scholarly journals A Rapid Association Test Procedure Robust under Different Genetic Models Accounting for Population Stratification

2013 ◽  
Vol 75 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Wenan Chen ◽  
Xiangning Chen ◽  
Kellie J. Archer ◽  
Nianjun Liu ◽  
Qizhai Li ◽  
...  
Keyword(s):  
Population Stratification ◽  
Test Procedure ◽  
Association Test ◽  
Genetic Models

scholarly journals The genetic effect of the ICAM1 (intercellular adhesion molecule 1) rs5498 polymorphism on the susceptibility towards multiple sclerosis

2018 ◽  
Vol 38 (6) ◽  
Author(s):  
Chuan Jiang ◽  
Chunli Xie ◽  
Jianli Feng ◽  
Maolin Hao
Keyword(s):  
Multiple Sclerosis ◽  
Adhesion Molecule ◽  
Intercellular Adhesion ◽  
Association Test ◽  
Genetic Models ◽  
Sensitivity Analyses ◽  
Intercellular Adhesion Molecule ◽  
Intercellular Adhesion Molecule 1 ◽  
Case Control Studies ◽  
Published Evidence

In the present study, we included currently published evidence to comprehensively evaluate the influence of the rs5498 polymorphism within the ICAM1 (intercellular adhesion molecule 1) gene on the genetic risk of multiple sclerosis. STATA 12.0 software was utilized to carry out the heterogeneity assessment, association test, and Begg’s test as well as the Egger’s tests and sensitivity analyses. A total of 11 high-quality case–control studies were selected from the initially retrieved 2209 articles. The lack of high heterogeneity led to the use of a fixed-effect model in all genetic models. The results of the association test showed a reduced risk of multiple sclerosis in the allelic G vs A (Passociation = 0.036, OR = 0.91) and dominant AG+GG vs AA (Passociation = 0.042, OR = 0.85) but not in other genetic models (all Passociation > 0.05). In addition, the negative results were observed in further subgroup analyses based on ethnicity or Hardy-Weinberg equilibrium in all genetic models. Data from Begg’s and Egger’s tests further excluded the presence of remarkable publication bias, while sensitivity analysis data supported stable outcomes. Thus, we conclude that ICAM1 rs5498 may not be related to the risk of multiple sclerosis in Caucasian or Asian populations, which still merits further research.

CAPL: a novel association test using case-control and family data and accounting for population stratification

2010 ◽  
Vol 34 (7) ◽  
pp. 747-755 ◽  
Author(s):  
Ren-Hua Chung ◽  
Michael A. Schmidt ◽  
Richard W. Morris ◽  
Eden R. Martin
Keyword(s):  
Population Stratification ◽  
Case Control ◽  
Association Test ◽  
Family Data ◽  
Novel Association

scholarly journals The sociocultural integratedness of figurative sphere and social well-being as predictors of commitment to a country

2016 ◽  
Vol 7 (3) ◽  
pp. 76-92 ◽  
Author(s):  
S.V. Frolova
Keyword(s):  
Empirical Research ◽  
Test Procedure ◽  
Well Being ◽  
Association Test ◽  
Theoretical Studies ◽  
Topical Issue ◽  
Social Community ◽  
High Satisfaction

The article is devoted to the topical issue of social and cognitive grounds of commitment to a social community of a country and describes the results of the empirical research of the role of figurative sphere and social well-being of an individual in emergence of sovereign emigration intentions. The author has operationalized the notion of socioculturally integrated personality imaginative sphere and has designed the image and association test procedure to determine the intensity of the phenomenon, meant by the notion. 200 people (120 females and 80 males) aged 18 to 35 took part in the experiment. The research has revealed that commitment to one’s country is connected with high socioculturally integrated personality imaginative sphere. It has also proved that emigration intentions occur among both individuals with low and high satisfaction with social well-being. Low socioculturally integrated personality imaginative sphere appears to be one of the major predictors of sovereign emigration intentions. The article can be an interesting basis for further empirical and theoretical studies. This work was supported by the Russian Foundation for Humanities (project № 16-06-50134 «Commitment to one's country and emigration intentions: social and cognitive grounds»).

