Carcinosarcoma of the Female Urethra

2014 ◽  
Vol 96 (3) ◽  
pp. 370-372
Author(s):  
L. D'Arrigo ◽  
A. Costa ◽  
F. Fraggetta ◽  
M. Pennisi ◽  
P. Pepe ◽  
...  

Carcinosarcoma is a rare malignant tumor with a biphasic morphology characterized by the presence of a malignant epithelial and mesenchymal component. It has been reported in many organs, including the genitourinary tract. We describe a case of a 47-year-old woman admitted to our hospital for history of recurrent urinary tract infection, dysuria and discharge of bloody fluid from the urethra at the end of urination. A tender palpable mass under the anterior vaginal wall was found and pathological examination showed a urethral carcinosarcoma. The histopathogenetic hypothesis and clinical management were considered in this report.

2017 ◽  
Vol 99 (2) ◽  
pp. 155-160 ◽  
Author(s):  
KV Manley ◽  
R Hubbard ◽  
D Swallow ◽  
W Finch ◽  
SJ Wood ◽  
...  

INTRODUCTION The aim of this study was to investigate the prevalence of risk factors for primary squamous cell carcinoma (SCC) of the bladder. MATERIALS A total of 90 cases of primary SCC of the bladder were identified through multicentre analysis. Patient demographics, stage and grade of cancer at presentation, management and outcomes were recorded. The presence of known risk factors (catheter use, neuropathic bladder, smoking history, recurrent urinary tract infection and bladder stones) was also documented. RESULTS Over half of the patients had at least one identifiable risk factor for the development of primary bladder SCC: 13.9% of patients had a history of catheter use (clean intermittent self-catheterisation [CISC] in 11.1%), 10.0% of patients had a neuropathic bladder, 27.8% were smokers or ex-smokers and 20.0% had a documented history of recurrent urinary tract infection. Statistical analysis of the results showed no association between risk factors and grade of tumour at presentation. CONCLUSIONS These data further support the association between primary bladder SCC and several of the well documented risk factors for its development. Chronic use of CISC may confer a greater risk for development of SCC than thought previously. Further evidence of the role of CISC in primary SCC is required to justify routine screening and to determine exactly when surveillance of the bladder should begin for this group of patients.


2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Ariella Friedman ◽  
Cortney Wolfe-Christensen ◽  
Amanda Toffoli ◽  
Teresa Jones ◽  
Thomas Slovis ◽  
...  

2017 ◽  
Vol 1 (2) ◽  
pp. 52-56 ◽  
Author(s):  
Kafil Akhtar ◽  
Mahboob Hasan ◽  
Kiran Alam ◽  
Mohd Talha ◽  
Atia Z Rab

Xanthogranulomatous pyelonephritis is an uncommon chronic destructive disease process of renal parenchyma, associated with recurrent urinary tract infection. It is seen predominantly in females with no age specificity. The most common symptoms are flank or abdominal pain, fever, palpable mass, and gross hematuria. The common laboratory findings are leukocytosis and anemia. Urine cultures most often reveal Escherichia coli and Proteus mirabilis. Computed tomography is the mainstay of diagnostic imaging for xanthogranulomatous pyelonephritis. Histologically, xanthogranulomatous pyelonephritis presents a granulomatous inflammatory infiltrate mainly composed of lymphocytes, plasma cells, foamy histiocytes, and multinucleated giant cells. The differential diagnosis includes clear cell renal cell carcinoma, sarcomatoid renal cell carcinoma, leiomyosarcoma, malakoplakia, tuberculosis, and interstitial nephritis. Treatment includes antibiotics and surgery. In this article, we report a case of xanthogranulomatous pyelonephritis in a 38-year-old male patient with recurrent urinary tract infection.


2012 ◽  
Vol 8 (1) ◽  
pp. 44-47
Author(s):  
A Agarwal ◽  
G Sigdel ◽  
SR KC ◽  
P Shrestha ◽  
WK Belokar

Multiple vesical calculi are rarely seen in urological practice. Males are affected more than the females. Vesical calculi are usually secondary to bladder outlet obstruction. These patients present with recurrent urinary tract infection, haematuria or with retention of urine. We report a 43 years male patient who presented with acute urinary retention. He had history of trauma over perineal region three years back following which he had recurrent urinary tract infection and thinning of stream. USG abdomen revealed normal upper urinary tract with echogenic debris in partially filled urinary bladder. Renal function test was with in normal limit. Per urethral catheterization failed and over antibiotic cover, patient was posted for cystourethroscopy followed by suprapubic cystostomy under spinal anaesthesia. Membranous urethral stricture found during urethroscopy could be managed by optical internal urethrotomy. On cystoscopy whole of bladder was filled with thick pus like material with multiple large urinary bladder calculi. Open cystolithotomy was done and we were surprised to see 356 stones of various size and shape after removal. Patient made uneventful recovery and discharged after 12 days of hospital stay. Journal of College of Medical Sciences-Nepal,2012,Vol-8,No-1, 44-47 DOI: http://dx.doi.org/10.3126/jcmsn.v8i1.6825


2006 ◽  
Vol 176 (5) ◽  
pp. 2050-2054 ◽  
Author(s):  
Louisa Kwok ◽  
Ann E. Stapleton ◽  
Walter E. Stamm ◽  
Sharon L. Hillier ◽  
Cheryl L. Wobbe ◽  
...  

2013 ◽  
Vol 29 (6) ◽  
pp. 639-643 ◽  
Author(s):  
Ariella A. Friedman ◽  
Cortney Wolfe-Christensen ◽  
Amanda Toffoli ◽  
David E. Hochsztein ◽  
Jack S. Elder ◽  
...  

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