scholarly journals UK Renal Registry 15th Annual Report: Chapter 5 Survival and Causes of Death of UK Adult Patients on Renal Replacement Therapy in 2011: National and Centre-Specific Analyses

2013 ◽  
Vol 123 (s1) ◽  
pp. 93-123 ◽  
Author(s):  
Retha Steenkamp ◽  
Catriona Shaw ◽  
Terry Feest
Keyword(s):  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Causes Of Death ◽  
Annual Report ◽  
Adult Patients

scholarly journals Chapter 6: Survival and Causes of Death of UK Adult Patients on Renal Replacement Therapy in 2009: National and Centre-Specific Analyses

2011 ◽  
Vol 119 (s2) ◽  
pp. c107-c134 ◽  
Author(s):  
Clare Castledine ◽  
Retha Steenkamp ◽  
Terry Feest ◽  
Charles R.V. Tomson
Keyword(s):  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Causes Of Death ◽  
Adult Patients

scholarly journals Renal replacement therapy in adult dominant polycystic kidney disease - multicentre study

2008 ◽  
Vol 136 (Suppl. 4) ◽  
pp. 287-293
Author(s):  
Visnja Lezaic ◽  
Vladimir Ostric ◽  
Gordana Popovic ◽  
Milja Vukoje ◽  
Branislava Dragoljic ◽  
...  
Keyword(s):  
Renal Replacement Therapy ◽  
Kidney Disease ◽  
Replacement Therapy ◽  
Polycystic Kidney Disease ◽  
Causes Of Death ◽  
Family Members ◽  
Favourable Outcome ◽  
Polycystic Kidney ◽  
Adult Polycystic Kidney Disease ◽  
Av Fistula

INTRODUCTION. Adult polycystic kidney disease (APKD) is the most common hereditary kidney disease in humans. The course of the disease is accompanied by numerous complications. OBJECTIVE The aim was to assess the prevalence, clinical course and outcome of adult dominant polycystic kidney disease (ADPKD) patients on renal replacement therapy. METHOD. Medical data on 700 haemodialyzed (HD) and 500 transplanted patients treated in 10 Serbian centres from 1996 to 2000 were retrospectively analyzed. While ADPKD patients accounted for 13% of HD patients in Serbia in 2000, in the period between 1996 and 2000, the percent of patients with ADPKD in the population of patients starting HD in 8 examined centres changed from 13.5% to 6.9%. RESULTS. The total number of 180 ADPKD patients on HD was analyzed (96 males; aged 55 years at HD onset). Their HD lasted between 1 and 22 years: males started HD 1.3 years earlier and spent on HD 1.1 years less than females. In 53% of HD patients one or more family members had ADPKD but the cause of death was unknown for many family members. Hypertension was present in 75% of ADPKD patients, anaemia in 37% and other organ involvement (usually liver) was found in 53 patients. Fifty patients experienced AV fistula thrombosis and a vascular prosthesis had to be used in 9 of them. A hundred and two HD patients died (aged between 38 and 78 years, on HD for 5.3 years). The causes of death were stroke (19.6%), cardiovascular diseases (29%), infections, while 5% of patients died with the picture of acute abdomen. Among 500 transplanted patients, there were 20 patients with ADPKD (11 males, ages between 35 and 56 years at the time of transplantation) and 14 of them received graft from cadaver donor. Uni- or bilateral nephrectomy was done in 4 patients in the pretransplant preparation, and in another two early after transplantation due to urinary infection. Three patients restarted HD in the first 3 months after transplantation due to acute tubular necrosis and 10 patients died 56.5 months after the transplantation. The known causes of death were cardiovascular disease (3 patients), severe gastrointestinal bleeding (2 patients), infection (2 patients) and cancer (2 patients). CONCLUSION. The obtained results showed that it was possible to provide a favourable outcome of patients with APBB on renal replacement therapy in spite of numerous complications.

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