Agreement between Time-Domain and Spectral-Domain Optical Coherence Tomography in the Assessment of Macular Thickness in Patients with Idiopathic Macular Telangiectasia Type 2

2013 ◽  
Vol 230 (3) ◽  
pp. 144-150 ◽  
Author(s):  
Raeba Mathew ◽  
Sobha Sivaprasad ◽  
Daniela Florea ◽  
Irene Leung ◽  
Ferenc Sallo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Time Domain ◽  
Macular Thickness ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Macular Telangiectasia ◽  
Macular Telangiectasia Type 2 ◽  
Idiopathic Macular Telangiectasia

Outer Retinal Hyperreflective Spots on Spectral-Domain Optical Coherence Tomography in Macular Telangiectasia Type 2

Ophthalmology ◽  
2010 ◽  
Vol 117 (11) ◽  
pp. 2162-2168 ◽  
Author(s):  
Sönke Baumüller ◽  
Peter Charbel Issa ◽  
Hendrik P.N. Scholl ◽  
Steffen Schmitz-Valckenberg ◽  
Frank G. Holz
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Macular Telangiectasia ◽  
Macular Telangiectasia Type 2

Spectral-Domain Optical Coherence Tomography Measurements of Choroidal Thickness and Outer Retinal Disruption in Macular Telangiectasia Type 2

2015 ◽  
Vol 46 (2) ◽  
pp. 162-170 ◽  
Author(s):  
Renata Portella Nunes ◽  
Raquel Goldhardt ◽  
Carlos Alexandre de Amorim Garcia Filho ◽  
Mariana R. Thorell ◽  
Ashkan M. Abbey ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Macular Telangiectasia ◽  
Macular Telangiectasia Type 2

scholarly journals Idiopathic Macular Telangiectasia Type 2 and Its Relationship with Macular Pigment Optical Density

2019 ◽  
pp. 01-12
Author(s):  
Chris Putnam
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Macular Pigment ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Macular Telangiectasia ◽  
Layer Deposition ◽  
Macular Telangiectasia Type 2 ◽  
Idiopathic Macular Telangiectasia

Idiopathic macular telangiectasia type 2 (IMT2) is a relatively uncommon clinical condition with an estimated prevalence of 1% within the general population. This condition can be challenging to precisely identify in early stages but advancements in clinical imaging to include fluorescein angiography and optical coherence tomography angiography (OCTA) can allow for timely diagnosis and prompt intervention that may leads to improved long-term clinical outcomes. Emerging literature has recognized the role of macular pigment (MP) in IMT2 in terms of Henle fiber layer deposition mechanisms and potential mitigation of inflammatory and oxidative stress. Primary care optometrists are in a unique position to facilitate early detection and manage through close evaluation and individualized lutein and zeaxanthin supplementation. Keywords: Idiopathic macular telangiectasia type 2; Macular pigment; Spectral domain optical coherence tomography angiography

scholarly journals Optical Coherence Tomography Angiography of Macular Telangiectasia Type 2 with Associated Subretinal Neovascular Membrane

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Victor M. Villegas ◽  
Jaclyn L. Kovach
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Subretinal Neovascularization ◽  
Macular Telangiectasia ◽  
Capillary Plexus ◽  
Macular Telangiectasia Type 2 ◽  
Subretinal Neovascular Membrane ◽  
Choroidal Vasculature

Optical coherence tomography angiography (OCTA) is a recently established noninvasive technology for evaluation of the retinal and choroidal vasculature. The literature regarding the findings in macular telangiectasia type 2 (MacTel2) is scarce. We report the OCTA findings associated with a subject with MacTel2 and secondary subretinal neovascularization (SNV). The commercially available Cirrus 5000 with AngioPlex (Zeiss, Jena, Germany) was used, without any subsequent image modification or processing. Subretinal neovascularization was detectable with OCTA at the level of the outer retina and choriocapillaris. Microvascular abnormalities associated with MacTel2 were present mostly in the deep capillary plexus of the retina temporally.

scholarly journals Deep learning-based classification and segmentation of retinal cavitations on optical coherence tomography images of macular telangiectasia type 2

2020 ◽  
pp. bjophthalmol-2020-317131
Author(s):  
Jessica Loo ◽  
Cindy X Cai ◽  
John Choong ◽  
Emily Y Chew ◽  
Martin Friedlander ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Performance Metrics ◽  
Alternative Methods ◽  
Dice Similarity Coefficient ◽  
Optical Coherence ◽  
Time Points ◽  
Macular Telangiectasia ◽  
Macular Telangiectasia Type 2 ◽  
Over Time

AimTo develop a fully automatic algorithm to segment retinal cavitations on optical coherence tomography (OCT) images of macular telangiectasia type 2 (MacTel2).MethodsThe dataset consisted of 99 eyes from 67 participants enrolled in an international, multicentre, phase 2 MacTel2 clinical trial (NCT01949324). Each eye was imaged with spectral-domain OCT at three time points over 2 years. Retinal cavitations were manually segmented by a trained Reader and the retinal cavitation volume was calculated. Two convolutional neural networks (CNNs) were developed that operated in sequential stages. In the first stage, CNN1 classified whether a B-scan contained any retinal cavitations. In the second stage, CNN2 segmented the retinal cavitations in a B-scan. We evaluated the performance of the proposed method against alternative methods using several performance metrics and manual segmentations as the gold standard.ResultsThe proposed method was computationally efficient and accurately classified and segmented retinal cavitations on OCT images, with a sensitivity of 0.94, specificity of 0.80 and average Dice similarity coefficient of 0.94±0.07 across all time points. The proposed method produced measurements that were highly correlated with the manual measurements of retinal cavitation volume and change in retinal cavitation volume over time.ConclusionThe proposed method will be useful to help clinicians quantify retinal cavitations, assess changes over time and further investigate the clinical significance of these early structural changes observed in MacTel2.

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