Men Are Hierarchical, Women Are Egalitarian: An Implicit Gender Stereotype

2004 ◽  
Vol 63 (2) ◽  
pp. 107-111 ◽  
Author(s):  
Marianne Schmid Mast
Keyword(s):  
Empirical Evidence ◽  
Implicit Association Test ◽  
Gender Stereotype ◽  
Association Test ◽  
Implicit Association ◽  
Two Samples

The goal of the present study was to provide empirical evidence for the existence of an implicit hierarchy gender stereotype indicating that men are more readily associated with hierarchies and women are more readily associated with egalitarian structures. To measure the implicit hierarchy gender stereotype, the Implicit Association Test (IAT, Greenwald et al., 1998) was used. Two samples of undergraduates (Sample 1: 41 females, 22 males; Sample 2: 35 females, 37 males) completed a newly developed paper-based hierarchy-gender IAT. Results showed that there was an implicit hierarchy gender stereotype: the association between male and hierarchical and between female and egalitarian was stronger than the association between female and hierarchical and between male and egalitarian. Additionally, men had a more pronounced implicit hierarchy gender stereotype than women.

What Does the Implicit Association Test Measure? A Test of the Convergent and Discriminant Validity of Prejudice-Related IATs

2002 ◽  
Vol 49 (3) ◽  
pp. 171-180 ◽  
Author(s):  
Bertram Gawronski
Keyword(s):  
Implicit Association Test ◽  
Discriminant Validity ◽  
Association Test ◽  
Recent Criticism ◽  
Implicit Association ◽  
East Asians ◽  
Student Sample ◽  
Convergent And Discriminant Validity ◽  
Explicit Prejudice ◽  
Turkish People

Abstract. Drawing on recent criticism of the Implicit Association Test (IAT), the present study tested the convergent and discriminant validity of two prejudice-related IATs to corresponding explicit prejudice measures in a German student sample (N = 61). Confirming convergent validity, (a) an IAT designed to assess negative associations related to Turkish people was significantly related to the explicit endorsement of prejudiced beliefs about Turkish people, and (b) an IAT designed to assess negative associations related to East Asians was significantly related to explicit prejudice against East Asians. Moreover, confirming discriminant validity, (c) the Asian IAT was unrelated to the explicit endorsement of prejudiced beliefs about Turkish people, and (d) the Turkish IAT was unrelated to explicit prejudice against Asian people. These results further corroborate the assumption that the IAT is a valid method to assess the strength of evaluative associations in the domain of prejudice and stereotypes.

Items’ Cross-Category Associations as a Confounding Factor in the Implicit Association Test

2001 ◽  
Vol 48 (2) ◽  
pp. 123-134 ◽  
Author(s):  
Melanie C. Steffens ◽  
Inga Plewe
Keyword(s):  
Implicit Association Test ◽  
Confounding Factor ◽  
Reaction Times ◽  
Association Test ◽  
The Other ◽  
Reaction Time Difference ◽  
Implicit Association ◽  
Male And Female ◽  
Research Activities ◽  
Degree Of Association

Abstract. The introduction of the Implicit Association Test (IAT; Greenwald, McGhee, & Schwartz, 1998 ) has stimulated numerous research activities. The IAT is supposed to measure the degree of association between concepts. Instances have to be assigned to these concepts by pressing appropriate keys as quickly as possible. The reaction time difference between certain conditions, termed the IAT effect, is used as an indicator of the degree of the concepts’ association. We tested the hypothesis that the degree of association between one concept (or category) and the instances of the other presented concept also influences reaction times. In our experiment, the instances in the target categories, male and female names, were kept constant. The adjectives in the evaluative categories were manipulated: Either the pleasant adjectives were female-associated and the unpleasant adjectives were male-associated, or vice versa. These stereotypic associations were indeed found to exert a substantial influence on the size of the IAT effect. This finding casts doubt on the assumption that the IAT effect may be interpreted as a pure measure of the degree of association between concepts.

