Accuracy of Real-Time Tissue Elastography for the Evaluation of Hepatic Fibrosis in Patients with Chronic Hepatitis B: A Prospective Multicenter Study

2014 ◽  
Vol 32 (6) ◽  
pp. 791-799 ◽  
Author(s):  
Tao Wu ◽  
Jie Ren ◽  
Shu-zhen Cong ◽  
Fan-kun Meng ◽  
Hong Yang ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Real Time ◽  
Chronic Hepatitis B ◽  
Hepatic Fibrosis ◽  
Multicenter Study ◽  
Prospective Multicenter Study ◽  
Tissue Elastography

Non-invasive assessment of liver fibrosis using real-time tissue elastography in patients with chronic hepatitis B

2014 ◽  
Vol 69 (2) ◽  
pp. 194-199 ◽  
Author(s):  
Q. Hu ◽  
S.Y. Zhu ◽  
L.K. Kang ◽  
X.Y. Wang ◽  
H.M. Lun ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Real Time ◽  
Chronic Hepatitis B ◽  
Non Invasive ◽  
Tissue Elastography

Usefulness of New Shear Wave Elastography Technique for Noninvasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B: A Prospective Multicenter Study

2021 ◽  
Author(s):  
Jinfen Wang ◽  
Manli Wu ◽  
Runze Linghu ◽  
Jiandong Chang ◽  
Min Wu ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Multicenter Study ◽  
Acoustic Radiation ◽  
Intraclass Correlation ◽  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Acoustic Radiation Force Impulse ◽  
Prospective Multicenter Study

Abstract Purpose To explore the usefulness of liver stiffness measurements (LSMs) by sound touch elastography (STE) and sound touch quantification (STQ) in chronic hepatitis B (CHB) patients for staging fibrosis. Methods This prospective multicenter study recruited normal volunteers and CHB patients between May 2018 and October 2019. The volunteers underwent LSM by STE and supersonic shear imaging (SSI) or by STQ and acoustic radiation force impulse imaging (ARFI). CHB patients underwent liver biopsy and LSM by both STE/STQ. The areas under the receiver operating characteristic curves (AUCs) for staging fibrosis were calculated. Results Overall, 97 volunteers and 524 CHB patients were finally eligible for the study. The successful STE and STQ measurement rates were both 100 % in volunteers and 99.4 % in CHB patients. The intraclass correlation coefficients (ICCs) for the intra-observer stability of STE and STQ (0.94; 0.90) were similar to those of SSI and ARFI (0.95; 0.87), respectively. STE and STQ showed better accuracy than the aspartate aminotransferase-to-platelet ratio index (APRI) and fibrosis-4 index (FIB-4) (AUC: 0.87 vs 0.86 vs 0.73 vs 0.77) in staging cirrhosis. However, both STE and STQ were not superior to APRI and FIB-4 in staging significant fibrosis (AUC: 0.76 vs 0.73 vs 0.70 vs 0.71, all P-values > 0.05). Conclusion STE and STQ are convenient techniques with a reliable LSM value. They have a similar diagnostic performance and are superior to serum biomarkers in staging cirrhosis in CHB patients.

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