assistance.

scholarly journals A Novel Virus Discovered in the Yeast Pichia membranifaciens.

2022 ◽  
Author(s):  
Mark D Lee ◽  
Jack W Creagh ◽  
Lance R Fredericks ◽  
Angela M Crabtree ◽  
Jagsish Suresh Patel ◽  
...  
Keyword(s):  
Tertiary Structure ◽  
Yeast Species ◽  
Molecular Models ◽  
Viral Origin ◽  
Gag Protein ◽  
Pichia Membranifaciens ◽  
The Family ◽  
Dsrna Viruses ◽  
Novel Virus

Mycoviruses are widely distributed across fungi, including yeasts of the Saccharomycotina subphylum. It was recently discovered that the yeast species Pichia membranifaciens contained double stranded RNAs (dsRNAs) that were predicted to be of viral origin. The fully sequenced dsRNA is 4,578 bp in length, with RNA secondary structures similar to the packaging, replication, and frameshift signals of totiviruses of the family Totiviridae. This novel virus has been named Pichia membranifaciens virus L-A (PmV-L-A) and is related to other totiviruses previously described within the Saccharomycotina yeasts. PmV-L-A is part of a monophyletic subgroup within the I-A totiviruses, implying a common ancestry between mycoviruses isolated from the Pichiaceae and Saccharomycetaceae yeasts. Energy minimized AlphaFold2 molecular models of the PmV-L-A Gag protein revealed structural conservation with the previously solved structure of the Saccharomyces cerevisiae virus L-A (ScV-L-A) Gag protein. The predicted tertiary structure of the PmV-L-A Pol and its homologs provide details of the potential mechanism of totivirus RNA-dependent RNA polymerases (RdRps) because of structural similarities to the RdRps of mammalian dsRNA viruses. Insights into the structure, function, and evolution of totiviruses gained from yeasts is important because of their parallels with mammalian viruses and the emerging role of totiviruses in animal disease.

scholarly journals Orchidaceae Juss. in Flora of Chechnya and Their Protection

2019 ◽  
Author(s):  
E L Tasueva ◽  
R S Magomadova ◽  
A S Abdurzakova ◽  
A M Umaeva ◽  
Z I Shakhgirieva ◽  
...  
Keyword(s):  
Vegetation Cover ◽  
Family Members ◽  
Common Species ◽  
Raw Material ◽  
North Caucasus ◽  
The North ◽  
The Family ◽  
Protected Plants ◽  
First Time

For the first time, perennial materials on the Orchidacaeae Juss. family of Chechnya are summarizedб consisting of 15 families and 29 species. The largest genus in the family – Orchis L. is represented by 8 species. The article presents information that all members of the family are protected plants listed in the Red Book of Chechnya, Ingushetia, Dagestan, and the Stavropol Territory. Some species are not included in the list of plants to be protected, including those species that have underground tuberoids and can serve as a source of salep (for instance, Platanthera bifolia, P. chlorantha, Herminium monorchis, Traunsteinera sphaerica, Dactylorhisa incarnata, D. salina, D. urvilleana). In this connection, data on the resources of family members and the potential possibilities of their use as a medicinal raw material are of interest. We have carried out resource studies of the most common species of Orchis tridentata Scop, within the North Caucasus. The obtained data allow us to expand our understanding of the species role of Orchidaceae Juss family. Пoлyчeнныe дaнныe пoзBoляют pacшиpить пpeдcтaBлeниe o poли BидoB ceмeйcтBa Orchidaceae Juss. of the North Caucasus flora in the composition of vegetation cover.

scholarly journals C-/O-GLYCOSYL FLAVONES OF SILENE ITALICA

2019 ◽  
pp. 119-127
Author(s):  
Daniil Nikolayevich Olennikov ◽  
Nina Igorevna Kashchenko ◽  
Nadezhda Konstantinovna Chirikova
Keyword(s):  
High Performance ◽  
Diode Array ◽  
Ionization Mass ◽  
Mass Spectrometry Detection ◽  
Chemical Research ◽  
The Family ◽  
Array Detection ◽  
Genus Silene ◽  
First Time

Chemical research of Silene genus focused on the study of terpene compounds including ecdysteroids and triterpenoids, to the detriment of other classes of compounds. One of these poorly estimated group of substances are flavonoids, namely C-/O-glycosyl flavones, widely represented within the family Caryophyllaceae. Early studies revealed the presence of some C-glycosyl flavones (Zemtsova, Dzhumyrko, 1976; Darmogray, 1977), but a detailed study of the flavonoids was not conducted. Application of high performance chromatography with diode-array detection and electrospray ionization mass-spectrometry detection (HPLC-DAD-ESI-MS) allowed to found 14 flavonoids, which are C-, O- and C,O-glycosyl flavones in the aerial part of S. italica of Georgia origin. Ten components were discovered in S. italica for first time. The identified C-glycosides included monoglycosides as isoorientin, isovitexin, isoscoparin (chrysoeryol-6-C-glucoside) and diglycosides as carlinoside (luteolin-6-C-glucoside-8-C-arabinoside), schaftoside (apigenin-6-C-glucoside-8-C-arabinoside), isoschaftoside (luteolin-6-C-arabinoside-8-C-glucoside) and genkwanin-6-C-glucoside-8-C-arabinoside. Two O-glycosides, cosmosiin and cynaroside, and mixed C,O-glycosides as saponarin, isovitexin-2′′-O-arabinoside, isovitexin-6′′-O-arabinoside and O-hexosides od schaftosude and genkwanin-6-C-glucoside- 8-C-arabinoside were not previously identified in Silene genus. The known literature data (Mamadalieva et al., 2014) and the present data demonstrate the useful role of C-/O-glycosyl flavones in the systematics of the genus Silene.