Benefits from Computerized Adaptive Testing as Seen in Simulation Studies

1999 ◽  
Vol 15 (2) ◽  
pp. 91-98 ◽  
Author(s):  
Lutz F. Hornke
Keyword(s):  
Measurement Error ◽  
Computerized Adaptive Testing ◽  
Test Procedure ◽  
Adaptive Testing ◽  
Parameter Estimates ◽  
Simulation Studies ◽  
Computerized Adaptive Test ◽  
Item Banks ◽  
Item Parameters ◽  
General Reliability

Summary: Item parameters for several hundreds of items were estimated based on empirical data from several thousands of subjects. The logistic one-parameter (1PL) and two-parameter (2PL) model estimates were evaluated. However, model fit showed that only a subset of items complied sufficiently, so that the remaining ones were assembled in well-fitting item banks. In several simulation studies 5000 simulated responses were generated in accordance with a computerized adaptive test procedure along with person parameters. A general reliability of .80 or a standard error of measurement of .44 was used as a stopping rule to end CAT testing. We also recorded how often each item was used by all simulees. Person-parameter estimates based on CAT correlated higher than .90 with true values simulated. For all 1PL fitting item banks most simulees used more than 20 items but less than 30 items to reach the pre-set level of measurement error. However, testing based on item banks that complied to the 2PL revealed that, on average, only 10 items were sufficient to end testing at the same measurement error level. Both clearly demonstrate the precision and economy of computerized adaptive testing. Empirical evaluations from everyday uses will show whether these trends will hold up in practice. If so, CAT will become possible and reasonable with some 150 well-calibrated 2PL items.

Implicit Association Test: Separating Transsituationally Stable and Variable Components of Attitudes toward Gay Men

2003 ◽  
Vol 50 (1) ◽  
pp. 33-48 ◽  
Author(s):  
Melanie C. Steffens ◽  
Axel Buchner
Keyword(s):  
Gay Men ◽  
Implicit Association Test ◽  
Structural Equation ◽  
Implicit Attitudes ◽  
Association Test ◽  
Situational Factors ◽  
Situational Factor ◽  
Equation Modeling ◽  
Implicit Attitude ◽  
Implicit Association

Implicit attitudes are conceived of as formed in childhood, suggesting extreme stability. At the same time, it has been shown that implicit attitudes are influenced by situational factors, suggesting variability by the moment. In the present article, using structural equation modeling, we decomposed implicit attitudes towards gay men into a person factor and a situational factor. The Implicit Association Test ( Greenwald, McGhee, & Schwartz, 1998 ), introduced as an instrument with which individual differences in implicit attitudes can be measured, was used. Measurement was repeated after one week (Experiment 1) or immediately (Experiment 2). Explicit attitudes towards gay men as assessed by way of questionnaires were positive and stable across situations. Implicit attitudes were relatively negative instead. Internal consistency of the implicit attitude assessment was exemplary. However, the within-situation consistency was accompanied by considerable unexplained between-situation variability. Consequently, it may not be adequate to interpret an individual implicit attitude measured at a given point in time as a person-related, trait-like factor.

Does the Name-Race Implicit Association Test Measure Racial Prejudice?

2011 ◽  
Vol 58 (4) ◽  
pp. 271-277 ◽  
Author(s):  
Don van Ravenzwaaij ◽  
Han L. J. van der Maas ◽  
Eric-Jan Wagenmakers
Keyword(s):  
Diffusion Model ◽  
Implicit Association Test ◽  
Alternative Explanation ◽  
Group Membership ◽  
Racial Prejudice ◽  
Decision Time ◽  
Association Test ◽  
Implicit Association ◽  
Model Decomposition ◽  
Test Measure

Research using the Implicit Association Test (IAT) has shown that names labeled as Caucasian elicit more positive associations than names labeled as non-Caucasian. One interpretation of this result is that the IAT measures latent racial prejudice. An alternative explanation is that the result is due to differences in in-group/out-group membership. In this study, we conducted three different IATs: one with same-race Dutch names versus racially charged Moroccan names; one with same-race Dutch names versus racially neutral Finnish names; and one with Moroccan names versus Finnish names. Results showed equivalent effects for the Dutch-Moroccan and Dutch-Finnish IATs, but no effect for the Finnish-Moroccan IAT. This suggests that the name-race IAT-effect is not due to racial prejudice. A diffusion model decomposition indicated that the IAT-effects were caused by changes in speed of information accumulation, response conservativeness, and non-decision time.

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