scholarly journals Use of Color Doppler Ultrasonography to Measure Thyroid Blood Flow and Differentiate Graves' Disease from Painless Thyroiditis

2013 ◽  
Author(s):  
Tetsuya Hiraiwa ◽  
Naoyuki Tsujimoto ◽  
Keiji Tanimoto ◽  
Jungo Terasaki ◽  
Nobuyuki Amino ◽  
...  
Keyword(s):  
Blood Flow ◽  
Doppler Ultrasonography ◽  
Color Doppler ◽  
Color Doppler Ultrasonography ◽  
Graves Disease ◽  
Painless Thyroiditis

scholarly journals Diagnostic Utility of Mean Peak Systolic Velocity of Superior Thyroid Artery in Differentiating Graves’ Disease from Thyroiditis

2021 ◽  
Author(s):  
Pradosh K. Sarangi ◽  
Sasmita Parida ◽  
Swayamsidha Mangaraj ◽  
Binoy K. Mohanty ◽  
Jayashree Mohanty ◽  
...  
Keyword(s):  
Blood Flow ◽  
Sensitivity And Specificity ◽  
Doppler Ultrasonography ◽  
Color Doppler ◽  
Peak Systolic Velocity ◽  
Color Doppler Ultrasonography ◽  
Superior Thyroid Artery ◽  
Control Group ◽  
Graves Disease ◽  
Flow Parameters

Abstract Background Differentiating Graves’ disease from thyroiditis can be at times clinically challenging. The gold standard test (thyroid nuclear imaging scan) is expensive, not routinely available, and has radiation exposure. Color Doppler ultrasonography of thyroid represents a suitable alternate which can be used for differentiating these conditions by studying thyroid blood flow parameters. Aim We aimed to investigate the use of thyroid blood flow parameters’ assessment of the superior thyroid artery (STA) and common carotid artery (CCA) with color Doppler ultrasonography for differentiating Graves’ disease from thyroiditis. Materials and Methods This is a cross-sectional study on 111 patients with newly diagnosed thyrotoxicosis (82 with Graves’ disease and 29 with thyroiditis) and 45 years of age and sex-matched healthy controls. All patients underwent detailed clinical and necessary investigations. Color Doppler ultrasonography of the thyroid gland and spectral flow analysis of both superior thyroid arteries was done using standard protocol. Sensitivity and specificity for mean peak systolic velocity of STA (STA-PSV) cut-offs were calculated using receiver operating characteristic curves. Results Patients with Graves’ disease have significantly higher free tri-iodothyronine (FT3) levels, free thyroxine (FT4) levels, antithyroid stimulating hormone receptor antibody (TRAb) levels, and thyroid volume as compared with those with thyroiditis. The mean STA-PSV of patients with Graves’ disease was significantly higher than thyroiditis and control group. Mean STA-PSV greater than 54.3 cm/s had 82.9% sensitivity and 86.2% specificity in diagnosing Graves’ disease. Mean PSV-STA/PSV-CCA ratio of 0.40 was 80.5% sensitive and 86.2% specific for Graves’ disease. Conclusion Mean STA-PSV has high sensitivity and specificity in differentiating Graves’ disease from thyroiditis and can be used routinely in clinical practice as a cheap and invaluable diagnostic tool.

Quantitative Color Doppler Ultrasonography Measurement of Thyroid Blood Flow in Patients with Graves’ Disease

2020 ◽  
Vol 16 (9) ◽  
pp. 1111-1124 ◽  
Author(s):  
Ruken Yuksekkaya ◽  
Fatih Celikyay ◽  
Serdar S. Gul ◽  
Mehmet Yuksekkaya ◽  
Faruk Kutluturk ◽  
...  
Keyword(s):  
Blood Flow ◽  
Diagnostic Performance ◽  
Doppler Ultrasonography ◽  
Color Doppler ◽  
Autoimmune Disorder ◽  
Color Doppler Ultrasonography ◽  
Graves Disease ◽  
Flow Parameters ◽  
Positive Correlations ◽  
Technetium Uptake