scholarly journals Urban Scatopsidae (Diptera) of Los Angeles, California, United States

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Dalton de Souza Amorim ◽  
Brian V Brown
Keyword(s):  
United States ◽  
Los Angeles ◽  
Urban Environments ◽  
Insect Biodiversity ◽  
The Family ◽  
Three New Species ◽  
First Time ◽  
Malaise Traps ◽  
Eleven Species

Abstract A total of 2,545 specimens of scatopsids were collected by the BioSCAN project in Los Angeles, California, United States—an urban biodiversity project that worked with citizen scientists managing Malaise traps during 108 wk between September 2013 and October 2016. This is one of the largest collections of minute scavenger flies (Diptera: Scatopsidae) ever reported from a single project. Eleven species were identified: in the Ectaetiinae, Ectaetia betzi sp.nov.; in the Psectrosciarinae, Psectrosciara gonzalezae sp.nov.; in the Scatopsinae–Scatopsini, Scatopse notata (Linnaeus); in the Scatopsinae Colobostematini, Holoplagia guamensis (Johannsen); in the Scatopsinae Swammerdamellini, Aztecatopse huertai sp.nov., Swammerdamella marginata (Cook), Coboldia fuscipes (Meigen), Quateiella quatei (Cook), Abrhexosa grossa (Cook), Abrhexosa ryckmani (Cook), and Cooka melanderi (Cook). The three new species are described and illustrated. Phenology of the species collected is discussed. Of the species collected, Scatopse notata, Holoplagia guamensis and Coboldia fuscipes are widespread, cosmopolitan species. Previous records from southern California suggest that eight other species may exist in the area and were not collected—two of Psectrosciara Enderlein, two of Rhegmoclemina Enderlein, and at least one species of Parascatopse Cook, Apiloscatopse Cook, Colobostema Enderlein, and Akorhexoza Cook. This article documents for the first time the genus Aztecatopse Haenni and Huerta in United States and Holoplagia guamensis in continental United States. Overall, the Los Angeles conurbation has been able to keep over 55% of the expected diversity of the family in the area, and some actions in urban planning could possibly extend considerably this percentage. This study emphasizes the value not only of sampling for insect biodiversity in urban environments but of the role of community (=citizen) science in expanding the breadth of such sampling efforts.

scholarly journals Bcl-2 Family Overexpression and Chemoresistance in Acute Myeloid Leukemia

2018 ◽  
Vol 19 (4) ◽  
pp. 299-309
Author(s):  
Alex José de Melo Silva
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Chemotherapy Treatment ◽  
Apoptosis Pathway ◽  
The Family ◽  
Related Proteins ◽  
The Relationship ◽  
Critical Process ◽  
Acute Myeloid

Abstract The family of Bcl-2 proteins is one of the most responsible for apoptosis pathway, that is a critical process to the maintenance of tissue homeostasis. Bcl-2 is an essential apoptotic regulator belonging to a family of functionally and structurally related proteins known as the Bcl-2 family. Some members of this family act as anti-apoptotic regulators, whereas others act in pro-apoptotic function. The relationship between the pro and anti-apoptotic proteins can regulate whether cells begin the apoptosis or remain its life cycle. Increasing of Bcl-2 expression has been found in some hematologic diseases, such as Acute Myeloid Leukemia (AML) and their effects on responsiveness to anticancer therapy have been recently described. Thus, this review aims to discuss apoptosis and the role of the Bcl-2 family of proteins in chemoresistance when overexpressed in patients committed with Acute Myeloid Leukemia submitted to chemotherapy treatment.

First-Time Leaders and the Role of Organizational Culture in Family Businesses

2021 ◽  
pp. 274-299
Author(s):  
Miodraga Stefanovska - Petkovska ◽  
Marjan I. Bojadjiev ◽  
Ivona Mileva
Keyword(s):  
Organizational Culture ◽  
Leadership Style ◽  
Family Business ◽  
Rapid Evolution ◽  
Family Businesses ◽  
Gender And Age ◽  
The Family ◽  
First Time

The recent decades have witnessed a rapid evolution in the study of family businesses; however, despite their unprecedented importance, the information on family businesses remains fragmented and hard to compare. The uniqueness of family business lies in its structure – it is made up of two connected and interdependent components: family and business. Hence, it is logical to assume that every family business will reflect the family that is behind it. Yet, the characterization of these family values have been the missing component in our understanding of family business. The main aims of the research were (1) to provide understanding of the demographic and leadership characteristics of first time leaders, (2) provide a link between the first time leadership characters and organizational culture (as perceived by the employees), and (3) consequently, their alignment. The research was implemented on nine first time leaders and 837 employees from nine that operate in four industries. The chapter conjectures about the potential role of gender and age in leadership style across industries.

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