Dermoscopy, Reflectance Confocal Microscopy and Immunohistochemical Analysis in Melanocytic Lesions with Meyerson's Phenomenon

Dermatology ◽  
2014 ◽  
Vol 229 (4) ◽  
pp. 297-305 ◽  
Author(s):  
André Oliveira ◽  
Edith Arzberger ◽  
Cesare Massone ◽  
Regina Fink-Puches ◽  
Iris Zalaudek ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Immunohistochemical Analysis ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions

scholarly journals Correlation of Dermoscopy With In Vivo Reflectance Confocal Microscopy of Streaks in Melanocytic Lesions

2007 ◽  
Vol 143 (6) ◽  
Author(s):  
Alon Scope ◽  
Melissa Gill ◽  
Cristiane Benveuto-Andrade ◽  
Allan C. Halpern ◽  
Salvador Gonzalez ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions

scholarly journals Reflectance Confocal Microscopy and Features of Melanocytic Lesions

2009 ◽  
Vol 145 (10) ◽  
Author(s):  
Giovanni Pellacani ◽  
Marco Vinceti ◽  
Sara Bassoli ◽  
Ralph Braun ◽  
Salvador Gonzalez ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions

Correlation of Dermoscopic Structures of Melanocytic Lesions to Reflectance Confocal Microscopy

2007 ◽  
Vol 143 (2) ◽  
Author(s):  
Alon Scope ◽  
Cristiane Benvenuto-Andrade ◽  
Anna-Liza C. Agero ◽  
Allan C. Halpern ◽  
Salvador Gonzalez ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions

scholarly journals Reflectance Confocal Microscopy: A Promising Tool to Identify Malignancy in Melanocytic Lesions Exhibiting a Dermoscopic Island

2018 ◽  
Vol 109 (6) ◽  
pp. e37-e41
Author(s):  
M. Elosua-González ◽  
R. Gamo-Villegas ◽  
U. Floristán-Muruzábal ◽  
F. Pinedo-Moraleda ◽  
J.L. López-Estebaranz
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Promising Tool ◽  
Melanocytic Lesions

scholarly journals In Vivo Reflectance Confocal Microscopy Enhances Secondary Evaluation of Melanocytic Lesions

2009 ◽  
Vol 129 (1) ◽  
pp. 131-138 ◽  
Author(s):  
Pascale Guitera ◽  
Giovanni Pellacani ◽  
Caterina Longo ◽  
Stefania Seidenari ◽  
Michelle Avramidis ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions

Reflectance confocal microscopy and melanocytic lesions: The road to saving a biopsy.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e21614-e21614
Author(s):  
Ann Mary John ◽  
Attiya Haroon ◽  
Gina Francisco ◽  
Babar K Rao
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
The Road ◽  
Melanocytic Lesions

scholarly journals Lesions Mimicking Melanoma at Dermoscopy Confirmed Basal Cell Carcinoma: Evaluation with Reflectance Confocal Microscopy

Dermatology ◽  
2018 ◽  
Vol 235 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Francesca Peccerillo ◽  
Victor Desmond Mandel ◽  
Francesca Di Tullio ◽  
Silvana Ciardo ◽  
Johanna Chester ◽  
...  
Keyword(s):  
Cluster Analysis ◽  
Confocal Microscopy ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Hierarchical Cluster ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions ◽  
Peripheral Palisading

Background: Atypical basal cell carcinoma (BCC), characterized by equivocal dermoscopic features typical of malignant melanoma (MM), can be difficult to diagnose. Reflectance confocal microscopy (RCM) enables in vivo imaging at nearly histological resolution. Objectives: To evaluate with RCM atypical melanocytic lesions identified in dermoscopy, according to common RCM criteria for the differential diagnosis of BCC, and to identify representative RCM parameters for superficial (sBCCs) and nonsuperficial (nsBCCs) basal cell carcinomas (BCCs). Methods: A retrospective analysis of consecutive patients evaluated with RCM, selecting excised lesions classified at dermoscopy with ≥1 score from the re visited 7-point checklist, mimicking melanoma, registered between 2010 and 2016. Cluster analysis identified BCC subclassifications. Results: Of 178 atypical lesions, 34 lesions were diagnosed as BCCs with RCM. Lesions were confirmed BCCs with histopathology. Dermoscopic features included atypical network (55.9%) and regression structures (35.5%) associated with sBCCs, and an atypical vascular pattern (58.8%) and irregular blotches (58.8%) with nsBCCs. Hierarchical cluster analysis identified 2 clusters: cluster 1 (100% sBCCs) was characterized by the presence of cords connected to the epidermis (90%, p < 0.001), tumor islands located in the epidermis (100%, p < 0.001), smaller vascular diameter (100%, p < 0.001) and solar elastosis (90%, p = 0.017), and cluster 2 (nsBCCs 85%) was defined by the dermic location of tumor islands (87.5%, p < 0.001) with branch-like structures (70.8%, p = 0.007) and surrounding collagen (83.3%, p = 0.012), peripheral palisading (83.3%, p = 0.012) and coiled vascular morphology (79.2%, p < 0.001) with a larger vascular diameter (50%, p < 0.001). Conclusions: RCM is able to diagnose BCCs mimicking melanoma at dermoscopy and seems able to identify sBCCs and nsBCCs.

Reflectance confocal microscopy analysis of equivocal melanocytic lesions with severe regression

2017 ◽  
Vol 24 (1) ◽  
pp. 9-15 ◽  
Author(s):  
M. Agozzino ◽  
A. Ferrari ◽  
C. Cota ◽  
C. Franceschini ◽  
P. Buccini ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions ◽  
Microscopy Analysis ◽  
Confocal Microscopy Analysis

In Vivo Reflectance Confocal Microscopy of Halo Nevus

2013 ◽  
Vol 17 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Rodrigo J. Schwartz ◽  
Karla Vera ◽  
Nelson Navarrete ◽  
Pedro Lobos
Keyword(s):  
High Resolution ◽  
Malignant Melanoma ◽  
Confocal Microscopy ◽  
Skin Diseases ◽  
Dermal Papilla ◽  
Reflectance Confocal Microscopy ◽  
Melanocytic Lesions ◽  
Global Patterns ◽  
Dermal Papillae

Background: RCM (reflectance confocal microscopy) is a noninvasive, high-resolution technology that has been proven to improve the diagnostic accuracy over clinical examination in several skin diseases. Objective: The aim of this article is to describe the morphologic features of halo nevi (HN) observed with RCM and correlate them with their dermoscopic characteristics. Method: Nine patients with the clinical diagnosis of HN were assessed with RCM. A second assessment was performed up to 12 months later. Dermoscopic global patterns were obtained and correlated with the RCM findings. Results: In five (55.6%) cases, pagetoid cells were observed. Nonedged dermal papilla and junctional thickening were found in three (33%) cases. Nucleated cells in the dermal papillae and plump bright cells were observed in seven (77.8%) and six (66.7%) cases, respectively. Conclusion: Our study shows that HN observed by RCM can show atypical features that overlap with those observed on atypical melanocytic lesions and malignant melanoma.

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