Use of Intravenous Lipids: What Do the Guidelines Say?

2014 ◽  
pp. 163-171 ◽  
Author(s):  
Pierre Singer ◽  
Miriam Theilla ◽  
Jonathan Cohen
Keyword(s):  
Intravenous Lipids

scholarly journals 59 Short term elevation of cholesterol level in neonatal life and long term changes in aortic stiffness: insights from use of intravenous lipids

Heart ◽  
2011 ◽  
Vol 97 (Suppl 1) ◽  
pp. A37-A38
Author(s):  
A. J. Lewandowski ◽  
M. Lazdam ◽  
E. Davis ◽  
R. Poole ◽  
J. Diesch ◽  
...  
Keyword(s):  
Cholesterol Level ◽  
Aortic Stiffness ◽  
Short Term ◽  
Neonatal Life ◽  
Long Term Changes ◽  
Intravenous Lipids

Intravenous lipids in newborn lungs

1989 ◽  
Vol 17 (5) ◽  
pp. 430-436 ◽  
Author(s):  
CATHY HAMMERMAN ◽  
MARY JANE ARAMBURO ◽  
VAL HILL
Keyword(s):  
Intravenous Lipids

scholarly journals Intravenous Lipids for Preterm Infants: A Review

2015 ◽  
Vol 9 ◽  
pp. CMPed.S21161 ◽  
Author(s):  
Ghassan S. A. Salama ◽  
Mahmmoud A.F. Kaabneh ◽  
Mai N. Almasaeed ◽  
Mohammad I.A. Alquran
Keyword(s):  
Clinical Care ◽  
Premature Neonate ◽  
Extremely Low Birth Weight ◽  
Cns Injury ◽  
Lipid Biochemistry ◽  
Clinical Practices ◽  
Low Birth Weight Infants ◽  
Aggressive Approach ◽  
Intravenous Lipids ◽  
Controversial Area

Extremely low birth weight infants (ELBW) are born at a time when the fetus is undergoing rapid intrauterine brain and body growth. Continuation of this growth in the first several weeks postnatally during the time these infants are on ventilator support and receiving critical care is often a challenge. These infants are usually highly stressed and at risk for catabolism. Parenteral nutrition is needed in these infants because most cannot meet the majority of their nutritional needs using the enteral route. Despite adoption of a more aggressive approach with amino acid infusions, there still appears to be a reluctance to use early intravenous lipids. This is based on several dogmas that suggest that lipid infusions may be associated with the development or exacerbation of lung disease, displace bilirubin from albumin, exacerbate sepsis, and cause CNS injury and thrombocytopena. Several recent reviews have focused on intravenous nutrition for premature neonate, but very little exists that provides a comprehensive review of intravenous lipid for very low birth and other critically ill neonates. Here, we would like to provide a brief basic overview, of lipid biochemistry and metabolism of lipids, especially as they pertain to the preterm infant, discuss the origin of some of the current clinical practices, and provide a review of the literature, that can be used as a basis for revising clinical care, and provide some clarity in this controversial area, where clinical care is often based more on tradition and dogma than science.

scholarly journals SAFETY AND QUALITY OF INTRAVENOUS LIPIDS FOR NEWBORNS: EFFECTS ON CRITICAL DISEASES AND METABOLIC DISORDERS (PART II)

2021 ◽  
Vol 11 (4(42)) ◽  
pp. 68-74
Author(s):  
I. Anikin ◽  
V. Snisar
Keyword(s):  
Birth Weight ◽  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Intraventricular Hemorrhage ◽  
Metabolic Disorders ◽  
Ductus Arteriosus ◽  
Lipid Emulsions ◽  
Intravenous Lipids ◽  
Patent Ductus

Premature birth and its complications cause stress in newborns, which restrains their physical growth for several weeks after birth and is associated with chronic morbidity and neurological disability in the future. Preterm infants face such difficulties as respiratory distress, cardiovascular disease, gastrointestinal dysfunction and very low birth weight. Most complications in newborns are associated with oxidative stress that develops during the early period of growth. The formation of free radicals entails oxidative damage to many organs and systems of the body and is the main factor responsible for the development of typical diseases of preterm infants, such as bronchopulmonary dysplasia, patent ductus arteriosus, retinopathy of prematurity, necrotizing enterocolitis, intraventricular hemorrhage, and respiratory distress syndrome. Premature infants depend on adequate early parenteral nutrition, which not only guarantees they will survive but also ensures positive health outcomes later in life. Early use of intravenous lipids helps to prevent essential fatty acid deficiencies, provides energy and substrates for cell membrane synthesis, which are important for the growth and development of infants with very low and extremely low birth weight. This publication represents data on the effect of intravenous lipids on critical conditions and metabolic disorders in newborns. Literature sources are analyzed and the existing evidence of the possible influence of lipid emulsions on critical diseases in newborns is presented: intraventricular hemorrhage; necrotizing enterocolitis, patent ductus arteriosus and thrombocytopenia; glucose metabolism (hypo- and hyperglycemia); hyperbilirubinemia and chronic liver damage. The literature review is aimed at finding optimal strategies for the use of lipid emulsions in intensive care of newborns to improve the quality of care for premature infants. The purpose of this work is to analyze the results of published studies and systematize data on the feasibility and safety of lipid emulsions used in newborns with critical diseases of the perinatal period.

An evaluation of methods to monitor infants receiving intravenous lipids

1979 ◽  
Vol 94 (2) ◽  
pp. 197-200 ◽  
Author(s):  
Richard L. Schreiner ◽  
Melvin R. Glick ◽  
Carleton D. Nordschow ◽  
Edwin L. Gresham
Keyword(s):  
Intravenous Lipids ◽  
Evaluation Of Methods
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