scholarly journals Rehabilitation in Patients with Chronic Respiratory Disease Other than Chronic Obstructive Pulmonary Disease: Exercise and Physical Activity Interventions in Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis

Respiration ◽  
2015 ◽  
Vol 89 (3) ◽  
pp. 181-189 ◽  
Author(s):  
Chris Burtin ◽  
Helge Hebestreit
Keyword(s):  
Physical Activity ◽  
Chronic Obstructive Pulmonary Disease ◽  
Cystic Fibrosis ◽  
Pulmonary Disease ◽  
Respiratory Disease ◽  
Chronic Respiratory Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Physical Activity Interventions

The Role of Epithelial-Mesenchymal Transition in Chronic Obstructive Pulmonary Disease

2017 ◽  
Vol 203 (2) ◽  
pp. 99-104 ◽  
Author(s):  
Jo-Maree Courtney ◽  
Patricia L. Spafford
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Respiratory Disease ◽  
Epithelial Mesenchymal Transition ◽  
Chronic Respiratory Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Mesenchymal Transition ◽  
Potential Benefits

Chronic obstructive pulmonary disease (COPD) is a major cause of mortality worldwide, and there is currently no treatment that can halt the progression of the disease. Over the last decade there has been increasing interest in the idea that epithelial-mesenchymal transition (EMT) may be active in COPD. Here we review the evidence for EMT in COPD as well as the current progress being made on understanding the drivers and mechanisms involved. Finally, we discuss the potential benefits that understanding EMT may bring to the field of chronic respiratory disease.

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