scholarly journals Deep Brain Stimulation in Multiple System Atrophy Mimicking Idiopathic Parkinson's Disease

2014 ◽  
Vol 6 (3) ◽  
pp. 232-237 ◽  
Author(s):  
Navamayooran Thavanesan ◽  
Martin Gillies ◽  
Michael Farrell ◽  
Alex L. Green ◽  
Tipu Aziz
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Multiple System Atrophy ◽  
Brain Stimulation ◽  
Idiopathic Parkinson’S Disease ◽  
Idiopathic Parkinson's Disease ◽  
Deep Brain

scholarly journals Deep Brain Stimulation in Sub-Thalamic Nucleus in idiopathic Parkinson’s disease – our initial experience in four cases

2019 ◽  
Vol 9 (1) ◽  
pp. 78-83
Author(s):  
Md Zahid Raihan ◽  
Tipu Zahed Aziz
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Thalamic Nucleus ◽  
Idiopathic Parkinson’S Disease ◽  
Parkinsonian Tremor ◽  
Resting Tremor ◽  
Idiopathic Parkinson's Disease ◽  
Deep Brain

Parkinson’s Disease ( PD ) is a chronic neurodegenerative disease . It’s cardinal features are resting tremor, Rigidity, Akinesia and postural instability. Idiopathic Parkinson’s disease develops mainly due to degeneration of Dopaminergic neurons of Substantia Nigra. The role of Subthalamic Nucleus ( STN ) in the development of Parkinsonian Tremmor and other cardinal features is not completely understood yet. However previous studies in monkeys , administration of MPTP ( 1-methyl-4-phenyl- 1.2.3.6.-tetrahydropyridine ) proved that sub thalamic nucleus has a direct role in the development of Parkinsonian tremor and other features. We used no Micro Electrode Recording (MER) system,only studied clinically that Parkinsonian tremor stopped immediately after placement of electrode and same thing happened after micro stimulation of the sensorymotor region of the sub thalamic nucleus .Then high frequency deep brain stimulation ( DBS ) of these same four patients were assessed six months after surgery which led to a significant reduction of Parkinsonian tremor as well as other cardinal features of PD ( p< 0.001 ) . Both postural and resting tremor disappeared completely in three cases and significantly reduced in one case Bang. J Neurosurgery 2019; 9(1): 78-83

Influence of deep brain stimulation and levodopa on signs and symptoms in Parkinson's disease

2009 ◽  
Vol 36 (S 02) ◽  
Author(s):  
J Gierthmühlen ◽  
P Arning ◽  
G Wasner ◽  
A Binder ◽  
J Herzog ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Signs And Symptoms ◽  
Deep Brain
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