Prestroke Dementia: Characteristics and Clinical Features in Consecutive Series of Patients

2014 ◽  
Vol 71 (3-4) ◽  
pp. 148-154 ◽  
Author(s):  
Salvatore Caratozzolo ◽  
Maddalena Riva ◽  
Barbara Vicini Chilovi ◽  
Erica Cerea ◽  
Giulia Mombelli ◽  
...  
Keyword(s):  
Clinical Features ◽  
Consecutive Series ◽  
Prestroke Dementia

scholarly journals Familial Parkinson’s Disease: A Clinical Genetic Analysis

1995 ◽  
Vol 22 (4) ◽  
pp. 272-279 ◽  
Author(s):  
Vincenzo Bonifati ◽  
Edito Fabrizio ◽  
Nicola Vanacore ◽  
Michele De Mari ◽  
Giuseppe Meco
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Family History ◽  
Genetic Analysis ◽  
Clinical Features ◽  
Consecutive Series ◽  
Onset Age ◽  
Clinical Genetic ◽  
Clinical Series ◽  
Familial Parkinson’S Disease

AbstractObjectiveTo study the frequency, clinical features and clinical genetics of familial Parkinson’s disease (PD).MethodsFamily history for PD and tremors was studied in 100 consecutive PD cases. Spouses served as controls. Clinical features were compared between personally verified familial and sporadic PD cases, from the same consecutive clinical series. Clinical genetic analysis was performed in a larger group of non-consecutive multicase PD families.ResultsFamily history for PD was positive in 24% of consecutive PD cases and in 6% of spouse controls (p < 0.001). When family history for isolated tremor is also considered, the number of positive cases rises to 43% compared with 9% in controls (p < 0.001). Nine of the consecutive cases had at least one living affected relative, for a total of 20 familial PD cases. These familial cases showed an earlier onset age when compared with sporadic ones from the same consecutive series. Within 22 non-consecutive PD families with at least two living and personally examined PD cases (total 52 PD cases), the crude segregation ratios were similar for parents and siblings and the lifetime cumulative risks approached 0.4 in siblings and tended to be comparable, but at later ages, in parents. Ancestral relatives were all unilaterally distributed. In some families, anticipation of onset age in new generations was observed.ConclusionsThe frequency of positive family history for PD and for PD and tremor is higher among PD cases than controls. Familial and sporadic PD only differ in onset age. The clinical genetic analyses support autosomal dominant inheritance with strongly age-related penetrance as most likely in familial PD.

Chronic histiocytic intervillositis of unknown etiology: Clinical features in a consecutive series of 69 cases

Placenta ◽  
2011 ◽  
Vol 32 (2) ◽  
pp. 140-145 ◽  
Author(s):  
V. Marchaudon ◽  
L. Devisme ◽  
S. Petit ◽  
H. Ansart-Franquet ◽  
P. Vaast ◽  
...  
Keyword(s):  
Clinical Features ◽  
Unknown Etiology ◽  
Consecutive Series

Fibrosing cholestatic hepatitis: Clinical features, outcome and response to interferon and ribavirin

2001 ◽  
Vol 120 (5) ◽  
pp. A563-A564
Author(s):  
M ISMAIL ◽  
I DABOUL ◽  
B WATERS ◽  
J FLECKENSTEIN ◽  
S VERA ◽  
...  
Keyword(s):  
Clinical Features ◽  
Cholestatic Hepatitis
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