An Overview of the Natural History of Inflammatory Bowel Diseases

2014 ◽  
Vol 32 (4) ◽  
pp. 320-327 ◽  
Author(s):  
Eugeni Domènech ◽  
Míriam Mañosa ◽  
Eduard Cabré
Keyword(s):  
Natural History ◽  
Inflammatory Bowel Diseases ◽  
Bowel Diseases ◽  
History Of ◽  
Inflammatory Bowel

scholarly journals Early Life Environment and Natural History of Inflammatory Bowel Diseases

2014 ◽  
Vol 109 ◽  
pp. S486
Author(s):  
Abra Guo ◽  
Robin Wilson ◽  
Betsy Stevens ◽  
Caitlin Russell ◽  
Melissa Cohen ◽  
...  
Keyword(s):  
Natural History ◽  
Inflammatory Bowel Diseases ◽  
Early Life ◽  
Early Life Environment ◽  
Bowel Diseases ◽  
History Of ◽  
Inflammatory Bowel

scholarly journals Impact of Coexistent Celiac Disease on Phenotype and Natural History of Inflammatory Bowel Diseases

2013 ◽  
Vol 108 (7) ◽  
pp. 1123-1129 ◽  
Author(s):  
Emily C Oxford ◽  
Deanna D Nguyen ◽  
Jenny Sauk ◽  
Joshua R Korzenik ◽  
Vijay Yajnik ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Natural History ◽  
Inflammatory Bowel Diseases ◽  
Bowel Diseases ◽  
History Of ◽  
Inflammatory Bowel

scholarly journals Histological Hallmarks of Mucosal Healing in Inflammatory Bowel Diseases in the Era of Monoclonal Antibodies Therapy: New Insights and Perspectives

Diagnostics ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1570
Author(s):  
Gerardo Cazzato ◽  
Anna Colagrande ◽  
Valeria Andriola ◽  
Teresa Lettini ◽  
Sebastiano Cicco ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Natural History ◽  
Inflammatory Bowel Diseases ◽  
Careful Analysis ◽  
Mucosal Healing ◽  
Level Of Evidence ◽  
Clinical Endpoints ◽  
Bowel Diseases ◽  
History Of ◽  
Inflammatory Bowel

Background: Chronic inflammatory bowel diseases (IBDs) are gaining increasing attention, both because they can severely reduce the quantity and quality of life, and because the advent of monoclonal antibodies has profoundly changed the natural history of these diseases. In recent years, the concept of mucosal healing has assumed a certain importance, and there are more and more clinical and pharmacological trials that consider this parameter among their endpoints, so much so that it may soon be included among the desirable clinical outcomes of patients with IBD. Methods: We performed a literature review of the Pubmed, Medline, and Web of Science (WoS) databases. Results: We selected 88 articles and then removed 6 duplicates; the final sample after accurate application of the inclusion criteria numbered 73 articles, with a level of evidence rating of three or four, according to Oxfords Evidence-based medicine. Our aim was to study the histological impact of monoclonal antibody therapies on mucosal healing, taking into consideration the few studies present in the literature. To perform this review, we compared studies that examined patients with Crohn’s disease (CD) and/or ulcerative colitis (UC) undergoing monoclonal therapy versus patients undergoing other non-biological therapies (PICO statements). Conclusions: We try to delineate how monoclonal antibodies have changed the natural history of IBD, acting at the microscopic level, and we believe that a careful analysis of the histopathology and the definition of the objective criteria for “Mucosa Healing” should enable this concept to be included among the clinical endpoints of patients affected by IBD, thus contributing to a better therapeutic management of these patients.

Epidemiology and Natural History of Inflammatory Bowel Diseases

2011 ◽  
Vol 140 (6) ◽  
pp. 1785-1794.e4 ◽  
Author(s):  
Jacques Cosnes ◽  
Corinne Gower–Rousseau ◽  
Philippe Seksik ◽  
Antoine Cortot
Keyword(s):  
Natural History ◽  
Inflammatory Bowel Diseases ◽  
Bowel Diseases ◽  
History Of ◽  
Inflammatory Bowel

scholarly journals Mo1249 Impact of Co-Existent Celiac Disease on Phenotype and Natural History of Inflammatory Bowel Diseases

2013 ◽  
Vol 144 (5) ◽  
pp. S-617-S-618
Author(s):  
Emily Oxford ◽  
Deanna D. Nguyen ◽  
Jenny Sauk ◽  
Joshua R. Korzenik ◽  
Vijay Yajnik ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Natural History ◽  
Inflammatory Bowel Diseases ◽  
Bowel Diseases ◽  
History Of ◽  
Inflammatory Bowel

scholarly journals Early life environment and natural history of inflammatory bowel diseases

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Abra Y Guo ◽  
Betsy W Stevens ◽  
Robin G Wilson ◽  
Caitlin N Russell ◽  
Melissa A Cohen ◽  
...  
Keyword(s):  
Natural History ◽  
Inflammatory Bowel Diseases ◽  
Early Life ◽  
Early Life Environment ◽  
Bowel Diseases ◽  
History Of ◽  
Inflammatory Bowel

Sa1115 Natural History of Non-Severe Inflammatory Bowel Diseases At Diagnosis

2014 ◽  
Vol 146 (5) ◽  
pp. S-203-S-204
Author(s):  
Cyrielle Pirard ◽  
Edouard Louis ◽  
Reenaers Catherine
Keyword(s):  
Natural History ◽  
Inflammatory Bowel Diseases ◽  
Bowel Diseases ◽  
History Of ◽  
Inflammatory Bowel
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