Can the Tall Cell Variant of Papillary Thyroid Carcinoma Be Distinguished from the Conventional Type in Fine Needle Aspirates? A Cytomorphologic Study with Assessment of Diagnostic Accuracy

2013 ◽  
Vol 57 (5) ◽  
pp. 534-542 ◽  
Author(s):  
Hui Guan ◽  
Christopher J. VandenBussche ◽  
Yener S. Erozan ◽  
Dorothy L. Rosenthal ◽  
Armanda D. Tatsas ◽  
...  
2020 ◽  
Vol 10 (1) ◽  
pp. 70
Author(s):  
Alessandro Longheu ◽  
Gian Luigi Canu ◽  
Federico Cappellacci ◽  
Enrico Erdas ◽  
Fabio Medas ◽  
...  

Background: The aim of this retrospective study was to investigate clinical and pathological characteristics of the tall cell variant of papillary thyroid carcinoma compared to conventional variants. Methods: The clinical records of patients who underwent surgical treatment between 2009 and 2015 were analyzed. The patients were divided into two groups: those with a histopathological diagnosis of tall cell papillary carcinoma were included in Group A, and those with a diagnosis of conventional variants in Group B. Results: A total of 35 patients were included in Group A and 316 in Group B. All patients underwent total thyroidectomy. Central compartment and lateral cervical lymph node dissection were performed more frequently in Group A (42.8% vs. 18%, p = 0.001, and 17.1% vs. 6.9%, p = 0.04). Angiolymphatic invasion, parenchymal invasion, extrathyroidal extension, and lymph node metastases were more frequent in Group A, and the data reached statistical significance. Local recurrence was more frequent in Group A (17.1% vs. 6.3%, p = 0.02), with two patients (5.7%) in Group A showing visceral metastases, whereas no patient in Group B developed metastatic cancer (p = 0.009). Conclusions: Tall cell papillary carcinoma is the most frequent aggressive variant of papillary thyroid cancer. Tall cell histology represents an independent poor prognostic factor compared to conventional variants.


2019 ◽  
pp. 225-228
Author(s):  
Miyoko Higuchi ◽  
Mitsuyoshi Hirokawa ◽  
Seiji Kuma

2018 ◽  
Vol 30 (1) ◽  
pp. 43-48 ◽  
Author(s):  
Kristine S. Wong ◽  
Sara E. Higgins ◽  
Ellen Marqusee ◽  
Matthew A. Nehs ◽  
Trevor Angell ◽  
...  

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