Human Unrestricted Somatic Stem Cell Administration Fails to Protect Nude Mice from Cisplatin-Induced Acute Kidney Injury

2013 ◽  
Vol 123 (3-4) ◽  
pp. 11-21 ◽  
Author(s):  
Yousof Gheisari ◽  
Naser Ahmadbeigi ◽  
Seyed Hamid Aghaee-Bakhtiari ◽  
Seyed Mahdi Nassiri ◽  
Saeid Amanpour ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Stem Cell ◽  
Nude Mice ◽  
Kidney Injury ◽  
Somatic Stem Cell ◽  
Unrestricted Somatic Stem Cell

scholarly journals Negative Regulation of TGFβ Signaling by Stem Cell Antigen-1 Protects against Ischemic Acute Kidney Injury

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0129561 ◽  
Author(s):  
Troy D. Camarata ◽  
Grant C. Weaver ◽  
Alexandr Vasilyev ◽  
M. Amin Arnaout
Keyword(s):  
Acute Kidney Injury ◽  
Stem Cell ◽  
Kidney Injury ◽  
Negative Regulation ◽  
Tgfβ Signaling ◽  
Cell Antigen ◽  
Ischemic Acute Kidney Injury

Hematopoietic stem cell transplantation and acute kidney injury in children: A comprehensive review

2017 ◽  
Vol 21 (4) ◽  
pp. e12935 ◽  
Author(s):  
Rupesh Raina ◽  
Nicholas Herrera ◽  
Vinod Krishnappa ◽  
Sidharth Kumar Sethi ◽  
Akash Deep ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Kidney Injury ◽  
Hematopoietic Stem ◽  
Comprehensive Review

Generation of Urine-Derived Induced Pluripotent Stem Cell Line from Patients with Acute Kidney Injury

2021 ◽  
Vol 23 (5) ◽  
pp. 290-303
Author(s):  
Yong Jin ◽  
Manling Zhang ◽  
Meishuang Li ◽  
Hao Zhang ◽  
Feng Zhang ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Stem Cell ◽  
Cell Line ◽  
Pluripotent Stem Cell ◽  
Kidney Injury ◽  
Induced Pluripotent Stem Cell ◽  
Stem Cell Line ◽  
Induced Pluripotent

scholarly journals Stem cell-based treatment of kidney diseases

2020 ◽  
Vol 245 (10) ◽  
pp. 902-910
Author(s):  
Binbin Pan ◽  
Guoping Fan
Keyword(s):  
Chronic Kidney Disease ◽  
Stem Cells ◽  
Acute Kidney Injury ◽  
Stem Cell ◽  
Kidney Disease ◽  
Cell Therapy ◽  
Kidney Diseases ◽  
Kidney Injury ◽  
Great Promise ◽  
Kidney Organoids

Kidney dysfunction, including chronic kidney disease and acute kidney injury, is a globally prevalent health problem. However, treatment regimens are still lacking, especially for conditions involving kidney fibrosis. Stem cells hold great promise in the treatment of chronic kidney disease and acute kidney injury, but success has been hampered by insufficient incorporation of the stem cells in the injured kidney. Thus, new approaches for the restoration of kidney function after acute or chronic injury have been explored. Recently, kidney organoids have emerged as a useful tool in the treatment of kidney diseases. In this review, we discuss the mechanisms and approaches of cell therapy in acute kidney injury and chronic kidney disease, including diabetic kidney disease and lupus nephritis. We also summarize the potential applications of kidney organoids in the treatment of kidney diseases. Impact statement Stem cells hold great promise in regenerative medicine. Pluripotent stem cells have been differentiated into kidney organoids to understand human kidney development and to dissect renal disease mechanisms. Meanwhile, recent studies have explored the treatment of kidney diseases using a variety of cells, including mesenchymal stem cells and renal derivatives. This mini-review discusses the diverse mechanisms underlying current renal disease treatment via stem cell therapy. We postulate that clinical applications of stem cell therapy for kidney diseases can be readily achieved in the near future.

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