Background: Graves’ Disease is an autoimmune disorder characterized by increased levels of thyroid hormones correlated with increased thyroid blood flow. Thyroid scintigraphy is an important and conventional method. However, it has limited accessibility, has ionizing radiation, and is expensive. Objectives: To investigate the thyroid blood flow in patients with Graves’ Disease by color Doppler Ultrasonography and a newly developed software Color Quantification. Methods: Forty-one consecutive subjects with GD and 41 healthy controls were enrolled. Color Doppler ultrasonography parameters of the thyroid arteries and Color Quantification values of the gland were measured by a radiologist. The correlations between thyroid blood flow parameters, levels of 99mTechnetium pertechnetate uptake, thyrotropin, and free thyroxine were evaluated. The diagnostic performances of these parameters were investigated. Results: The peak systolic-end diastolic velocities of thyroid arteries and Color Quantification values were increased in the study group (p < 0.05 for all). We observed negative correlations between thyrotropin levels and peak-systolic and end-diastolic velocities of superior thyroid arteries and Color Quantification values. There were positive correlations between 99mTechnetium uptake levels and thyroid blood flow parameters (p < 0.05 for all). In the diagnostic performance of thyroid blood flow parameters, we observed utilities significantly in peak-systolic and end-diastolic velocities of thyroid arteries and Color Quantification values (p < 0.05 for all). Conclusion: The increased peak-systolic and end-diastolic velocities of thyroid arteries, and increased Color Quantification values might be helpful in the diagnosis of Graves’ Disease.

scholarly journals Evaluation of Orbital Blood Flow in Age-Related Macular Degeneration by Color Doppler Ultrasonography

2020 ◽  
Vol 27 (2) ◽  
pp. 177-183
Author(s):  
Mine Karahan ◽  
Deniz Kilic ◽  
Mehmet Emin Dursun ◽  
Birgül Dursun ◽  
Aslı Uğurlu ◽  
...  
Keyword(s):  
Blood Flow ◽  
Macular Degeneration ◽  
Doppler Ultrasonography ◽  
Color Doppler ◽  
Color Doppler Ultrasonography ◽  
Age Related Macular Degeneration ◽  
Age Related

Intratumoral blood flow in cervical cancer as assessed by transvaginal color doppler ultrasonography: Correlation with tumor characteristics

2003 ◽  
Vol 13 (4) ◽  
pp. 510-514 ◽  
Author(s):  
J. L. Alcázar ◽  
G. Castillo ◽  
M. Jurado ◽  
G. LÓPEZ-GARCÍA
Keyword(s):  
Cervical Cancer ◽  
Blood Flow ◽  
Doppler Ultrasonography ◽  
Color Doppler ◽  
Resistance Index ◽  
Color Doppler Ultrasonography ◽  
Advanced Stage ◽  
Histologic Type ◽  
Subjective Impression ◽  
Poorly Differentiated

The objective of this study was to evaluate whether intratumoral blood flow as assessed by transvaginal color Doppler ultrasonography (TVCD) correlates with some tumor features in cervical cancer. Clinical, sonographic, and histologic data on 49 women (mean age: 50.3 years, range: 25–85 years) diagnosed as having a carcinoma from the uterine cervix were reviewed. Intratumoral blood flow was assessed by TVCD in all cases. Subjective impression of the amount of flow (scanty, moderate, or abundant) as well as the lowest resistance index (RI) and highest peak systolic velocity (PSV, cm/s) were used for analysis. These data were correlated with some tumoral features such as histologic type, histologic grade, tumor volume, and tumor stage. Intratumoral blood flow was found in all cases. Abundant blood flow was found more frequently in squamous carcinoma, moderately or poorly differentiated tumors, tumors with larger volume, and advanced stage tumors (P < 0.0001). Significantly lower RI was found in moderately or poorly differentiated tumors and advanced stage tumors (P < 0.01) and significantly higher PSV was found in moderately or poorly differentiated tumors, tumors with larger volume, and advanced stage tumors (P < 0.01). No correlation was found between RI and PSV and histologic type. Our data indicate that intratumoral blood flow as assessed by TVCD correlates well with some tumor features in cervical cancer.

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